WO1995027049A1 - Hochalkalische protease und deren verwendung - Google Patents

Hochalkalische protease und deren verwendung Download PDF

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Publication number
WO1995027049A1
WO1995027049A1 PCT/EP1995/001141 EP9501141W WO9527049A1 WO 1995027049 A1 WO1995027049 A1 WO 1995027049A1 EP 9501141 W EP9501141 W EP 9501141W WO 9527049 A1 WO9527049 A1 WO 9527049A1
Authority
WO
WIPO (PCT)
Prior art keywords
protease
alkaline protease
subtilisine
compositions
industrial
Prior art date
Application number
PCT/EP1995/001141
Other languages
English (en)
French (fr)
Inventor
Antoine Amory
André Clippe
Gerhard Konieczny-Janda
Hubert Herrmann
Karsten BÖRNER
Original Assignee
Solvay Enzymes Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP95913164A priority Critical patent/EP0753058B1/de
Priority to CA002186764A priority patent/CA2186764C/en
Priority to AT95913164T priority patent/ATE269404T1/de
Priority to AU20731/95A priority patent/AU710223B2/en
Priority to NZ282821A priority patent/NZ282821A/en
Priority to US08/716,293 priority patent/US6190904B1/en
Application filed by Solvay Enzymes Gmbh & Co. Kg filed Critical Solvay Enzymes Gmbh & Co. Kg
Priority to DE59510914T priority patent/DE59510914D1/de
Priority to JP7525398A priority patent/JPH10505741A/ja
Priority to BR9507237A priority patent/BR9507237A/pt
Publication of WO1995027049A1 publication Critical patent/WO1995027049A1/de
Priority to FI963829A priority patent/FI120739B/fi
Priority to MXPA/A/1996/004399A priority patent/MXPA96004399A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39Organic or inorganic per-compounds

Abstract

Die Erfindung betrifft eine neue hochalkalische Protease, deren Verwendung im gewerblichen bzw. industriellen Bereich und im Haushaltsbereich sowie auch Zusammensetzungen für die genannten Anwendungen, die diese Protease enthalten. Bei der erfindungsgemäßen Protease handelt es sich um eine ausgewählte Dreifachmutante, die von bestimmten Vorlauferproteasen aus der Gruppe der Subtilisine, insbesondere vom Typ 'Subtilisin 309', abgeleitet ist.
PCT/EP1995/001141 1994-03-31 1995-03-27 Hochalkalische protease und deren verwendung WO1995027049A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CA002186764A CA2186764C (en) 1994-03-31 1995-03-27 High-alkaline protease and its use
AT95913164T ATE269404T1 (de) 1994-03-31 1995-03-27 Hochalkalische protease und deren verwendung
AU20731/95A AU710223B2 (en) 1994-03-31 1995-03-27 High-alkaline protease and its use
NZ282821A NZ282821A (en) 1994-03-31 1995-03-27 High alkaline protease mutant derived from precursor proteases from the subtilisine group and use in detergents and the manufacture of leather
US08/716,293 US6190904B1 (en) 1994-03-31 1995-03-27 High-alkaline protease and its use arginine-substituted subtilisin composition and use
EP95913164A EP0753058B1 (de) 1994-03-31 1995-03-27 Hochalkalische protease und deren verwendung
DE59510914T DE59510914D1 (de) 1994-03-31 1995-03-27 Hochalkalische protease und deren verwendung
JP7525398A JPH10505741A (ja) 1994-03-31 1995-03-27 高アルカリ性プロテアーゼ及びその使用
BR9507237A BR9507237A (pt) 1994-03-31 1995-03-27 Protease altamente alcalina e sua aplicação
FI963829A FI120739B (fi) 1994-03-31 1996-09-25 Erittäin alkalinen proteaasi ja sen käyttö
MXPA/A/1996/004399A MXPA96004399A (es) 1994-03-31 1996-09-27 Proteasa altamente alcanina y su uso

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4411223.8 1994-03-31
DE4411223A DE4411223A1 (de) 1994-03-31 1994-03-31 Verwendung alkalischer Proteasen in gewerblichen Textilwaschverfahren

Publications (1)

Publication Number Publication Date
WO1995027049A1 true WO1995027049A1 (de) 1995-10-12

Family

ID=6514333

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/001141 WO1995027049A1 (de) 1994-03-31 1995-03-27 Hochalkalische protease und deren verwendung

