US5073646A - Substituted 1-diphenylmethyl azetidines - Google Patents

Substituted 1-diphenylmethyl azetidines Download PDF

Info

Publication number: US5073646A
Authority: US; United States
Prior art keywords: diphenylmethyl; radical; sub; methylazetidine; amino
Prior art date: 1989-06-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

US07/541,056

Other languages

English (en)

Inventor

Augusto C. Pinol

Jordi F. Constansa

Juan P. Corominas

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Esteve Pharmaceuticals SA

Original Assignee

Laboratorios del Dr Esteve SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-29

Filing date

1990-06-20

Publication date

1991-12-17

1990-06-20 Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA

1990-08-01 Assigned to LABORATORIOS DEL DR. ESTEVE, S.A. reassignment LABORATORIOS DEL DR. ESTEVE, S.A. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: CONSTANSA, JORDI F., COROMINAS, JUAN P., PINOL, AUGUSTO C.

1991-12-17 Application granted granted Critical

1991-12-17 Publication of US5073646A publication Critical patent/US5073646A/en

2010-06-20 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

US07/541,056 1989-06-29 1990-06-20 Substituted 1-diphenylmethyl azetidines Expired - Lifetime US5073646A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8908696		1989-06-29
FR898908696A FR2649100B1 (fr)	1989-06-29	1989-06-29	Nouvelles azetidines, leur preparation et leur application comme intermediaires pour la preparation de composes avec activite antimicrobienne

Publications (1)

Publication Number	Publication Date
US5073646A true US5073646A (en)	1991-12-17

Family

ID=9383263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
US07/541,056 Expired - Lifetime US5073646A (en)	1989-06-29	1990-06-20	Substituted 1-diphenylmethyl azetidines

Country Status (18)

Country	Link
US (1)	US5073646A (ja)
EP (1)	EP0406112B1 (ja)
JP (1)	JPH0338565A (ja)
KR (1)	KR940005012B1 (ja)
AT (1)	ATE116293T1 (ja)
CA (1)	CA2020097C (ja)
DD (1)	DD298911A5 (ja)
DE (1)	DE69015471T2 (ja)
DK (1)	DK0406112T3 (ja)
ES (1)	ES2029160A6 (ja)
FR (1)	FR2649100B1 (ja)
GR (1)	GR3015040T3 (ja)
HU (2)	HU208808B (ja)
NO (1)	NO175778C (ja)
PT (1)	PT94535B (ja)
RU (1)	RU2002739C1 (ja)
YU (1)	YU48412B (ja)
ZA (1)	ZA905044B (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6479479B2 (en)	2000-03-03	2002-11-12	Aventis Pharma S.A.	Azetidine derivatives, their preparation and pharmaceutical compositions containing them
US20050182041A1 (en) *	2004-02-16	2005-08-18	Altisen Rosa C.	Substituted Azetidine compounds, their preparation and use as medicaments
US20050187208A1 (en) *	2004-02-17	2005-08-25	Rosa Cuberes Altisen	Substituted Azetidine compounds, their preparation and use as medicaments
WO2005077897A1 (en)	2004-02-17	2005-08-25	Laboratorios Del Dr. Esteve S.A.	Substituted azetidine compounds, their preparation and use as medicaments

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2676445B1 (fr) *	1991-05-16	1995-02-03	Esteve Labor Dr	Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments.
WO1999019297A1 (en) *	1997-10-15	1999-04-22	Coelacanth Chemical Corporation	Synthesis of azetidine derivatives
WO2000063168A1 (en) *	1999-04-16	2000-10-26	Coelacanth Chemical Corporation	Synthesis of azetidine derivatives
FR2805810B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
FR2805818B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
US6566356B2 (en)	2000-03-03	2003-05-20	Aventis Pharma S.A.	Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
FR2805817B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
KR100704768B1 (ko) *	2000-12-07	2007-04-09	한라공조주식회사	수액기 및 바이패스 유로를 갖는 응축기
CN1668887A (zh)	2002-06-18	2005-09-14	昭和电工株式会社	整体式热交换器

