DE68919772T2 - Liposomen, an deren Oberfläche die Adsorption on Proteinen verhindert wird. - Google Patents

Liposomen, an deren Oberfläche die Adsorption on Proteinen verhindert wird.

Info

Publication number
DE68919772T2
DE68919772T2 DE68919772T DE68919772T DE68919772T2 DE 68919772 T2 DE68919772 T2 DE 68919772T2 DE 68919772 T DE68919772 T DE 68919772T DE 68919772 T DE68919772 T DE 68919772T DE 68919772 T2 DE68919772 T2 DE 68919772T2
Authority
DE
Germany
Prior art keywords
liposomes
adsorption
proteins
prevented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68919772T
Other languages
English (en)
Other versions
DE68919772D1 (de
Inventor
Hiroshi Yoshida
Hiroshi Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of DE68919772D1 publication Critical patent/DE68919772D1/de
Publication of DE68919772T2 publication Critical patent/DE68919772T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
DE68919772T 1988-08-11 1989-08-11 Liposomen, an deren Oberfläche die Adsorption on Proteinen verhindert wird. Expired - Lifetime DE68919772T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19891588 1988-08-11
JP1063507A JPH0720857B2 (ja) 1988-08-11 1989-03-17 リポソームおよびその製法

Publications (2)

Publication Number Publication Date
DE68919772D1 DE68919772D1 (de) 1995-01-19
DE68919772T2 true DE68919772T2 (de) 1995-07-13

Family

ID=26404636

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68919772T Expired - Lifetime DE68919772T2 (de) 1988-08-11 1989-08-11 Liposomen, an deren Oberfläche die Adsorption on Proteinen verhindert wird.

Country Status (5)

Country Link
US (3) US5676971A (de)
EP (1) EP0354855B1 (de)
JP (1) JPH0720857B2 (de)
DE (1) DE68919772T2 (de)
ES (1) ES2064470T3 (de)

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US5462990A (en) * 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5380536A (en) 1990-10-15 1995-01-10 The Board Of Regents, The University Of Texas System Biocompatible microcapsules
JP3220180B2 (ja) * 1991-05-23 2001-10-22 三菱化学株式会社 薬剤含有タンパク質結合リポソーム
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JPWO2011083845A1 (ja) * 2010-01-08 2013-05-16 富士フイルム株式会社 腫瘍部位に対する標的化剤
CN103037840A (zh) 2010-04-21 2013-04-10 国立大学法人北海道大学 具有核内转运性的脂质膜结构体
CN103327983A (zh) 2010-12-06 2013-09-25 梅里麦克制药股份有限公司 在使用包含蒽环类化疗剂的erbb2靶向免疫脂质体的治疗中防止心肌毒性的剂量和给药
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US9717724B2 (en) 2012-06-13 2017-08-01 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies
JP2015524410A (ja) 2012-07-18 2015-08-24 オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． エポキシケトン系プロテアソーム阻害剤のリポソーム組成物
SG11201504293WA (en) 2012-12-03 2015-06-29 Merrimack Pharmaceuticals Inc Combination therapy for treating her2-positive cancers
CA2974196C (en) 2015-01-20 2023-12-12 TetraDerm Group LLC Versatile topical drug delivery vehicle and multifactorial tissue moisturizer that provides mucosal and skin barrier restoration
US11318131B2 (en) 2015-05-18 2022-05-03 Ipsen Biopharm Ltd. Nanoliposomal irinotecan for use in treating small cell lung cancer
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ES2826826T3 (es) 2015-08-21 2021-05-19 Ipsen Biopharm Ltd Combinación farmacéutica que comprende irinotecán liposómico, oxaliplatino, 5-fluorouracilo y leucovorina para el tratamiento del cáncer pancreático metastático
SG10201912568PA (en) 2015-10-16 2020-02-27 Ipsen Biopharm Ltd Stabilizing camptothecin pharmaceutical compositions
TWI754659B (zh) 2016-08-08 2022-02-11 台灣微脂體股份有限公司 用於製備含有弱酸性劑之微脂體組合物的傳輸載體、方法及套組
MX2019004783A (es) 2016-11-02 2019-08-12 Ipsen Biopharm Ltd Tratamiento de cancer gastrico usando terapias de combinacion que comprenden irinotecan liposomico oxaliplatino, 5-fluoruracilo (y leucovorina).
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Also Published As

Publication number Publication date
EP0354855A2 (de) 1990-02-14
ES2064470T3 (es) 1995-02-01
JPH02149512A (ja) 1990-06-08
EP0354855A3 (de) 1991-06-05
JPH0720857B2 (ja) 1995-03-08
US5676971A (en) 1997-10-14
US5593622A (en) 1997-01-14
DE68919772D1 (de) 1995-01-19
EP0354855B1 (de) 1994-12-07
US5846458A (en) 1998-12-08

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