Country Status (13)

Country Link
US (3) US6190904B1 (de)
EP (2) EP0686692B1 (de)
JP (2) JPH10505741A (de)
CN (1) CN1148406A (de)
AT (2) ATE269404T1 (de)
AU (2) AU710223B2 (de)
BR (2) BR9507237A (de)
CA (2) CA2186764C (de)
DE (3) DE4411223A1 (de)
DK (2) DK0753058T3 (de)
FI (2) FI116681B (de)
NZ (1) NZ282821A (de)
WO (1) WO1995027049A1 (de)

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WO1998020116A1 (en) 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
WO1998020115A1 (en) 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
US5981255A (en) * 1995-11-02 1999-11-09 Novo Nordisk A/S Alkaline protease, process for the production thereof, use thereof, and microorganism producing the same
WO2000071689A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 127 and 128
WO2000071690A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 128 and 129
WO2000071691A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 125 and 126
WO2000071687A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 129 and 130
WO2000071688A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 126 and 127
WO2000071685A1 (en) 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 132 and 133
US6187739B1 (en) 1995-09-21 2001-02-13 Henkel Kommanditgesellschaft Auf Aktien Paste-form washing and cleaning agents
US6190904B1 (en) * 1994-03-31 2001-02-20 Genecor International, Inc. High-alkaline protease and its use arginine-substituted subtilisin composition and use
US6248708B1 (en) 1996-09-05 2001-06-19 Henkel-Ecolab Gmbh & Co. Ohg Paste-form detergent containing a mixture of ethoxylated alcohols
US6380140B1 (en) 1996-04-20 2002-04-30 Henkel Komm.Nditgesellschaft Auf Aktien Enzyme granules containing phosphated starch
US6555355B1 (en) 1997-08-29 2003-04-29 Novozymes, A/S Protease variants and compositions
US6558938B1 (en) 1997-08-29 2003-05-06 Novozymes, A/S Protease variants and compositions
US6605458B1 (en) 1997-11-21 2003-08-12 Novozymes A/S Protease variants and compositions
US6627592B1 (en) 1998-12-15 2003-09-30 Ecolab Gmbh & Co. Ohg Pasty washing agent
DE10241553A1 (de) * 2002-09-05 2004-03-18 Technische Universität Dresden Genetische Varianten in den Genen TIMP-2 und MMP-2 als ätiologische Faktoren verschiedener Erkrankungen
US6727085B2 (en) 1999-12-15 2004-04-27 Fanoe Tina Sejersgaard Subtilase variants having an improved wash performance on egg stains
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6777218B1 (en) 2000-03-14 2004-08-17 Novozymes A/S Subtilase enzymes having an improved wash performance on egg stains
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
WO2005040372A1 (en) 2003-10-23 2005-05-06 Novozymes A/S Protease with improved stability in detergents
EP1803817A1 (de) 1998-12-18 2007-07-04 Novozymes A/S Subtilase Enzyme der I-S1- und I-S2-Untergruppen mit einem zusätzlichen Aminosäurerest in einer aktiven Schleifenregion
WO2008134343A1 (en) 2007-04-30 2008-11-06 Danisco Us Inc., Genencor Division Use of protein hydrolysates to stabilize metalloprotease detergent formulations
US7507569B2 (en) 2003-05-07 2009-03-24 Novozymes A/S Variant subtilisin enzymes (subtilases)
US8785172B2 (en) 2006-04-20 2014-07-22 Novozymes A/S Savinase variants having an improved wash performance on egg stains

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DE69738047T2 (de) * 1996-12-04 2008-05-15 Novozymes North America, Inc. Alkalisches enzymatisches abkochen von baumwolltextilien
DE19703364A1 (de) 1997-01-30 1998-08-06 Henkel Ecolab Gmbh & Co Ohg Pastenförmiges Wasch- und Reinigungsmittel
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DE19904512A1 (de) * 1999-02-04 2000-08-17 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Reinigung von Mehrwegflaschen
AU2001257274A1 (en) * 2000-04-26 2001-11-07 Genencor International, Inc. A method of treating soy proteins and a soy protein product produced by this method
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DE10163883A1 (de) * 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
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JP5867984B2 (ja) 2007-03-12 2016-02-24 ダニスコ・ユーエス・インク 修飾プロテアーゼ
DK2152732T3 (da) 2007-05-10 2012-06-04 Danisco Us Inc Modificeret sekretionssystem til at øge ekspression af polypeptider i bakterier
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US20130260438A1 (en) * 2010-05-06 2013-10-03 Danisco Us Inc. Compositions and methods comprising serine protease variants (as amended)
JP5829844B2 (ja) * 2011-06-24 2015-12-09 太邦株式会社 水溶性エラスチンペプチドの製造方法
KR102126598B1 (ko) * 2012-10-01 2020-06-24 러트거즈,더스테이트유니버시티오브뉴저지 열수 액상 소결(hlps)용 전구물질 및 수송 방법
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Cited By (32)

