EP1856072A4 - Thiazole derivatives as ppar delta ligands and their manufacturing process - Google Patents

Thiazole derivatives as ppar delta ligands and their manufacturing process

Info

Publication number
EP1856072A4
EP1856072A4 EP06716113A EP06716113A EP1856072A4 EP 1856072 A4 EP1856072 A4 EP 1856072A4 EP 06716113 A EP06716113 A EP 06716113A EP 06716113 A EP06716113 A EP 06716113A EP 1856072 A4 EP1856072 A4 EP 1856072A4
Authority
EP
European Patent Office
Prior art keywords
manufacturing process
thiazole derivatives
ppar delta
delta ligands
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06716113A
Other languages
German (de)
French (fr)
Other versions
EP1856072A1 (en
Inventor
Jungyeob Ham
Hoosang Hwang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seoul National University Industry Foundation
Original Assignee
Seoul National University Industry Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seoul National University Industry Foundation filed Critical Seoul National University Industry Foundation
Priority claimed from KR1020060018360A external-priority patent/KR100797798B1/en
Publication of EP1856072A1 publication Critical patent/EP1856072A1/en
Publication of EP1856072A4 publication Critical patent/EP1856072A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26Radicals substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
EP06716113A 2005-02-25 2006-02-24 Thiazole derivatives as ppar delta ligands and their manufacturing process Withdrawn EP1856072A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20050015663 2005-02-25
KR1020060018360A KR100797798B1 (en) 2005-02-25 2006-02-24 Thiazole derivatives as ppar? ligands and their manufacturing process
PCT/KR2006/000663 WO2006091047A1 (en) 2005-02-25 2006-02-24 Thiazole derivatives as ppar delta ligands and their manufacturing process

Publications (2)

Publication Number Publication Date
EP1856072A1 EP1856072A1 (en) 2007-11-21
EP1856072A4 true EP1856072A4 (en) 2009-10-21

Family

ID=36927652

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06716113A Withdrawn EP1856072A4 (en) 2005-02-25 2006-02-24 Thiazole derivatives as ppar delta ligands and their manufacturing process

Country Status (3)

Country Link
EP (1) EP1856072A4 (en)
CA (1) CA2599281C (en)
WO (1) WO2006091047A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8519145B2 (en) 2006-12-02 2013-08-27 Seoul National University Industry Foundation Aryl compounds as PPAR ligands and their use
WO2008084962A1 (en) * 2007-01-08 2008-07-17 Seoul National University Industry Foundation THIAZOLE COMPOUND (AS PPARδ) LIGAND AND PHARMACEUTICAL, COSMETIC AND HEALTH FOOD COMPRISED THEREOF
EP2540711A4 (en) * 2010-02-25 2014-01-22 Snu R&Db Foundation Selenalzole derivative having ligand which activates peroxisome proliferator activated receptor (ppar), preparing method thereof and usage of the chemical compounds
AU2011296737A1 (en) 2010-08-31 2013-04-11 Snu R&Db Foundation Use of the fetal reprogramming of a PPAR delta agonist

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062774A1 (en) * 2000-12-20 2002-08-15 Glaxo Group Limited Thiazole derivatives for treating ppar related disorders
WO2003072100A1 (en) * 2002-02-25 2003-09-04 Eli Lilly And Company Peroxisome proliferator activated receptor modulators
WO2003106442A1 (en) * 2002-05-04 2003-12-24 Heonjoong Kang Process for preparing thiazole derivative and the intermediate compounds for preparing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL345247A1 (en) * 1998-07-01 2001-12-03 Takeda Chemical Industries Ltd Retinoid-associated receptor regulators
CN1348439A (en) * 1999-04-20 2002-05-08 诺沃挪第克公司 New compounds, their preparation and use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062774A1 (en) * 2000-12-20 2002-08-15 Glaxo Group Limited Thiazole derivatives for treating ppar related disorders
WO2003072100A1 (en) * 2002-02-25 2003-09-04 Eli Lilly And Company Peroxisome proliferator activated receptor modulators
WO2003106442A1 (en) * 2002-05-04 2003-12-24 Heonjoong Kang Process for preparing thiazole derivative and the intermediate compounds for preparing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006091047A1 *

Also Published As

Publication number Publication date
EP1856072A1 (en) 2007-11-21
CA2599281A1 (en) 2006-08-31
CA2599281C (en) 2012-01-17
WO2006091047A1 (en) 2006-08-31

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070921

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION

A4 Supplementary search report drawn up and despatched

Effective date: 20090921

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 3/10 20060101ALI20090915BHEP

Ipc: A61P 3/06 20060101ALI20090915BHEP

Ipc: A61K 31/426 20060101ALI20090915BHEP

Ipc: C07D 277/26 20060101AFI20060904BHEP

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Effective date: 20140410

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Inventor name: HWANG, HOOSANG

Inventor name: HAM, JUNGYEOB

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20140821