US3746004A - Disposable electrodes for electrical stimulation of muscles and nerves of the head - Google Patents

Disposable electrodes for electrical stimulation of muscles and nerves of the head Download PDF

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US3746004A
US3746004A US00152620A US3746004DA US3746004A US 3746004 A US3746004 A US 3746004A US 00152620 A US00152620 A US 00152620A US 3746004D A US3746004D A US 3746004DA US 3746004 A US3746004 A US 3746004A
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sheet
skin
electrode
patient
planar
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B Jankelson
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes

Definitions

  • ABSTRACT Disposable electrodes capable of conforming to irregular skin surfaces comprise a flexible, electrically nonconductive planar sheet material having one surface thereof coated with a skin adhesive adapted to be applied directly to the skin of the patient, the nonconductive planar body having a projecting tab to which an electrical connection can be made.
  • a conductive foil sheet is adhered to the adhesive coating of the planar sheet, the foil being contiguous with the tab.
  • a nonconductive planar spacing sheet having a surface area smaller than that of the planar sheet is adhered to the adhesive coated surface of the sheet material to overlap a portion of the foil sheet extending from the tab and leavean exposed area of adhesive around the circumference of the spacing sheet for adhering the electrode to the skin of the patient.
  • the overlapped portion of the spacing sheet and foil creates an opening into the interior of the electrode for injection of a liquid electrolyte after the electrode is applied to the skin.
  • the spacing sheet is preferably a non-conductive fine mesh screen.
  • the electrodes are primarily USBfUll in electrically stimulating the muscle complex that works synergistically to close the human mandible.
  • FIG: 6 wg fig,@owyi fl ATTORNEYS DISPOSABLE ELECTRODES FOR ELECTRICAL STIMULATION OF MUSCLES AND NERVES OF THE HEAD BACKGROUND OF THE INVENTION 1.
  • This invention relates to disposable electrodes for electrical stimulation of muscles and nerves and to a disposable electrode assembly for electrically stimulating the facial and mandibular nerves which work synergistically to close the human mandible.
  • the device As the device is used clinically it is desirable to have a way of quickly and accurately placing electrodes in the correct positions on the patients face without causing the patient discomfort or inconvenience and yet have the electrodes conform to the skin of the individual and maintain continuous electrical contact.
  • the multiplicity of muscles enervated by the fifth and seventh cranial nerves it is necessary that the input electrodes be carefully located directly over the mandibular notch on each side of the face and contiguous to the lower lobe of the ear.
  • the fifth and seventh cranial nerves are stimulated by electrical current flowing through the input electrodes and out to a common dispersal electrode placed, preferably, over the cervical spine.
  • the foil sheet also covers a portion of the nonconductive planar sheet material.
  • a spacing sheet preferably an electrically non-conductive fine mesh screen, having a surface area smaller than the surface area of the non-conductive sheet material is adhered to the adhesive coating of the sheet material to overlap the portion of the foil extending from the tab and leave an exposed area of adhesive around the circumference of the spacing sheet for adhering the electrodes to the skin of the patient.
  • the overlapped portion of the spacing sheet and foil creates an opening into the interior of the electrode after it is placed on the skin for injection of a liquid electrolyte.
  • the electrode assembly for electrical stimulation of the. muscle complex includes two input electrodes placed on each side of the face and a dispersal electrode.
  • the planar sheet material of the two input electrodes each has a notch adjacent the projecting tab adapted to fit under the respective earlobes of the patient.
  • the notch is located so that the electrode is correctly placed for electrical stimulation of the fifth and seventh cranial nerves.
  • Conductive means leading from a pulse generating apparatus are electrically connected to each of the electrodes by means of clips attached to the respective tabs.
  • FIG. 1 is a perspective view illustrating the position of the input electrodes on the sides of the face of a patient and a dispersal electrode on the cervical spine of the patient, each of the electrodes being connected through electrical conductive means to a pulse generating apparatus;
  • FIG. 2 is a front elevation of the adhesive coated surface of one of the input electrodes of this invention.
  • FIG. 3 is a cross-sectional view of the disposable electrode of FIG. 2 prior to its separation from a backing sheet;
  • FIG. 4 is a cross-sectional view of the disposable electrode of FIG. 2 adhered to the skin of the patient;
  • FIG. 5 is a cross-sectional view of the disposable electrode of FIG. 2 illustrating the electrode adhered to the skin of the patient and an electrolyte being injected into the interior pocket formed by the spacing sheet;
  • FIG. 6 is a cross-sectional view of the disposable electrode of FIG. 2 showing electrically conductive means secured to the tab extending from the upper end of the electrode.
  • the disposable electrode assembly of this invention is primarily useful in electrical stimulation of the mus cle complex through the fifth and seventh cranial nerves with resultant involuntary closure of the human mandible.
  • the method of producing a muscularly balanced closure of the human mandible through electrical stimulation of the masticatory and facial muscles is described in detail in copending application Ser. No. 855,480, filed Sept. 5, 1970, now US. Pat. No. 3,593,422, and entitled Method of Producing a Muscularly Balanced Closure of the Human Mandible.
  • the copending application describes a method of involuntarily closing the human mandible for various clinical objectives by electrically stimulating the muscles enervated by the fifth and seventh cranial nerves on both sides of the face. Stimulation results in coordinated contraction of the masticatory and facial muscles controlling opening and closing of the mandible.
  • FIG. ll of the drawings shows a disposable input electrode and common dispersal electrode 20, secured in specified locations to the head of a patient.
  • the input electrodes are adhesively secured to the skin of the patient, one on each side of the face in a position for electrical stimulation of the fifth and seventh nerves through the mandibular notch. This is done most effectively if the electrodes are located over the opening in the bones of the face called the mandibular notch.