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2150816A1 (ja) *	1971-08-21	1973-04-13	Teikoku Hormone Mfg Co Ltd
US3929755A (en) *	1973-06-01	1975-12-30	Us Agriculture	Pyrolyzed rosin products as synthetic rubber tackifiers
EP0153163A2 (en) *	1984-02-17	1985-08-28	Warner-Lambert Company	7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds
EP0155870A1 (fr) *	1984-02-27	1985-09-25	Sanofi	3-aminoazétidine, ses sels, procédé pour leur préparation et intermédiaires de synthèse
DE3627246A1 (de) *	1986-08-12	1988-02-18	Bayer Ag	Neue azetidinaniline sowie ein verfahren zu deren herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS49109369A (ja) *	1973-03-02	1974-10-17
BE860705A (fr) *	1976-11-12	1978-05-10	Scherico Ltd	Compositions antipsoriatiques
GB8328253D0 (en) *	1983-10-21	1983-11-23	Shell Int Research	Substituted azetidine derivatives

1989
- 1989-06-29 FR FR898908696A patent/FR2649100B1/fr not_active Expired - Fee Related
1990
- 1990-06-20 US US07/541,056 patent/US5073646A/en not_active Expired - Lifetime
- 1990-06-22 YU YU122890A patent/YU48412B/sh unknown
- 1990-06-27 NO NO902866A patent/NO175778C/no unknown
- 1990-06-28 RU SU904830563A patent/RU2002739C1/ru not_active IP Right Cessation
- 1990-06-28 PT PT94535A patent/PT94535B/pt not_active IP Right Cessation
- 1990-06-28 AT AT90401860T patent/ATE116293T1/de not_active IP Right Cessation
- 1990-06-28 DK DK90401860.3T patent/DK0406112T3/da active
- 1990-06-28 HU HU904024A patent/HU208808B/hu not_active IP Right Cessation
- 1990-06-28 ZA ZA905044A patent/ZA905044B/xx unknown
- 1990-06-28 CA CA002020097A patent/CA2020097C/en not_active Expired - Fee Related
- 1990-06-28 DE DE69015471T patent/DE69015471T2/de not_active Expired - Fee Related
- 1990-06-28 EP EP90401860A patent/EP0406112B1/fr not_active Expired - Lifetime
- 1990-06-28 DD DD90342262A patent/DD298911A5/de unknown
- 1990-06-29 ES ES9001914A patent/ES2029160A6/es not_active Expired - Fee Related
- 1990-06-29 JP JP2174318A patent/JPH0338565A/ja active Pending
- 1990-06-29 KR KR1019900009718A patent/KR940005012B1/ko not_active IP Right Cessation
1994
- 1994-07-13 HU HU94P/P00012P patent/HU210068A9/hu unknown
1995
- 1995-02-09 GR GR950400272T patent/GR3015040T3/el unknown

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2150816A1 (ja) *	1971-08-21	1973-04-13	Teikoku Hormone Mfg Co Ltd
US3929755A (en) *	1973-06-01	1975-12-30	Us Agriculture	Pyrolyzed rosin products as synthetic rubber tackifiers
EP0153163A2 (en) *	1984-02-17	1985-08-28	Warner-Lambert Company	7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds
EP0155870A1 (fr) *	1984-02-27	1985-09-25	Sanofi	3-aminoazétidine, ses sels, procédé pour leur préparation et intermédiaires de synthèse
US4822895A (en) *	1984-02-27	1989-04-18	Societe Anonyme - Sanofi	3-aminoazetidine, its salts and intermediates of synthesis
DE3627246A1 (de) *	1986-08-12	1988-02-18	Bayer Ag	Neue azetidinaniline sowie ein verfahren zu deren herstellung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA 78: 135964y (1975). *
CA 82(5): 31187p (1973). *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6479479B2 (en)	2000-03-03	2002-11-12	Aventis Pharma S.A.	Azetidine derivatives, their preparation and pharmaceutical compositions containing them
US20050130953A1 (en) *	2000-03-03	2005-06-16	Aventis Pharma S.A.	Pharmacological uses of azetidine derivatives
US7741316B2 (en)	2000-03-03	2010-06-22	Aventis Pharma S.A.	Pharmacological uses of azetidine derivatives
US20050182041A1 (en) *	2004-02-16	2005-08-18	Altisen Rosa C.	Substituted Azetidine compounds, their preparation and use as medicaments
US7232812B2 (en)	2004-02-16	2007-06-19	Laboratorios De Dr. Esteve S.A.	Substituted azetidine compounds, their preparation and use as medicaments
US20050187208A1 (en) *	2004-02-17	2005-08-25	Rosa Cuberes Altisen	Substituted Azetidine compounds, their preparation and use as medicaments
WO2005077897A1 (en)	2004-02-17	2005-08-25	Laboratorios Del Dr. Esteve S.A.	Substituted azetidine compounds, their preparation and use as medicaments
US20070066587A1 (en) *	2004-02-17	2007-03-22	Laboratorios Del Dr. Esteve S.A	Substituted azetidine compounds, their preparation and use as medicaments

