WO2001055173A8 - Nucleic acids, proteins, and antibodies - Google Patents

Nucleic acids, proteins, and antibodies

Info

Publication number
WO2001055173A8
WO2001055173A8 PCT/US2001/001356 US0101356W WO0155173A8 WO 2001055173 A8 WO2001055173 A8 WO 2001055173A8 US 0101356 W US0101356 W US 0101356W WO 0155173 A8 WO0155173 A8 WO 0155173A8
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies
proteins
nucleic acids
nucleic
acids
Prior art date
Application number
PCT/US2001/001356
Other languages
French (fr)
Other versions
WO2001055173A2 (en
Inventor
Craig A Rosen
Steven C Barash
Steven M Ruben
Original Assignee
Human Genome Sciences Inc
Craig A Rosen
Steven C Barash
Steven M Ruben
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, Craig A Rosen, Steven C Barash, Steven M Ruben filed Critical Human Genome Sciences Inc
Publication of WO2001055173A2 publication Critical patent/WO2001055173A2/en
Publication of WO2001055173A8 publication Critical patent/WO2001055173A8/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PCT/US2001/001356 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies WO2001055173A2 (en)

Applications Claiming Priority (235)

Application Number Priority Date Filing Date Title
US17906500P 2000-01-31 2000-01-31
US60/179,065 2000-01-31
US18062800P 2000-02-04 2000-02-04
US60/180,628 2000-02-04
US18466400P 2000-02-24 2000-02-24
US60/184,664 2000-02-24
US18635000P 2000-03-02 2000-03-02
US60/186,350 2000-03-02
US18987400P 2000-03-16 2000-03-16
US60/189,874 2000-03-16
US19007600P 2000-03-17 2000-03-17
US60/190,076 2000-03-17
US19812300P 2000-04-18 2000-04-18
US60/198,123 2000-04-18
US20551500P 2000-05-19 2000-05-19
US60/205,515 2000-05-19
US20946700P 2000-06-07 2000-06-07
US60/209,467 2000-06-07
US21488600P 2000-06-28 2000-06-28
US60/214,886 2000-06-28
US21513500P 2000-06-30 2000-06-30
US60/215,135 2000-06-30
US21664700P 2000-07-07 2000-07-07
US21688000P 2000-07-07 2000-07-07
US60/216,647 2000-07-07
US60/216,880 2000-07-07
US21749600P 2000-07-11 2000-07-11
US21748700P 2000-07-11 2000-07-11
US60/217,487 2000-07-11
US60/217,496 2000-07-11
US21829000P 2000-07-14 2000-07-14
US60/218,290 2000-07-14
US22096300P 2000-07-26 2000-07-26
US22096400P 2000-07-26 2000-07-26
US60/220,964 2000-07-26
US60/220,963 2000-07-26
US22544700P 2000-08-14 2000-08-14
US22451900P 2000-08-14 2000-08-14
US22521400P 2000-08-14 2000-08-14
US22575900P 2000-08-14 2000-08-14
US22526800P 2000-08-14 2000-08-14
US22451800P 2000-08-14 2000-08-14
US22521300P 2000-08-14 2000-08-14
US22526700P 2000-08-14 2000-08-14
US22575800P 2000-08-14 2000-08-14
US22575700P 2000-08-14 2000-08-14
US22526600P 2000-08-14 2000-08-14
US22527000P 2000-08-14 2000-08-14
US60/224,518 2000-08-14
US60/225,757 2000-08-14
US60/225,267 2000-08-14
US60/225,268 2000-08-14
US60/225,758 2000-08-14
US60/225,214 2000-08-14
US60/225,213 2000-08-14
US60/225,447 2000-08-14
US60/224,519 2000-08-14
US60/225,266 2000-08-14
US60/225,270 2000-08-14
US60/225,759 2000-08-14
US22627900P 2000-08-18 2000-08-18
US60/226,279 2000-08-18
US22718200P 2000-08-22 2000-08-22
US22686800P 2000-08-22 2000-08-22
US22668100P 2000-08-22 2000-08-22
US60/226,868 2000-08-22
US60/227,182 2000-08-22
US60/226,681 2000-08-22
US22700900P 2000-08-23 2000-08-23
US60/227,009 2000-08-23
US22892400P 2000-08-30 2000-08-30
US60/228,924 2000-08-30
US22934500P 2000-09-01 2000-09-01
US22934400P 2000-09-01 2000-09-01
US22934300P 2000-09-01 2000-09-01
US22928700P 2000-09-01 2000-09-01
US60/229,344 2000-09-01
US60/229,345 2000-09-01
US60/229,343 2000-09-01
US60/229,287 2000-09-01
US22950900P 2000-09-05 2000-09-05
US22951300P 2000-09-05 2000-09-05
US60/229,509 2000-09-05
US60/229,513 2000-09-05
US23043700P 2000-09-06 2000-09-06
US23043800P 2000-09-06 2000-09-06
US60/230,437 2000-09-06
US60/230,438 2000-09-06
US23124400P 2000-09-08 2000-09-08
US23208000P 2000-09-08 2000-09-08
US23141400P 2000-09-08 2000-09-08
US23141300P 2000-09-08 2000-09-08
US23124200P 2000-09-08 2000-09-08