  • the input electrodes are formed with a shoulder portion or notch which is positioned directly under the respective earlobe of the patient. The notch locates the correct position of the electrode on the side of the patients face.
  • Each of the input electrodes comprises a flexible, planar sheet material of vinyl plastic or other suitable nonconductive material 12 having a tab portion 14 extending outwardly from the circumference of the sheet.
  • the input and dispersal electrodes are illustrated as being generally rectangular or square, the particular shape is not of any significance.
  • the input electrodes are formed with a notch or shoulder portion 16 to correctly locate the position of the input electrodes on each side of the patients face.
  • the notch should be located under the lobe of the ear such that the central portion of the electrode is directly over the mandibular notch of the patient on each side of the face for electrical stimulation of the fifth and seventh cranial nerves.
  • One side of each of the electrodes is coated with a commercially available and conventional skin adhesive. The entire surface is coated with the adhesive.
  • a strip of electrically conductive foil 18 is adhered to the adhesive-coated tabular surface 14 of the nonconductive sheet material and extends past the tab toward the central portion of the sheet material.
  • a planar, flexible, spacing sheet 19 is adhered to the adhesive-coated surface of the electrode so that it overlaps the foil extending from the tab 14.
  • the surface area of the spacing sheet 19 is smaller than that of sheet material 12 to leave an exposed area of adhesive around the outer circumference of the sheet 19 for adhering the electrode to the skin of the patient.
  • the spacing sheet should be porous for absorption of a liquid electrolyte.
  • a material which has been found to work satisfactorily and which is economical is a fine mesh screen of glass fiber which is both electrically nonconductive and capable of holding the electrolyte satisfactorily.
  • a set of electrodes which includes two input electrodes 10 and a dispersal elec trode 20 is adhered to a backing sheet 30 of conventional character.
  • the facial skin is scrubbed with alcohol or other material around the earlobes and the nape of the neck to remove skin oils and makeup.
  • the electrodes are peeled from the backing sheet 30 by holding the tab portion 14 and peeling it away from the backing sheet.
  • the input electrodes which are marked right and left are applied on each side of the face of the patient with the notch portion 16 directly under the earlobe.
  • the adhesive coated sheet 12 is pressed firmly against the skin to adhere it.
  • the dispersal electrode is applied similarly and is preferably centered at the nape of the neck directly under the hairline.
  • each of the input electrodes is then bent back to reveal an opening or pocket in the interior of the electrode where the spacing sheet is located.
  • An electrolyte preferably in gel form, is injected, as illustrated in FIG. 5, into the pocket.
  • the electrolyte is held by the porous spacing sheet.
  • the opening is partially filled and, after filling, is gently pressed to spread the gel so that good electrical contact between the skin and the metallic tab extending from the tab portion is insured.
  • Clips connected to electrically conductive wires are attached to the tab portion of each of the electrodes and to the pulse generating apparatus. When the clips are at tached, the apparatus is ready for use. After use the electrodes are removed by detaching the clips, stripping them from the skin and disposing of them.
  • the electrodes described are economically manufactured, easy to use, and have many advantages over those in common use. Although described with particular reference to electrical stimulation of the facial and mandibular muscles, the electrodes may be used in any application where electrical stimulation through the skin is necessary or where electrical pickup through the skin of the patient is needed.
  • Disposable electrodes for application directly to the skin of a patient comprising:
  • a flexible, electrically non-conductive, planar, synthetic plastic sheet having a thickness ranging from 1 to 3 mils. coated with a skin adhesive on one side thereof, the plastic sheet having a projecting tab extending from one edge of the sheet for connection to a flexible lead wire and a shoulder portion extending outwardly from an adjacent edge of the planar sheet for fitting under the earlobe of the patient to correctly place the electrode on the face of the patient for electrical stimulation of the fifth and seventh cranial nerves through the mandibular notch region, r I
  • a flexible, fine mesh, electrically non-conductive screen material adhered to the adhesive-coated surface thereof having a surface area smaller than the surface area of the non-conductive planar sheet and overlapping the portion of the foil sheet extending across the central area of the planar sheet from the tab and leaving an exposed area of adhehesive coated surface around the remaining edges sive-coated surface around the remaining edges thereof for adhering the adhesive-coated planar thereof for adhering the adhesive-coated sheet to sheet to the skin of the patient, the overlapped porthe Skin of the patient, the overlapped por ion of tion of the screen material and foil creating a the Screen material and foil creating a Pocket when 5 pocket when the electrode is adhered to the skin of the electrode assembly is adhered to the skin of the h patient f i j i of a l l t l P h for injection of a gel electrolyte" a common dispersal electrode comprising: (1 a flexi- A p electrode assembly for electrical ble, electrically nonconductive,
  • a Pulse generating apparatus fomprisihgi adapted to be secured to the skin of the patient, the a pair of mput electrodes, each of the input elecsheet having a projecting tab extending from one trodes comprising: (1) a flexible, electrically nonconductive, planar, synthetic plastic sheet having a thickness ranging from 1 to 3 mils.

Abstract

Disposable electrodes capable of conforming to irregular skin surfaces comprise a flexible, electrically nonconductive planar sheet material having one surface thereof coated with a skin adhesive adapted to be applied directly to the skin of the patient, the nonconductive planar body having a projecting tab to which an electrical connection can be made. A conductive foil sheet is adhered to the adhesive coating of the planar sheet, the foil being contiguous with the tab. A nonconductive planar spacing sheet having a surface area smaller than that of the planar sheet is adhered to the adhesive coated surface of the sheet material to overlap a portion of the foil sheet extending from the tab and leave an exposed area of adhesive around the circumference of the spacing sheet for adhering the electrode to the skin of the patient. The overlapped portion of the spacing sheet and foil creates an opening into the interior of the electrode for injection of a liquid electrolyte after the electrode is applied to the skin. The spacing sheet is preferably a non-conductive fine mesh screen. The electrodes are primarily useful in electrically stimulating the muscle complex that works synergistically to close the human mandible.

