CA2246308A1 - Method for quantifying cholesterol in high-density lipoprotein - Google Patents

Method for quantifying cholesterol in high-density lipoprotein

Info

Publication number
CA2246308A1
CA2246308A1 CA002246308A CA2246308A CA2246308A1 CA 2246308 A1 CA2246308 A1 CA 2246308A1 CA 002246308 A CA002246308 A CA 002246308A CA 2246308 A CA2246308 A CA 2246308A CA 2246308 A1 CA2246308 A1 CA 2246308A1
Authority
CA
Canada
Prior art keywords
density lipoprotein
cholesterol
high density
quantifying cholesterol
hdl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002246308A
Other languages
French (fr)
Other versions
CA2246308C (en
Inventor
Hiroshi Matsui
Yasuki Ito
Shuichi Ohara
Akira Fujiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Denka Seiken Co Ltd
Original Assignee
Denka Seiken Co., Ltd.
Hiroshi Matsui
Yasuki Ito
Shuichi Ohara
Akira Fujiwara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denka Seiken Co., Ltd., Hiroshi Matsui, Yasuki Ito, Shuichi Ohara, Akira Fujiwara filed Critical Denka Seiken Co., Ltd.
Priority to CA002637805A priority Critical patent/CA2637805A1/en
Publication of CA2246308A1 publication Critical patent/CA2246308A1/en
Application granted granted Critical
Publication of CA2246308C publication Critical patent/CA2246308C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Abstract

Disclosed is a method for quantifying cholesterol in HDL, which does not require complex fragmentation and separation operations, and by which the HDL cholesterol in test samples containing HDL and other lipoproteins such as low density lipoprotein (LDL), very low density lipoprotein (VLDL) and chylomicron (CM) may be quantified selectively, simply and accurately. The method for quantifying cholesterol in high density lipoprotein comprises a first step of erasing cholesterol in lipoproteins other than high density lipoprotein in a test sample, and a second step of adding a surfactant which specifically acts on high density lipoprotein to the product of the first step and enzymatically quantifying cholesterol in high density lipoprotein.
CA002246308A 1996-12-09 1997-12-04 Method for quantifying cholesterol in high-density lipoprotein Expired - Lifetime CA2246308C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002637805A CA2637805A1 (en) 1996-12-09 1997-12-04 Method for quantifying cholesterol in high density lipoprotein

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34464996 1996-12-09
JP8/344649 1996-12-09
PCT/JP1997/004442 WO1998026090A1 (en) 1996-12-09 1997-12-04 Method of determining cholesterol content of high-density lipoproteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002637805A Division CA2637805A1 (en) 1996-12-09 1997-12-04 Method for quantifying cholesterol in high density lipoprotein

Publications (2)

Publication Number Publication Date
CA2246308A1 true CA2246308A1 (en) 1998-06-18
CA2246308C CA2246308C (en) 2008-11-18

Family

ID=18370907

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002637805A Abandoned CA2637805A1 (en) 1996-12-09 1997-12-04 Method for quantifying cholesterol in high density lipoprotein
CA002246308A Expired - Lifetime CA2246308C (en) 1996-12-09 1997-12-04 Method for quantifying cholesterol in high-density lipoprotein

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002637805A Abandoned CA2637805A1 (en) 1996-12-09 1997-12-04 Method for quantifying cholesterol in high density lipoprotein

Country Status (8)