Also Published As

Publication number	Publication date
NO175778B (no)	1994-08-29
FR2649100A1 (fr)	1991-01-04
NO902866D0 (no)	1990-06-27
CA2020097A1 (en)	1990-12-30
JPH0338565A (ja)	1991-02-19
HU904024D0 (en)	1990-12-28
KR910000633A (ko)	1991-01-29
RU2002739C1 (ru)	1993-11-15
PT94535B (pt)	1997-02-28
DE69015471D1 (de)	1995-02-09
YU122890A (sh)	1992-12-21
FR2649100B1 (fr)	1994-03-04
DE69015471T2 (de)	1995-05-18
HU208808B (en)	1994-01-28
ZA905044B (en)	1991-05-29
ATE116293T1 (de)	1995-01-15
EP0406112B1 (fr)	1994-12-28
EP0406112A1 (fr)	1991-01-02
NO175778C (no)	1994-12-07
HUT54641A (en)	1991-03-28
GR3015040T3 (en)	1995-05-31
HU210068A9 (en)	1995-02-28
DK0406112T3 (da)	1995-04-03
PT94535A (pt)	1991-02-08
KR940005012B1 (ko)	1994-06-09
YU48412B (sh)	1998-07-10
ES2029160A6 (es)	1992-07-16
DD298911A5 (de)	1992-03-19
NO902866L (no)	1991-01-02
CA2020097C (en)	1997-09-30

Legal Events

Date	Code	Title	Description
1990-08-01	AS	Assignment	Owner name: LABORATORIOS DEL DR. ESTEVE, S.A., AV. MARE DE DEU Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:PINOL, AUGUSTO C.;CONSTANSA, JORDI F.;COROMINAS, JUAN P.;REEL/FRAME:005388/0803 Effective date: 19900529
1991-12-06	STCF	Information on status: patent grant	Free format text: PATENTED CASE
1994-12-07	FEPP	Fee payment procedure	Free format text: PAYOR NUMBER ASSIGNED (ORIGINAL EVENT CODE: ASPN); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY
1995-06-19	FPAY	Fee payment	Year of fee payment: 4
1999-06-21	FPAY	Fee payment	Year of fee payment: 8
1999-06-21	SULP	Surcharge for late payment
2003-05-30	FPAY	Fee payment	Year of fee payment: 12

Publication	Publication Date	Title
US5073646A (en)	1991-12-17	Substituted 1-diphenylmethyl azetidines
EP0219934B1 (en)	1991-10-30	Process for the preparation of aryl-piperidine esters
US5144042A (en)	1992-09-01	Process for preparing optically active 3-hydroxypyrrolidine derivatives
US5977381A (en)	1999-11-02	Process for making 3-amino-pyrolidine derivatives
US4895943A (en)	1990-01-23	Preparation of 1,4-diazabicyclo(3.2.2)nonane
Adamo et al.	1999	An Improved Resolution Of 2-Methyl Piperidine And Its Use in The Synthesis Of Homochiral Trans-2, 6-Dialkyl Piperidines
US4408063A (en)	1983-10-04	Preparation of epihalohydrin enantiomers
JP2002511434A5 (ja)	2005-04-07
US6057476A (en)	2000-05-02	Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers
KR870001922B1 (ko)	1987-10-22	이미다졸 유도체의 제조방법
AU622332B2 (en)	1992-04-02	New azetidines, their preparation and their application as intermediates for the preparation of compounds with antimicrobial activity
WO1988000190A1 (en)	1988-01-14	Optically active derivatives of glycidol
US4588824A (en)	1986-05-13	Preparation of epihalohydrin enantiomers
US4677214A (en)	1987-06-30	Intermediates for preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
FI88292C (fi)	1993-04-26	Foerfarande foer framstaellning av n-(sulfonylmetyl)formamider
KR100209298B1 (ko)	1999-07-15	새로운 아민고리 화합물
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SU549078A3 (ru)	1977-02-28	Способ получени производных 1фенокси-3-амино-пропан-2-ола или их солей
EP0120094B1 (en)	1989-04-19	Azetidinone compounds
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EP0274409A2 (en)	1988-07-13	Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives
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