Description

United States Patent [191 Jankelson 1 1 July 17, 1973 l [22] Filed:
l l DISPOSABLE ELECTRODES FOR ELECTRICAL STIMULATION 0F MUSCLES AND NERVES OF THE HEAD [76] Inventor: Bernard Jankelson, 1451 Medical Dental Building, Seattle, Wash. 98101 June 14, I971 [211 App]. No.: 152,620
Primary Examiner-William E. Kamm Attorney-Richard W. Seed, Kenneth W. Vernon etal.
I57] ABSTRACT Disposable electrodes capable of conforming to irregular skin surfaces comprise a flexible, electrically nonconductive planar sheet material having one surface thereof coated with a skin adhesive adapted to be applied directly to the skin of the patient, the nonconductive planar body having a projecting tab to which an electrical connection can be made. A conductive foil sheet is adhered to the adhesive coating of the planar sheet, the foil being contiguous with the tab. A nonconductive planar spacing sheet having a surface area smaller than that of the planar sheet is adhered to the adhesive coated surface of the sheet material to overlap a portion of the foil sheet extending from the tab and leavean exposed area of adhesive around the circumference of the spacing sheet for adhering the electrode to the skin of the patient. The overlapped portion of the spacing sheet and foil creates an opening into the interior of the electrode for injection of a liquid electrolyte after the electrode is applied to the skin. The spacing sheet is preferably a non-conductive fine mesh screen. The electrodes are primarily USBfUll in electrically stimulating the muscle complex that works synergistically to close the human mandible.
2 Claims, 6 Drawing Figures mmmm 1m BERNARD JANKELSON INVENTOR. FIG: 6 wg fig,@owyi fl ATTORNEYS DISPOSABLE ELECTRODES FOR ELECTRICAL STIMULATION OF MUSCLES AND NERVES OF THE HEAD BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to disposable electrodes for electrical stimulation of muscles and nerves and to a disposable electrode assembly for electrically stimulating the facial and mandibular nerves which work synergistically to close the human mandible.
2. Prior Art Relating to the Disclosure Various means of making electrical contact by means of electrodes placed in contact with the skin of an indi vidual are known. Most frequently electrodes are taped to desired areas of the skin so they will remain in continuous contact. Taping of multiple electrodes has not been entirely satisfactory in many instances because of the lack of continuous electrical contact of the electrically conductive material of the electrode with the skin of the patient. The present invention is primarily useful in conjunction with a method for electrically stimulating the muscle complex that works synergisticaly to close the human mandible. Such a method is useful to dentists in fitting dentures, in correcting occlusal difficulties of patients, in reduction of swelling or discoloration after surgical operations or accidental injury, and in treatment of various nerve and/or muscle disorders associated with the facial muscles. As the device is used clinically it is desirable to have a way of quickly and accurately placing electrodes in the correct positions on the patients face without causing the patient discomfort or inconvenience and yet have the electrodes conform to the skin of the individual and maintain continuous electrical contact. For simultaneous and even stimulation the multiplicity of muscles enervated by the fifth and seventh cranial nerves, it is necessary that the input electrodes be carefully located directly over the mandibular notch on each side of the face and contiguous to the lower lobe of the ear. When so located the fifth and seventh cranial nerves are stimulated by electrical current flowing through the input electrodes and out to a common dispersal electrode placed, preferably, over the cervical spine. There is considerable variation of compressibility of the skin tissues in the area around the mandibular notch. In some areas, such as the zygomatic arch, bone closely underlies the skin and soft tissue while in other areas, such as the mandibular notch, there is an absence of bony support. In general the thickness and compressibility of tissues of the input area vary considerably, and for that reason, flat metal electrodes do not conform to the variations in contour.
Therefore, electrical contact is hard to maintain with metal electrodes adhered to the skin.
SUMMARY OF THE INVENTION sheet. The foil sheet also covers a portion of the nonconductive planar sheet material. A spacing sheet, preferably an electrically non-conductive fine mesh screen, having a surface area smaller than the surface area of the non-conductive sheet material is adhered to the adhesive coating of the sheet material to overlap the portion of the foil extending from the tab and leave an exposed area of adhesive around the circumference of the spacing sheet for adhering the electrodes to the skin of the patient. The overlapped portion of the spacing sheet and foil creates an opening into the interior of the electrode after it is placed on the skin for injection of a liquid electrolyte. The electrode assembly for electrical stimulation of the. muscle complex includes two input electrodes placed on each side of the face and a dispersal electrode. The planar sheet material of the two input electrodes each has a notch adjacent the projecting tab adapted to fit under the respective earlobes of the patient. The notch is located so that the electrode is correctly placed for electrical stimulation of the fifth and seventh cranial nerves. Conductive means leading from a pulse generating apparatus are electrically connected to each of the electrodes by means of clips attached to the respective tabs.
It is the primary objection of this invention to provide disposable electrodes for. electrical stimulation of nerves and muscles through the skin.
It is a further object of this invention to provide a disposable electrode assembly for electrical stimulation of the facial muscles with a pulsing electrical current from a pulse generating apparatus.
It is a further object of this invention to provide a disposable electrode assembly which does not have restraining bands or straps.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a perspective view illustrating the position of the input electrodes on the sides of the face of a patient and a dispersal electrode on the cervical spine of the patient, each of the electrodes being connected through electrical conductive means to a pulse generating apparatus;
FIG. 2 is a front elevation of the adhesive coated surface of one of the input electrodes of this invention;
FIG. 3 is a cross-sectional view of the disposable electrode of FIG. 2 prior to its separation from a backing sheet;
FIG. 4 is a cross-sectional view of the disposable electrode of FIG. 2 adhered to the skin of the patient;
FIG. 5 is a cross-sectional view of the disposable electrode of FIG. 2 illustrating the electrode adhered to the skin of the patient and an electrolyte being injected into the interior pocket formed by the spacing sheet; and
FIG. 6 is a cross-sectional view of the disposable electrode of FIG. 2 showing electrically conductive means secured to the tab extending from the upper end of the electrode.