Country Link
US (2) US6479249B2 (en)
EP (1) EP0887422B1 (en)
JP (1) JP3164829B2 (en)
AT (1) ATE304608T1 (en)
CA (2) CA2637805A1 (en)
DE (1) DE69734194T2 (en)
ES (1) ES2248856T3 (en)
WO (1) WO1998026090A1 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE400816T1 (en) * 1999-03-01 2008-07-15 Sysmex Corp METHOD FOR TESTING BIOLOGICAL SAMPLE COMPONENTS
EP1164376B1 (en) * 1999-03-24 2006-05-24 Daiichi Pure Chemicals Co., Ltd. Method for quantitating cholesterol
DE60028776T2 (en) * 1999-06-21 2007-05-24 Daiichi Pure Chemicals Co. Ltd. PROCESS FOR PRE-TESTING SAMPLES AND QUANTIFYING CHOLESTEROL IN SPECIFIC LIPOPROTEINS
CN1187609C (en) * 1999-11-22 2005-02-02 松下电器产业株式会社 Cholesterol sensor and method for determining cholesterol
US7250269B2 (en) * 2001-01-31 2007-07-31 Asahi Kasei Pharma Corporation Composition for assaying glycoprotein
EP1477570B1 (en) * 2002-01-30 2008-01-16 DENKA SEIKEN Co., Ltd. Method of quantifying cholesterol in high density lipoprotein and reagent compositions
WO2004035816A1 (en) * 2002-10-16 2004-04-29 Kyowa Medex Co., Ltd. Method and reagent for measuring cholesterol in high density lipoproteins
MXPA05005708A (en) * 2002-11-27 2005-07-26 Daiichi Pure Chemicals Co Ltd Method of measuring lipid in specific lipoprotein.
CN101373190A (en) * 2002-11-27 2009-02-25 积水医疗株式会社 Method of measuring lipid in specific lipoprotein
AU2003289081B2 (en) 2002-12-13 2009-11-19 Denka Company Limited Method of multiple quantification of cholesterol in low-density lipoproteins
US20050037504A1 (en) * 2003-07-17 2005-02-17 Dimagno Theodore John One-step assay for high-density lipoprotein cholesterol
US20050032141A1 (en) * 2003-07-17 2005-02-10 Dimagno Theodore John Dry analytical element for high-density lipoprotein cholesterol quantification
US7435577B2 (en) * 2004-02-03 2008-10-14 Polymer Technology Systems, Inc. Direct measurement of chlolesterol from low density lipoprotein with test strip
CN100564539C (en) * 2004-12-31 2009-12-02 浙江伊利康生物技术有限公司 The mensuration reagent and the preparation method of cholesterol in the high-density lipoprotein (HDL)
WO2007007392A1 (en) 2005-07-11 2007-01-18 Wako Pure Chemical Industries, Ltd. Novel polymer and method of measuring cholesterol therewith
JP5129572B2 (en) * 2005-09-30 2013-01-30 デンカ生研株式会社 Method for simultaneous fractionation and quantification of two measurement objects in biological samples
JP5534644B2 (en) * 2005-12-09 2014-07-02 協和メデックス株式会社 Method, reagent and kit for measuring cholesterol in remnant-like lipoprotein
GB0609494D0 (en) * 2006-05-12 2006-06-21 Oxford Biosensors Ltd HDL cholesterol sensor using specific surfactant
GB0609493D0 (en) * 2006-05-12 2006-06-21 Oxford Biosensors Ltd Cholesterol sensor
WO2008087895A1 (en) * 2007-01-15 2008-07-24 Toyo Boseki Kabushiki Kaisha Method for determination of high-density lipoprotein cholesterol, and reagent for the method
JP5448317B2 (en) 2007-09-12 2014-03-19 デンカ生研株式会社 Method for reducing measurement error due to catalase inhibition by azide
JP4640400B2 (en) * 2007-09-28 2011-03-02 和光純薬工業株式会社 Component measurement reagent using catalase stabilizer
EP2065708B1 (en) 2007-11-28 2014-01-01 FUJIFILM Corporation Method for measuring high-density lipoprotein cholesterol
JP5313537B2 (en) 2008-04-10 2013-10-09 富士フイルム株式会社 Dry analytical element for high density lipoprotein cholesterol measurement
JP5813284B2 (en) 2009-10-26 2015-11-17 デンカ生研株式会社 Method for measuring cholesterol in ApoE-containing HDL
JP5766426B2 (en) 2010-11-10 2015-08-19 デンカ生研株式会社 Method for quantifying remnant-like lipoprotein cholesterol and kit therefor
