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Numero di pubblicazioneWO1990013641 A1
Tipo di pubblicazioneRichiesta
Numero domandaPCT/US1990/002656
Data di pubblicazione11 nov 1990
Data di registrazione10 mag 1990
Data di priorità10 mag 1989
Pubblicato anche comeCA2055435A1, EP0471796A1, EP0471796A4
Numero di pubblicazionePCT/1990/2656, PCT/US/1990/002656, PCT/US/1990/02656, PCT/US/90/002656, PCT/US/90/02656, PCT/US1990/002656, PCT/US1990/02656, PCT/US1990002656, PCT/US199002656, PCT/US90/002656, PCT/US90/02656, PCT/US90002656, PCT/US9002656, WO 1990/013641 A1, WO 1990013641 A1, WO 1990013641A1, WO 9013641 A1, WO 9013641A1, WO-A1-1990013641, WO-A1-9013641, WO1990/013641A1, WO1990013641 A1, WO1990013641A1, WO9013641 A1, WO9013641A1
InventoriEli Gilboa, Bruce Sullenger
CandidatoSloan Kettering Inst Cancer
Esporta citazioneBiBTeX, EndNote, RefMan
Link esterni:  Patentscope, Espacenet
Cellules eucaryotes transformees de maniere stable comprenant un adn etranger susceptible d'etre transcrit sous la direction d'un promoteur pol iii
WO 1990013641 A1
Estratto
Une cellule eucaryote transformée de manière stable comprend un promoteur pol III et un ADN étranger susceptible d'être transcrit sous la direction du promoteur pol III. Un vecteur rétroviral comprend un ARN-t chimérique introduit dans la séquence répétitive teerminale longue en 3' du vecteur rétroviral.
Descrizione  disponibile in inglese
Rivendicazioni  disponibile in inglese
Citazioni di brevetti
Brevetto citato Data di registrazione Data di pubblicazione Candidato Titolo
US4497796 *8 dic 19825 feb 1985The Regents Of The University Of CaliforniaGene transfer in intact mammals
Citazioni diverse da brevetti
Riferimento
1 *Cell, Volume 43, published December 1985. J. TOBIAN, et al. "tRNA nuclear transport: defining the critical regions of human tRNA (i)(met) by point mutagenesis" pp. 415-422. see entire article.
2 *CHEMICAL ABSTRACTS, Volume 111, No. 13, issued 1989, September 25 (Columbus, Ohio, U.S.A.), E. GILBOA, et al. "Retroviral gene transfer: applications to human therapy" see page 110247, column 1, the Abstract No. 110249f, Adv. Exp. Biol. Med. 1988, 241 (Mol. Biol. Hemopoesis), 29-33 (Eng).
3 *Cold Spring Harbor Sym. on Mol. Biol., Volume LI. published 1986. A. MILLER, et al. "Transfer of genes into human somatic cells using retrovirus vectors" pp. 1013-1019. see entire article.
4 *EMBO J., Volume 6, Number 10, published October 1987. P. JENNINGS, et al. "Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III" pp. 3043-3047. see entire article.
5 *EMBO J., Volume 6, Number 2, published February 1987. N. TAKAMATSU, et al. "Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA" pp. 307-311. see entire article.
6 *J. Virol., Volume 63, Number 2, published February 1989. T. VON RUDEN, et al. "Inhibition of human T-cell leukemia virus type I replication in primary human T cells that express antisense RNA" pp. 677-682. see entire article.
7 *J. Virol., Volume 63, Number 3, published March 1989. M. HADZOPOULOU-CLADARAS, et al. "The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region" pp. 1265-1274 see entire article.
8 *Nature, Volume 323, published 25 September 1986. J. ZARLING, et al. "T-cell responses to human AIDS virus in macaques immunized with recombinant virus" pp. 344-346. see entire article.
9 *Nature, Volume 335, published 29 September 1988. A. FRIEDMAN, et al. "Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus" pp. 452-454. see entire article.
10 *Nature, Volume 335, published 29 September 1988. D. BALTIMORE "Intracellular Immunization" pp. 395-396. see entire article.
11 *Nucl. Acid. Res., Volume 11, Number 6, published 1983. D.JOLLY, et al. "Elements in the long terminal repeat of murine retroviruses stable transformation by thymidine kinase gene", pp. 1855-1872. see entire document.
12 *Nucl. Acid. Res., Volume 12, Number 2, published 1984. S. ADENIYI-JONES, et al. "Generation of long read-through transcripts in vivo and in vitro by deletion of 3' termination and processing sequences in the human tRNA (i)(met) gene" pp. 1101-1115. see entire article.
13 *See also references of EP0471796A1
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Classificazioni
Classificazione internazionaleA61K39/21, A01K67/027, A61P37/04, C12N15/82, A01H5/00, C12N15/09, C12N15/79, C12N15/85, C12N5/10, C12P21/00, C12N15/67, A61K38/00, A61P31/12, A61K31/70, C12R1/91, C12N15/11, C12N15/113
Classificazione cooperativaC12N15/85, A01K67/027, C12N15/67, C12N15/1132, C12N15/8218, C12N15/79, C12N15/11, C12N2310/13
Classificazione EuropeaC12N15/67, C12N15/85, C12N15/79, C12N15/82B4, C12N15/11, A01K67/027, C12N15/113A1
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