DESCRIPTION OF THE PREFERRED EMBODIMENTS The disposable electrode assembly of this invention is primarily useful in electrical stimulation of the mus cle complex through the fifth and seventh cranial nerves with resultant involuntary closure of the human mandible. The method of producing a muscularly balanced closure of the human mandible through electrical stimulation of the masticatory and facial muscles is described in detail in copending application Ser. No. 855,480, filed Sept. 5, 1970, now US. Pat. No. 3,593,422, and entitled Method of Producing a Muscularly Balanced Closure of the Human Mandible. The copending application describes a method of involuntarily closing the human mandible for various clinical objectives by electrically stimulating the muscles enervated by the fifth and seventh cranial nerves on both sides of the face. Stimulation results in coordinated contraction of the masticatory and facial muscles controlling opening and closing of the mandible. In practicing the method described for various clinical objectives, it is essential that the input electrodes placed on each side of the face be in continuous electrical contact so that the current flow through the skin is not interrupted at any time. If the current flow through the skin varies, it gives rise to unequal stimulation of the muscles on either side of the face and is unacceptable.
FIG. ll of the drawings shows a disposable input electrode and common dispersal electrode 20, secured in specified locations to the head of a patient. The input electrodes are adhesively secured to the skin of the patient, one on each side of the face in a position for electrical stimulation of the fifth and seventh nerves through the mandibular notch. This is done most effectively if the electrodes are located over the opening in the bones of the face called the mandibular notch. In order to correctly position the input electrodes on the face of the patient, the input electrodes are formed with a shoulder portion or notch which is positioned directly under the respective earlobe of the patient. The notch locates the correct position of the electrode on the side of the patients face.
Each of the input electrodes comprises a flexible, planar sheet material of vinyl plastic or other suitable nonconductive material 12 having a tab portion 14 extending outwardly from the circumference of the sheet. Although the input and dispersal electrodes are illustrated as being generally rectangular or square, the particular shape is not of any significance. Preferably, however, the input electrodes are formed with a notch or shoulder portion 16 to correctly locate the position of the input electrodes on each side of the patients face. The notch should be located under the lobe of the ear such that the central portion of the electrode is directly over the mandibular notch of the patient on each side of the face for electrical stimulation of the fifth and seventh cranial nerves. One side of each of the electrodes is coated with a commercially available and conventional skin adhesive. The entire surface is coated with the adhesive.
A strip of electrically conductive foil 18 is adhered to the adhesive-coated tabular surface 14 of the nonconductive sheet material and extends past the tab toward the central portion of the sheet material. A planar, flexible, spacing sheet 19 is adhered to the adhesive-coated surface of the electrode so that it overlaps the foil extending from the tab 14. The surface area of the spacing sheet 19 is smaller than that of sheet material 12 to leave an exposed area of adhesive around the outer circumference of the sheet 19 for adhering the electrode to the skin of the patient. The spacing sheet should be porous for absorption of a liquid electrolyte. A material which has been found to work satisfactorily and which is economical is a fine mesh screen of glass fiber which is both electrically nonconductive and capable of holding the electrolyte satisfactorily.
For shipping and storage a set of electrodes which includes two input electrodes 10 and a dispersal elec trode 20 is adhered to a backing sheet 30 of conventional character. When it is desired to use the electrodes, the facial skin is scrubbed with alcohol or other material around the earlobes and the nape of the neck to remove skin oils and makeup. The electrodes are peeled from the backing sheet 30 by holding the tab portion 14 and peeling it away from the backing sheet. The input electrodes which are marked right and left are applied on each side of the face of the patient with the notch portion 16 directly under the earlobe. The adhesive coated sheet 12 is pressed firmly against the skin to adhere it. The dispersal electrode is applied similarly and is preferably centered at the nape of the neck directly under the hairline. The tab portion of each of the input electrodes is then bent back to reveal an opening or pocket in the interior of the electrode where the spacing sheet is located. An electrolyte, preferably in gel form, is injected, as illustrated in FIG. 5, into the pocket. The electrolyte is held by the porous spacing sheet. The opening is partially filled and, after filling, is gently pressed to spread the gel so that good electrical contact between the skin and the metallic tab extending from the tab portion is insured. Clips connected to electrically conductive wires are attached to the tab portion of each of the electrodes and to the pulse generating apparatus. When the clips are at tached, the apparatus is ready for use. After use the electrodes are removed by detaching the clips, stripping them from the skin and disposing of them.
The electrodes described are economically manufactured, easy to use, and have many advantages over those in common use. Although described with particular reference to electrical stimulation of the facial and mandibular muscles, the electrodes may be used in any application where electrical stimulation through the skin is necessary or where electrical pickup through the skin of the patient is needed.