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Publication number Priority date Publication date Assignee Title
US6190904B1 (en) * 1994-03-31 2001-02-20 Genecor International, Inc. High-alkaline protease and its use arginine-substituted subtilisin composition and use
US6187739B1 (en) 1995-09-21 2001-02-13 Henkel Kommanditgesellschaft Auf Aktien Paste-form washing and cleaning agents
US5981255A (en) * 1995-11-02 1999-11-09 Novo Nordisk A/S Alkaline protease, process for the production thereof, use thereof, and microorganism producing the same
US6380140B1 (en) 1996-04-20 2002-04-30 Henkel Komm.Nditgesellschaft Auf Aktien Enzyme granules containing phosphated starch
US6248708B1 (en) 1996-09-05 2001-06-19 Henkel-Ecolab Gmbh & Co. Ohg Paste-form detergent containing a mixture of ethoxylated alcohols
WO1998020115A1 (en) 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
EP2278001A1 (de) 1996-11-04 2011-01-26 Novozymes A/S Proteasevarianten und Verbindungen
WO1998020116A1 (en) 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
US7288401B2 (en) 1997-08-29 2007-10-30 Novozymes A/S Protease variants and compositions
US6921657B2 (en) 1997-08-29 2005-07-26 Novozymes A/S Protease variants and compositions
US6555355B1 (en) 1997-08-29 2003-04-29 Novozymes, A/S Protease variants and compositions
US6558938B1 (en) 1997-08-29 2003-05-06 Novozymes, A/S Protease variants and compositions
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
US7026153B2 (en) 1997-11-21 2006-04-11 Novozymes A/S Protease variants and compositions
US6605458B1 (en) 1997-11-21 2003-08-12 Novozymes A/S Protease variants and compositions
US6627592B1 (en) 1998-12-15 2003-09-30 Ecolab Gmbh & Co. Ohg Pasty washing agent
EP1803817A1 (de) 1998-12-18 2007-07-04 Novozymes A/S Subtilase Enzyme der I-S1- und I-S2-Untergruppen mit einem zusätzlichen Aminosäurerest in einer aktiven Schleifenregion
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DK0686692T3 (da) 2003-01-06
CA2146063C (en) 2006-03-21
DE59510341D1 (de) 2002-10-02
FI120739B (fi) 2010-02-15
FI963829A (fi) 1996-11-26
BR9501401A (pt) 1996-02-27
CA2186764A1 (en) 1995-10-12
EP0753058B1 (de) 2004-06-16
JPH10505741A (ja) 1998-06-09
US6165960A (en) 2000-12-26
FI951520A0 (fi) 1995-03-30
US6190904B1 (en) 2001-02-20
FI951520A (fi) 1995-10-01
DK0753058T3 (da) 2004-10-11
DE4411223A1 (de) 1995-10-05
MX9604399A (es) 1997-07-31
CA2186764C (en) 2005-08-09
ATE222947T1 (de) 2002-09-15
AU1617595A (en) 1995-10-12
JPH07286194A (ja) 1995-10-31
EP0686692A3 (de) 1997-05-14
CN1148406A (zh) 1997-04-23
AU710223B2 (en) 1999-09-16
EP0686692B1 (de) 2002-08-28
ATE269404T1 (de) 2004-07-15
NZ282821A (en) 1998-09-24
FI963829A0 (fi) 1996-09-25
AU705385B2 (en) 1999-05-20
FI116681B (fi) 2006-01-31
US5880080A (en) 1999-03-09
CA2146063A1 (en) 1995-10-01
EP0753058A1 (de) 1997-01-15
DE59510914D1 (de) 2004-07-22
EP0686692A2 (de) 1995-12-13
AU2073195A (en) 1995-10-23
BR9507237A (pt) 1997-09-16

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