JP5925026B2 (en) * 2011-04-28 2016-05-25 アークレイ株式会社 Dry specimen for creatinine measurement and creatinine measurement method
US9695464B2 (en) 2011-11-11 2017-07-04 Axis-Shield As Blood sample assay method
JP2013103086A (en) 2011-11-16 2013-05-30 Mtg:Kk Beauty instrument
JP6054051B2 (en) 2012-04-11 2016-12-27 デンカ生研株式会社 Method for determining subfraction of cholesterol (-C) in high density lipoprotein (HDL)
ES2831380T3 (en) 2013-03-15 2021-06-08 Helena Laboratories Corp System and method for evaluating amounts or sizes of lipoprotein particles of compositions of lipoprotein particles
JP6182008B2 (en) * 2013-07-24 2017-08-16 デンカ生研株式会社 Method and reagent for quantifying cholesterol in high density lipoprotein 3
CN105492623B (en) 2013-08-30 2019-01-15 积水医疗株式会社 Reagent used in method for determination of cholesterol and this method in high-density lipoprotein
JP6829009B2 (en) 2016-05-24 2021-02-10 デンカ株式会社 Triglyceride-rich lipoprotein quantification method and quantification reagent
JP2017060522A (en) * 2016-12-20 2017-03-30 デンカ生研株式会社 Quantitative method of cholesterol in high density lipoprotein (hdl)
US11407827B2 (en) * 2018-03-14 2022-08-09 Technion Research & Development Foundation Limited Prognostic biomarker in cancer
WO2019177093A1 (en) * 2018-03-15 2019-09-19 デンカ生研株式会社 Method for quantifying cholesterol in high-density lipoprotein
JP7134667B2 (en) 2018-03-28 2022-09-12 デンカ株式会社 Method for quantifying lipoprotein cholesterol, quantitative reagent, and quantitative kit
JP7029139B2 (en) 2018-08-23 2022-03-03 デンカ株式会社 How to help detect non-alcoholic steatohepatitis
CN115004033A (en) 2020-02-04 2022-09-02 电化株式会社 Method for auxiliary detection of nonalcoholic steatohepatitis
JP7437239B2 (en) 2020-06-02 2024-02-22 デンカ株式会社 Lipoprotein cholesterol quantification methods and kits
JP7455674B2 (en) 2020-06-02 2024-03-26 デンカ株式会社 Kits and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208253A1 (en) 1982-03-08 1983-09-15 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR SPECIFIC DETERMINATION OF THE CHOLESTERIN OF THE LDL FRACTION IN SERUM
DE3533288A1 (en) * 1985-09-18 1987-03-26 Boehringer Mannheim Gmbh METHOD AND REAGENT FOR SPECIFIC DETERMINATION OF HDL CHOLESTEROL IN SERUM
DE3636851A1 (en) * 1986-10-29 1988-05-11 Boehringer Mannheim Gmbh METHOD AND REAGENT FOR SPECIFIC DETERMINATION OF THE CHOLESTERIN OF THE HDL FACTION
US5215886A (en) * 1987-06-22 1993-06-01 Patel P Jivan HDL determination in whole blood
WO1992021015A1 (en) 1991-05-23 1992-11-26 Seman Leo J Jr METHOD FOR DETECTING LIPOPROTEIN (a) AND ASSOCIATED CHOLESTEROL
JP2653755B2 (en) 1994-03-08 1997-09-17 協和メデックス株式会社 Determination of cholesterol in high density lipoprotein
JP3107492B2 (en) 1994-04-05 2000-11-06 国際試薬株式会社 Method for quantification of components in lipoprotein fraction
JPH08116996A (en) * 1994-10-26 1996-05-14 Toyobo Co Ltd Measurement of hdl-cholesterol in serum or plasma
JP2799835B2 (en) 1995-01-31 1998-09-21 第一化学薬品株式会社 How to determine cholesterol
JP3614514B2 (en) * 1995-06-21 2005-01-26 国際試薬株式会社 Method for quantifying cholesterol in high-density lipoprotein fraction and reagent kit for quantification

Also Published As

Publication number Publication date
ATE304608T1 (en) 2005-09-15
CA2246308C (en) 2008-11-18
DE69734194T2 (en) 2006-06-29
WO1998026090A1 (en) 1998-06-18
ES2248856T3 (en) 2006-03-16
US20020001819A1 (en) 2002-01-03
JP3164829B2 (en) 2001-05-14
DE69734194D1 (en) 2005-10-20
CA2637805A1 (en) 1998-06-18
EP0887422A1 (en) 1998-12-30
EP0887422A4 (en) 2002-10-23
US6479249B2 (en) 2002-11-12
EP0887422B1 (en) 2005-09-14
US20020192732A1 (en) 2002-12-19
US6893832B2 (en) 2005-05-17

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Effective date: 20171204