The embodiments of the invention in which a particular property or privilege is claimed are defined as follows:
1 Disposable electrodes for application directly to the skin of a patient comprising:
a flexible, electrically non-conductive, planar, synthetic plastic sheet having a thickness ranging from 1 to 3 mils. coated with a skin adhesive on one side thereof, the plastic sheet having a projecting tab extending from one edge of the sheet for connection to a flexible lead wire and a shoulder portion extending outwardly from an adjacent edge of the planar sheet for fitting under the earlobe of the patient to correctly place the electrode on the face of the patient for electrical stimulation of the fifth and seventh cranial nerves through the mandibular notch region, r I
an electrically conductive foil sheet adhered to the adhesive-coated projecting tab and extending part way across the central area of the planar sheet, and
a flexible, fine mesh, electrically non-conductive screen material adhered to the adhesive-coated surface thereof having a surface area smaller than the surface area of the non-conductive planar sheet and overlapping the portion of the foil sheet extending across the central area of the planar sheet from the tab and leaving an exposed area of adhehesive coated surface around the remaining edges sive-coated surface around the remaining edges thereof for adhering the adhesive-coated planar thereof for adhering the adhesive-coated sheet to sheet to the skin of the patient, the overlapped porthe Skin of the patient, the overlapped por ion of tion of the screen material and foil creating a the Screen material and foil creating a Pocket when 5 pocket when the electrode is adhered to the skin of the electrode assembly is adhered to the skin of the h patient f i j i of a l l t l P h for injection of a gel electrolyte" a common dispersal electrode comprising: (1 a flexi- A p electrode assembly for electrical ble, electrically nonconductive, planar plastic sheet stimulation of facial muscles with a pulsing electrical having an adhesive coating one Side th f cumin? m a Pulse generating apparatus fomprisihgi adapted to be secured to the skin of the patient, the a pair of mput electrodes, each of the input elecsheet having a projecting tab extending from one trodes comprising: (1) a flexible, electrically nonconductive, planar, synthetic plastic sheet having a thickness ranging from 1 to 3 mils. and having an edge thereof for connection to a flexible lead wire, (2) an electrically conductive foil sheet adhered to the adhesive coated surface of the projecting tab :ddhe,swe.coa.tmg on one F thereof the sheet hav- 5 and extending part way across the central area of mg a pro ecting tab extending from one edge of the the lam sheet (3) a lam" flexible fine mesh sheet for connection to a flexible lead wire and a p shoulder portion extending outwardly from an electrically non-conductive screen material havmg jacent edge of the sheet for fitting under the earalsurfacfi area i ,2 E h lobe of the patient to correctly place the electrode p anar s eet f over appmg e porno" O t e on the face of the patient for electrical stimulation Sheet extendmg across the central area of the i of the fifth and seventh cranial nerves through the sheet to an exposed area of adhesfve mandibular notch region; (2) an electrically conaround the remahmg f for adhering ductive foil sheet adhered to the adhesive coated the electmhe to the 8km of the P h the surface of the projecting tab and extending part pp? P of the Screen matenai and fol] way across the central area of the plastic sheet; (3) creahhg a P Y theehectfode ls h f to a flexbile, fine mesh, electrically nonconductive the 5km of the P for lhlechoh of a hqhld gel screen material having a surface area smaller than electrolyte thereln, and the surface area of the nonconductive plasti sh et flexible lead wires connected to the dispersal elecand overlapping the portion of the foil sheet extrode and the input electrodes: for receiving current tending across the central area of the planar sheet from a pulse generating apparatus. from the tab and leaving an exposed area of the ad-

Claims (1)

  1. 2. A disposable electrode assembly for electrical stimulation of facial muscles with a pulsing electrical current from a pulse generating apparatus comprising: a pair of input electrodes, each of the input electrodes comprising: (1) a flexible, electrically non-conductive, planAr, synthetic plastic sheet having a thickness ranging from 1 to 3 mils. and having an adhesive coating on one side thereof, the sheet having a projecting tab extending from one edge of the sheet for connection to a flexible lead wire and a shoulder portion extending outwardly from an adjacent edge of the sheet for fitting under the earlobe of the patient to correctly place the electrode on the face of the patient for electrical stimulation of the fifth and seventh cranial nerves through the mandibular notch region; (2) an electrically conductive foil sheet adhered to the adhesive coated surface of the projecting tab and extending part way across the central area of the plastic sheet; (3) a flexbile, fine mesh, electrically nonconductive screen material having a surface area smaller than the surface area of the nonconductive plastic sheet and overlapping the portion of the foil sheet extending across the central area of the planar sheet from the tab and leaving an exposed area of the adhesive coated surface around the remaining edges thereof for adhering the adhesive-coated planar sheet to the skin of the patient, the overlapped portion of the screen material and foil creating a pocket when the electrode is adhered to the skin of the patient for injection of a gel electrolyte: a common dispersal electrode comprising: (1) a flexible, electrically nonconductive, planar plastic sheet having an adhesive coating on one side thereof adapted to be secured to the skin of the patient, the sheet having a projecting tab extending from one edge thereof for connection to a flexible lead wire, (2) an electrically conductive foil sheet adhered to the adhesive coated surface of the projecting tab and extending part way across the central area of the planar sheet, (3) a planar, flexible, fine mesh, electrically non-conductive screen material having a surface area smaller than the surface area of the planar sheet and overlapping the portion of the foil sheet extending across the central area of the planar sheet to leave an exposed area of adhesive around the remaining edges thereof for adhering the electrode to the skin of the patient, the overlapped portion of the screen material and the foil creating a pocket when the electrode is adhered to the skin of the patient for injection of a liquid gel electrolyte therein, and flexible lead wires connected to the dispersal electrode and the input electrodes for receiving current from a pulse generating apparatus.