US23124300P 2000-09-08 2000-09-08
US23208100P 2000-09-08 2000-09-08
US60/232,080 2000-09-08
US60/232,081 2000-09-08
US60/231,413 2000-09-08
US60/231,242 2000-09-08
US60/231,244 2000-09-08
US60/231,414 2000-09-08
US60/231,243 2000-09-08
US23196800P 2000-09-12 2000-09-12
US60/231,968 2000-09-12
US23306300P 2000-09-14 2000-09-14
US23306400P 2000-09-14 2000-09-14
US23239800P 2000-09-14 2000-09-14
US23306500P 2000-09-14 2000-09-14
US23240000P 2000-09-14 2000-09-14
US23239900P 2000-09-14 2000-09-14
US23240100P 2000-09-14 2000-09-14
US23239700P 2000-09-14 2000-09-14
US60/232,398 2000-09-14
US60/232,400 2000-09-14
US60/232,401 2000-09-14
US60/233,064 2000-09-14
US60/232,399 2000-09-14
US60/233,065 2000-09-14
US60/233,063 2000-09-14
US60/232,397 2000-09-14
US23427400P 2000-09-21 2000-09-21
US23422300P 2000-09-21 2000-09-21
US60/234,274 2000-09-21
US60/234,223 2000-09-21
US23499800P 2000-09-25 2000-09-25
US23499700P 2000-09-25 2000-09-25
US60/234,997 2000-09-25
US60/234,998 2000-09-25
US23548400P 2000-09-26 2000-09-26
US60/235,484 2000-09-26
US23583600P 2000-09-27 2000-09-27
US23583400P 2000-09-27 2000-09-27
US60/235,836 2000-09-27
US60/235,834 2000-09-27
US23636700P 2000-09-29 2000-09-29
US23636900P 2000-09-29 2000-09-29
US23637000P 2000-09-29 2000-09-29
US23636800P 2000-09-29 2000-09-29
US23632700P 2000-09-29 2000-09-29
US60/236,327 2000-09-29
US60/236,367 2000-09-29
US60/236,370 2000-09-29
US60/236,368 2000-09-29
US60/236,369 2000-09-29
US23703700P 2000-10-02 2000-10-02
US23704000P 2000-10-02 2000-10-02
US23680200P 2000-10-02 2000-10-02
US23703800P 2000-10-02 2000-10-02
US23703900P 2000-10-02 2000-10-02
US60/236,802 2000-10-02
US60/237,039 2000-10-02
US60/237,037 2000-10-02
US60/237,040 2000-10-02
US60/237,038 2000-10-02
US23993500P 2000-10-13 2000-10-13
US23993700P 2000-10-13 2000-10-13
US60/239,937 2000-10-13
US60/239,935 2000-10-13
US24178700P 2000-10-20 2000-10-20
US24180800P 2000-10-20 2000-10-20
US24182600P 2000-10-20 2000-10-20
US24122100P 2000-10-20 2000-10-20
US24178600P 2000-10-20 2000-10-20
US24178500P 2000-10-20 2000-10-20
US24096000P 2000-10-20 2000-10-20
US24180900P 2000-10-20 2000-10-20
US60/241,826 2000-10-20
US60/241,221 2000-10-20
US60/240,960 2000-10-20
US60/241,808 2000-10-20
US60/241,809 2000-10-20
US60/241,785 2000-10-20
US60/241,786 2000-10-20
US60/241,787 2000-10-20
US24461700P 2000-11-01 2000-11-01
US60/244,617 2000-11-01
US24661000P 2000-11-08 2000-11-08
US24652700P 2000-11-08 2000-11-08
US24653200P 2000-11-08 2000-11-08
US24661100P 2000-11-08 2000-11-08
US24647400P 2000-11-08 2000-11-08
US24652500P 2000-11-08 2000-11-08
US24647700P 2000-11-08 2000-11-08
US24647600P 2000-11-08 2000-11-08
US24652800P 2000-11-08 2000-11-08
US24652600P 2000-11-08 2000-11-08
US24647500P 2000-11-08 2000-11-08
US60/246,475 2000-11-08
US60/246,613 2000-11-08
US60/246,610 2000-11-08
US60/246,528 2000-11-08
US60/246,476 2000-11-08
US60/246,524 2000-11-08
US60/246,525 2000-11-08
US60/246,474 2000-11-08
US60/246,523 2000-11-08
US60/246,477 2000-11-08
US60/246,527 2000-11-08
US60/246,611 2000-11-08
US60/246,609 2000-11-08
US60/246,478 2000-11-08
US60/246,526 2000-11-08
US60/246,532 2000-11-08
US60/249,245 2000-11-17
US60/249,300 2000-11-17
US60/249,264 2000-11-17
US60/249,212 2000-11-17
US60/249,209 2000-11-17
US60/249,210 2000-11-17
US60/249,244 2000-11-17
US60/249,297 2000-11-17
US60/249,215 2000-11-17
US60/249,299 2000-11-17
US60/249,213 2000-11-17
US60/249,217 2000-11-17
US60/249,207 2000-11-17
US60/249,265 2000-11-17
US60/249,218 2000-11-17
US60/249,211 2000-11-17
US60/249,208 2000-11-17
US60/249,216 2000-11-17
US60/249,214 2000-11-17
US60/250,391 2000-12-01
US60/250,160 2000-12-01
US60/256,719 2000-12-05
US60/251,988 2000-12-05
US60/251,030 2000-12-05
US60/251,479 2000-12-06
US60/251,868 2000-12-08
US60/251,856 2000-12-08
US60/251,869 2000-12-08
US60/251,989 2000-12-08
US60/251,990 2000-12-08
US60/254,097 2000-12-11
US60/259,678 2001-01-05

