EP1141419A4 - Methods and compositions for identifying protease modulators - Google Patents
Methods and compositions for identifying protease modulatorsInfo
- Publication number
- EP1141419A4 EP1141419A4 EP99966678A EP99966678A EP1141419A4 EP 1141419 A4 EP1141419 A4 EP 1141419A4 EP 99966678 A EP99966678 A EP 99966678A EP 99966678 A EP99966678 A EP 99966678A EP 1141419 A4 EP1141419 A4 EP 1141419A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- identifying protease
- protease modulators
- modulators
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11358998P | 1998-12-24 | 1998-12-24 | |
US113589P | 1998-12-24 | ||
PCT/US1999/031026 WO2000039348A1 (en) | 1998-12-24 | 1999-12-23 | Methods and compositions for identifying protease modulators |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1141419A1 EP1141419A1 (en) | 2001-10-10 |
EP1141419A4 true EP1141419A4 (en) | 2002-03-20 |
Family
ID=22350343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99966678A Withdrawn EP1141419A4 (en) | 1998-12-24 | 1999-12-23 | Methods and compositions for identifying protease modulators |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1141419A4 (en) |
AU (1) | AU2217800A (en) |
WO (1) | WO2000039348A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002038799A2 (en) * | 2000-11-07 | 2002-05-16 | University Of Victoria Innovation And Development Corporation | Detection of proteases and screening for protease inhibitors |
WO2003035832A2 (en) * | 2001-10-22 | 2003-05-01 | Exelixis, Inc. | Ctsls as modifiers of the p53 and apaf-1 pathways and methods of use |
CA2474130C (en) * | 2002-01-29 | 2011-04-05 | Pyare Khanna | Enzyme activation protease assay |
US7452690B2 (en) | 2003-01-28 | 2008-11-18 | Discoverx Corporation | Protease EFC cell surface fusion protein assay |
EP1994178A4 (en) | 2006-03-13 | 2009-11-11 | Univ Leland Stanford Junior | Detection of molecular interactions using a reduced affinity enzyme complementation reporter system |
US8101373B2 (en) | 2007-10-12 | 2012-01-24 | Discoverx Corporation | β-galactosidase donor fragments |
WO2012178079A1 (en) | 2011-06-23 | 2012-12-27 | Discoverx Corporation | Monitoring protein trafficking using beta-galactosidase reporter fragment complementation |
US20200308591A1 (en) * | 2019-03-28 | 2020-10-01 | Eurofins Discoverx Corporation | Promoter region analysis methods and cells for practicing same |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015575A1 (en) * | 1990-04-04 | 1991-10-17 | Chiron Corporation | Hepatitis c virus protease |
WO1992003559A2 (en) * | 1990-08-28 | 1992-03-05 | Boehringer Ingelheim International Gmbh | Test system for checking the activity of viral proteinases |
WO1993001291A1 (en) * | 1991-07-05 | 1993-01-21 | The Johns Hopkins University | Herpes virus proteinase and method of assaying |
WO1997027320A1 (en) * | 1996-01-26 | 1997-07-31 | Boehringer Mannheim Corporation | ASSAYS USING CROSS-LINKED POLYPEPTIDE FRAGMENTS OF β-GALACTOSIDASE |
WO1999006537A1 (en) * | 1997-07-30 | 1999-02-11 | Boehringer Mannheim Corporation | Cross-linked polypeptide assay components |
-
1999
- 1999-12-23 AU AU22178/00A patent/AU2217800A/en not_active Abandoned
- 1999-12-23 EP EP99966678A patent/EP1141419A4/en not_active Withdrawn
- 1999-12-23 WO PCT/US1999/031026 patent/WO2000039348A1/en not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015575A1 (en) * | 1990-04-04 | 1991-10-17 | Chiron Corporation | Hepatitis c virus protease |
WO1992003559A2 (en) * | 1990-08-28 | 1992-03-05 | Boehringer Ingelheim International Gmbh | Test system for checking the activity of viral proteinases |
WO1993001291A1 (en) * | 1991-07-05 | 1993-01-21 | The Johns Hopkins University | Herpes virus proteinase and method of assaying |
WO1997027320A1 (en) * | 1996-01-26 | 1997-07-31 | Boehringer Mannheim Corporation | ASSAYS USING CROSS-LINKED POLYPEPTIDE FRAGMENTS OF β-GALACTOSIDASE |
WO1999006537A1 (en) * | 1997-07-30 | 1999-02-11 | Boehringer Mannheim Corporation | Cross-linked polypeptide assay components |
Non-Patent Citations (1)
Title |
---|
See also references of WO0039348A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1141419A1 (en) | 2001-10-10 |
WO2000039348A1 (en) | 2000-07-06 |
AU2217800A (en) | 2000-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20010528 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: WANG, SHAOJIE Inventor name: MENZEL, ROLF |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020204 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Effective date: 20030410 |