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Cited By (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881495A (en) * 1973-08-08 1975-05-06 Anthony N Pannozzo Method of nerve therapy using trapezoidal pulses
US3900020A (en) * 1974-05-02 1975-08-19 Chuck Lock Electronic acupuncture device
US3977392A (en) * 1975-04-21 1976-08-31 Eastprint, Inc. Medical electrode
FR2345981A1 (en) * 1976-03-29 1977-10-28 Rasmussen Steen ELECTRODE FOR ELECTROMEDICAL USE, TO BE DISCARDED AFTER USE AND METHOD FOR MANUFACTURING A SET OF SUCH ELECTRODES
US4088138A (en) * 1974-01-02 1978-05-09 Cardiac Resuscitator Corp. Cardiac resuscitator and monitoring apparatus
US4092985A (en) * 1974-11-25 1978-06-06 John George Kaufman Body electrode for electro-medical use
USRE30750E (en) * 1972-05-15 1981-09-29 Cardiac Resuscitator Corporation Cardiac resuscitator and monitoring apparatus
US4319579A (en) * 1979-06-21 1982-03-16 Ndm Corporation Reusable medical electrode having disposable electrolyte carrier
US4543958A (en) * 1979-04-30 1985-10-01 Ndm Corporation Medical electrode assembly
US4584962A (en) * 1979-04-30 1986-04-29 Ndm Corporation Medical electrodes and dispensing conditioner therefor
EP0181057A2 (en) * 1984-10-08 1986-05-14 Nitto Denko Corporation Biomedical electrode
US4590089A (en) * 1979-04-30 1986-05-20 Ndm Corporation Medical electrodes and dispensing conditioner therefor
US4595010A (en) * 1984-03-12 1986-06-17 Bio-Research Associates, Inc. Electrical muscle stimulator
US4635641A (en) * 1985-10-16 1987-01-13 Murray Electronics Associates Limited Multi-element electrode
US4649923A (en) * 1985-10-16 1987-03-17 Murray Electronics Associates Limited Temperature indicating electrotherapy electrode
US4669468A (en) * 1979-06-15 1987-06-02 American Hospital Supply Corporation Capacitively coupled indifferent electrode
US4674511A (en) * 1979-04-30 1987-06-23 American Hospital Supply Corporation Medical electrode
US4700710A (en) * 1985-03-12 1987-10-20 Murray Electronics Associates Limited Partnership Apertured adhesively applied body electrode apparatus and method
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
USRE32724E (en) * 1979-06-21 1988-08-02 American Hospital Supply Corporation Reusable medical electrode having disposable electrolyte carrier
GB2200284A (en) * 1986-12-31 1988-08-03 Hayashibara Ken Electrode for skin treatment
US4786277A (en) * 1986-11-21 1988-11-22 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation
US4798208A (en) * 1987-12-09 1989-01-17 Faasse Jr Adrian L Diagnostic electrode
US4832036A (en) * 1985-05-13 1989-05-23 Baxter International Inc. Medical electrode
US4838273A (en) * 1979-04-30 1989-06-13 Baxter International Inc. Medical electrode
US5086786A (en) * 1986-06-27 1992-02-11 Kureha Kagaku Kogyo Kabushiki Kaisha Electrode device for heating tumor in endotract organ
US5566671A (en) * 1994-05-23 1996-10-22 Lyons; Chad Medical acoustic sensor receptacle
US5566672A (en) * 1994-01-03 1996-10-22 Labeltape Meditect, Inc. Biomedical electrode
US5928141A (en) * 1995-08-01 1999-07-27 Castelli; Arrigo Electrode for detecting an electric biological signal, in particular an electrocardiographic signal
US6345196B1 (en) 1998-12-30 2002-02-05 Arrigo Castelli Electrode for detecting an electric biological signal, in particular an electrocardiographic signal, and electrocardiograph employing such an electrode
DE10307446B4 (en) * 2002-02-22 2008-05-29 Tyco Healthcare Deutschland Manufacturing Gmbh Biomedical electrode
EP2076313A2 (en) * 2006-10-16 2009-07-08 The Regents of the University of California Gels with predetermined conductivity used in irreversible electroporation of tissue
US20090210028A1 (en) * 2008-02-20 2009-08-20 Stx-Med Sprl Device for the electrotherapeutic treatment of tension headaches
US20100137940A1 (en) * 1997-07-21 2010-06-03 Levin Bruce H Method for Directed Intranasal Administration of a Composition
WO2010067145A1 (en) * 2008-12-11 2010-06-17 Bmr Research & Development Limited Facial stimulation apparatus
US20110190848A1 (en) * 2007-07-11 2011-08-04 Campbell Russell A Method and Apparatus for Laryngeal Elevator Musculature Rehabilitation
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
CN106455983A (en) * 2014-03-17 2017-02-22 奥地利科技研究所有限责任公司 Device for determining the state of a person skin
US9598691B2 (en) 2008-04-29 2017-03-21 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US9757196B2 (en) 2011-09-28 2017-09-12 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9764145B2 (en) 2009-05-28 2017-09-19 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10154874B2 (en) 2008-04-29 2018-12-18 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using irreversible electroporation
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10245105B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Electroporation with cooling to treat tissue
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10292755B2 (en) 2009-04-09 2019-05-21 Virginia Tech Intellectual Properties, Inc. High frequency electroporation for cancer therapy
US10335224B2 (en) 2000-08-17 2019-07-02 Angiodynamics, Inc. Method of destroying tissue cells by electroporation
US10463426B2 (en) 2001-08-13 2019-11-05 Angiodynamics, Inc. Method for treating a tubular anatomical structure
US10471254B2 (en) 2014-05-12 2019-11-12 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US10470822B2 (en) 2008-04-29 2019-11-12 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US10694972B2 (en) 2014-12-15 2020-06-30 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11433234B2 (en) 2017-05-19 2022-09-06 Cefaly Technology Sprl External trigeminal nerve stimulation for the acute non-invasive treatment of migraine attacks