Publications (2)

Publication Number Publication Date
WO2001055173A2 WO2001055173A2 (en) 2001-08-02
WO2001055173A8 true WO2001055173A8 (en) 2001-11-29

Family

ID=27587117

Family Applications (48)

Application Number Title Priority Date Filing Date
PCT/US2001/001358 WO2001055163A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001348 WO2001055368A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001333 WO2001055448A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001344 WO2001055324A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001315 WO2001055311A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001321 WO2001055312A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001322 WO2001055343A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001332 WO2001055318A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001345 WO2001055325A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001326 WO2001055315A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001349 WO2001054474A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001317 WO2001055201A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001306 WO2001055307A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001342 WO2001059064A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001351 WO2001055355A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001301 WO2001055303A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001324 WO2001055314A2 (en) 2000-01-31 2001-01-17 Digestive system related nucleic acids, proteins and antibodies
PCT/US2001/001316 WO2001054473A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001302 WO2001055304A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001353 WO2001055206A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001336 WO2001055204A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001356 WO2001055173A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001330 WO2001055447A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001350 WO2001055350A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001309 WO2001055308A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001355 WO2001055207A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001240 WO2001055302A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001357 WO2001055208A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001312 WO2001054733A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins and antibodies
PCT/US2001/001339 WO2001055320A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001314 WO2001055310A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001308 WO2001055364A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001340 WO2001055321A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001311 WO2001055309A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001327 WO2001055203A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001343 WO2001055323A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001239 WO2001055301A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001310 WO2001055387A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001354 WO2001057182A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001338 WO2001055367A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001359 WO2001055328A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001313 WO2001055200A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001335 WO2001055319A2 (en) 2000-01-31 2001-01-17 Endocrine related nucleic acids, proteins and antibodies
PCT/US2001/001325 WO2001055202A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001337 WO2001055205A1 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
PCT/US2001/001352 WO2001055327A2 (en) 2000-01-31 2001-01-17 Nucleic acids, proteins, and antibodies
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