US11453873B2 (en) 2008-04-29 2022-09-27 Virginia Tech Intellectual Properties, Inc. Methods for delivery of biphasic electrical pulses for non-thermal ablation
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US11723710B2 (en) 2016-11-17 2023-08-15 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11931096B2 (en) 2010-10-13 2024-03-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
US11952568B2 (en) 2019-04-05 2024-04-09 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of biphasic electrical pulses for non-thermal ablation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151619A (en) * 1961-07-17 1964-10-06 Spacelab Inc Electrode for electromedical equipment
US3447537A (en) * 1967-10-31 1969-06-03 Intern Fonovisione Spa Soc Facial mask
US3487827A (en) * 1968-01-24 1970-01-06 Physio Control Corp Electrode for electromedical equipment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151619A (en) * 1961-07-17 1964-10-06 Spacelab Inc Electrode for electromedical equipment
US3447537A (en) * 1967-10-31 1969-06-03 Intern Fonovisione Spa Soc Facial mask
US3487827A (en) * 1968-01-24 1970-01-06 Physio Control Corp Electrode for electromedical equipment

Cited By (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30750E (en) * 1972-05-15 1981-09-29 Cardiac Resuscitator Corporation Cardiac resuscitator and monitoring apparatus
US3881495A (en) * 1973-08-08 1975-05-06 Anthony N Pannozzo Method of nerve therapy using trapezoidal pulses
US4088138A (en) * 1974-01-02 1978-05-09 Cardiac Resuscitator Corp. Cardiac resuscitator and monitoring apparatus
US3900020A (en) * 1974-05-02 1975-08-19 Chuck Lock Electronic acupuncture device
US4092985A (en) * 1974-11-25 1978-06-06 John George Kaufman Body electrode for electro-medical use
US3977392A (en) * 1975-04-21 1976-08-31 Eastprint, Inc. Medical electrode
US4155354A (en) * 1976-03-29 1979-05-22 Rasmussen Steen B Disposable electromedical electrode and a set of such electrodes
FR2345981A1 (en) * 1976-03-29 1977-10-28 Rasmussen Steen ELECTRODE FOR ELECTROMEDICAL USE, TO BE DISCARDED AFTER USE AND METHOD FOR MANUFACTURING A SET OF SUCH ELECTRODES
US4838273A (en) * 1979-04-30 1989-06-13 Baxter International Inc. Medical electrode
US4543958A (en) * 1979-04-30 1985-10-01 Ndm Corporation Medical electrode assembly
US4584962A (en) * 1979-04-30 1986-04-29 Ndm Corporation Medical electrodes and dispensing conditioner therefor
US4590089A (en) * 1979-04-30 1986-05-20 Ndm Corporation Medical electrodes and dispensing conditioner therefor
US4674511A (en) * 1979-04-30 1987-06-23 American Hospital Supply Corporation Medical electrode
US4669468A (en) * 1979-06-15 1987-06-02 American Hospital Supply Corporation Capacitively coupled indifferent electrode
USRE32724E (en) * 1979-06-21 1988-08-02 American Hospital Supply Corporation Reusable medical electrode having disposable electrolyte carrier
US4319579A (en) * 1979-06-21 1982-03-16 Ndm Corporation Reusable medical electrode having disposable electrolyte carrier
US4595010A (en) * 1984-03-12 1986-06-17 Bio-Research Associates, Inc. Electrical muscle stimulator
EP0181057A3 (en) * 1984-10-08 1988-07-20 Nitto Electric Industrial Co., Ltd. Biomedical electrode
EP0181057A2 (en) * 1984-10-08 1986-05-14 Nitto Denko Corporation Biomedical electrode
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4700710A (en) * 1985-03-12 1987-10-20 Murray Electronics Associates Limited Partnership Apertured adhesively applied body electrode apparatus and method
US4832036A (en) * 1985-05-13 1989-05-23 Baxter International Inc. Medical electrode
US4649923A (en) * 1985-10-16 1987-03-17 Murray Electronics Associates Limited Temperature indicating electrotherapy electrode
US4635641A (en) * 1985-10-16 1987-01-13 Murray Electronics Associates Limited Multi-element electrode
US5086786A (en) * 1986-06-27 1992-02-11 Kureha Kagaku Kogyo Kabushiki Kaisha Electrode device for heating tumor in endotract organ
US4786277A (en) * 1986-11-21 1988-11-22 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation
GB2200284A (en) * 1986-12-31 1988-08-03 Hayashibara Ken Electrode for skin treatment
GB2200284B (en) * 1986-12-31 1991-01-02 Hayashibara Ken Electrode for skin treatment
US4798208A (en) * 1987-12-09 1989-01-17 Faasse Jr Adrian L Diagnostic electrode
US5566672A (en) * 1994-01-03 1996-10-22 Labeltape Meditect, Inc. Biomedical electrode
US5566671A (en) * 1994-05-23 1996-10-22 Lyons; Chad Medical acoustic sensor receptacle
US5928141A (en) * 1995-08-01 1999-07-27 Castelli; Arrigo Electrode for detecting an electric biological signal, in particular an electrocardiographic signal
US8224438B2 (en) 1997-07-21 2012-07-17 Levin Bruce H Method for directed intranasal administration of a composition
US9302096B2 (en) 1997-07-21 2016-04-05 Bruce H. Levin Apparatus for treating cerebral neurovascular disorders including headaches by neural stimulation
US9381349B2 (en) 1997-07-21 2016-07-05 Bhl Patent Holdings Llc Apparatus for treating cerebral neurovascular disorders including headaches by neural stimulation
US20100137940A1 (en) * 1997-07-21 2010-06-03 Levin Bruce H Method for Directed Intranasal Administration of a Composition
US6345196B1 (en) 1998-12-30 2002-02-05 Arrigo Castelli Electrode for detecting an electric biological signal, in particular an electrocardiographic signal, and electrocardiograph employing such an electrode
US10335224B2 (en) 2000-08-17 2019-07-02 Angiodynamics, Inc. Method of destroying tissue cells by electroporation
US10463426B2 (en) 2001-08-13 2019-11-05 Angiodynamics, Inc. Method for treating a tubular anatomical structure
DE10307446B4 (en) * 2002-02-22 2008-05-29 Tyco Healthcare Deutschland Manufacturing Gmbh Biomedical electrode
EP2076313A2 (en) * 2006-10-16 2009-07-08 The Regents of the University of California Gels with predetermined conductivity used in irreversible electroporation of tissue
EP2076313A4 (en) * 2006-10-16 2012-07-25 Univ California Gels with predetermined conductivity used in irreversible electroporation of tissue
US8348921B2 (en) 2006-10-16 2013-01-08 The Regents Of The University Of California Gels with predetermined conductivity used in electroporation of tissue
US20110190848A1 (en) * 2007-07-11 2011-08-04 Campbell Russell A Method and Apparatus for Laryngeal Elevator Musculature Rehabilitation
US9031659B2 (en) * 2007-07-11 2015-05-12 Ampcare, Llc Method and apparatus for laryngeal elevator musculature rehabilitation
US8428734B2 (en) 2008-02-20 2013-04-23 Stx-Med Sprl Device for the electrotherapeutic treatment of tension headaches
EP2092951A1 (en) * 2008-02-20 2009-08-26 Stx-Med Sprl Device for electrotherapeutical treatment of tension headaches
US20090210028A1 (en) * 2008-02-20 2009-08-20 Stx-Med Sprl Device for the electrotherapeutic treatment of tension headaches
US10470822B2 (en) 2008-04-29 2019-11-12 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US11737810B2 (en) 2008-04-29 2023-08-29 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using electroporation
US11453873B2 (en) 2008-04-29 2022-09-27 Virginia Tech Intellectual Properties, Inc. Methods for delivery of biphasic electrical pulses for non-thermal ablation
US11655466B2 (en) 2008-04-29 2023-05-23 Virginia Tech Intellectual Properties, Inc. Methods of reducing adverse effects of non-thermal ablation
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US10959772B2 (en) 2008-04-29 2021-03-30 Virginia Tech Intellectual Properties, Inc. Blood-brain barrier disruption using electrical energy
US10828086B2 (en) 2008-04-29 2020-11-10 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using irreversible electroporation
US10828085B2 (en) 2008-04-29 2020-11-10 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using irreversible electroporation
US11607271B2 (en) 2008-04-29 2023-03-21 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US10537379B2 (en) 2008-04-29 2020-01-21 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US11890046B2 (en) 2008-04-29 2024-02-06 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10286108B2 (en) 2008-04-29 2019-05-14 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US10245105B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Electroporation with cooling to treat tissue
US9598691B2 (en) 2008-04-29 2017-03-21 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10154874B2 (en) 2008-04-29 2018-12-18 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using irreversible electroporation
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8682452B2 (en) 2008-12-11 2014-03-25 Bio-Medical Research Limited Facial stimulation apparatus
US20100152810A1 (en) * 2008-12-11 2010-06-17 Conor Minogue Facial stimulation apparatus
WO2010067145A1 (en) * 2008-12-11 2010-06-17 Bmr Research & Development Limited Facial stimulation apparatus
KR101196944B1 (en) 2008-12-11 2012-11-05 바이오-메디컬 리서치 리미티드 Facial stimulation apparatus
AU2008365106B2 (en) * 2008-12-11 2015-02-05 Bio-Medical Research Limited Facial stimulation apparatus
GB2479092A (en) * 2008-12-11 2011-09-28 Bmr Res & Dev Ltd Facial stimulation apparatus
CN102316926A (en) * 2008-12-11 2012-01-11 生物医药研究有限公司 Facial stimulation apparatus
CN102316926B (en) * 2008-12-11 2015-06-17 生物医药研究有限公司 Facial stimulation apparatus
EP2198915A1 (en) * 2008-12-11 2010-06-23 BMR Research & Development Limited Facial stimulation apparatus
GB2479092B (en) * 2008-12-11 2013-08-07 Bio Medical Res Ltd Facial stimulation apparatus
US8781574B2 (en) 2008-12-29 2014-07-15 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9554694B2 (en) 2008-12-29 2017-01-31 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US10292755B2 (en) 2009-04-09 2019-05-21 Virginia Tech Intellectual Properties, Inc. High frequency electroporation for cancer therapy
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US8886325B2 (en) 2009-04-22 2014-11-11 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9764145B2 (en) 2009-05-28 2017-09-19 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US11707629B2 (en) 2009-05-28 2023-07-25 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US11931096B2 (en) 2010-10-13 2024-03-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US11779395B2 (en) 2011-09-28 2023-10-10 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9757196B2 (en) 2011-09-28 2017-09-12 Angiodynamics, Inc. Multiple treatment zone ablation probe
CN106455983A (en) * 2014-03-17 2017-02-22 奥地利科技研究所有限责任公司 Device for determining the state of a person skin
US20170095208A1 (en) * 2014-03-17 2017-04-06 Ait Austrian Institute Of Technology Gmbh Device For Determining The Condition Of A Person's Skin
CN106455983B (en) * 2014-03-17 2020-06-19 奥地利科技研究所有限责任公司 Device for determining the condition of human skin
US11406820B2 (en) 2014-05-12 2022-08-09 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US10471254B2 (en) 2014-05-12 2019-11-12 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US10694972B2 (en) 2014-12-15 2020-06-30 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US11903690B2 (en) 2014-12-15 2024-02-20 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US11723710B2 (en) 2016-11-17 2023-08-15 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US11433234B2 (en) 2017-05-19 2022-09-06 Cefaly Technology Sprl External trigeminal nerve stimulation for the acute non-invasive treatment of migraine attacks
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11952568B2 (en) 2019-04-05 2024-04-09 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of biphasic electrical pulses for non-thermal ablation
US11950835B2 (en) 2020-06-29 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy

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