WO2002092573A3 - Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases - Google Patents
Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases Download PDFInfo
- Publication number
- WO2002092573A3 WO2002092573A3 PCT/US2002/015606 US0215606W WO02092573A3 WO 2002092573 A3 WO2002092573 A3 WO 2002092573A3 US 0215606 W US0215606 W US 0215606W WO 02092573 A3 WO02092573 A3 WO 02092573A3
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- WIPO (PCT)
- Prior art keywords
- inhibitors
- src
- protein kinases
- heterocyclic substituted
- substituted pyrazoles
- Prior art date
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- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002308748A AU2002308748A1 (en) | 2001-05-16 | 2002-05-16 | Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases |
EP02769762A EP1404669A2 (en) | 2001-05-16 | 2002-05-16 | Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases |
JP2002589459A JP4316893B2 (en) | 2001-05-16 | 2002-05-16 | Inhibitors of Src and other protein kinases |
CA2446864A CA2446864C (en) | 2001-05-16 | 2002-05-16 | Inhibitors of src and other protein kinases |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29134001P | 2001-05-16 | 2001-05-16 | |
US60/291,340 | 2001-05-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002092573A2 WO2002092573A2 (en) | 2002-11-21 |
WO2002092573A3 true WO2002092573A3 (en) | 2004-01-22 |
Family
ID=23119908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/015606 WO2002092573A2 (en) | 2001-05-16 | 2002-05-16 | Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases |
Country Status (6)
Country | Link |
---|---|
US (1) | US6884804B2 (en) |
EP (1) | EP1404669A2 (en) |
JP (1) | JP4316893B2 (en) |
AU (1) | AU2002308748A1 (en) |
CA (1) | CA2446864C (en) |
WO (1) | WO2002092573A2 (en) |
Cited By (17)
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US8691807B2 (en) | 2011-06-20 | 2014-04-08 | Incyte Corporation | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors |
US8933085B2 (en) | 2010-11-19 | 2015-01-13 | Incyte Corporation | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
US8933086B2 (en) | 2005-12-13 | 2015-01-13 | Incyte Corporation | Heteroaryl substituted pyrrolo[2,3-B]pyridines and pyrrolo[2,3-B]pyrimidines as Janus kinase inhibitors |
US8987443B2 (en) | 2013-03-06 | 2015-03-24 | Incyte Corporation | Processes and intermediates for making a JAK inhibitor |
US9034884B2 (en) | 2010-11-19 | 2015-05-19 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors |
US9193733B2 (en) | 2012-05-18 | 2015-11-24 | Incyte Holdings Corporation | Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
US9216984B2 (en) | 2009-05-22 | 2015-12-22 | Incyte Corporation | 3-[4-(7H-pyrrolo[2,3-D]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane—or heptane-nitrile as JAK inhibitors |
US9249145B2 (en) | 2009-09-01 | 2016-02-02 | Incyte Holdings Corporation | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
US9295737B2 (en) | 2002-03-01 | 2016-03-29 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
US9334274B2 (en) | 2009-05-22 | 2016-05-10 | Incyte Holdings Corporation | N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
US9359358B2 (en) | 2011-08-18 | 2016-06-07 | Incyte Holdings Corporation | Cyclohexyl azetidine derivatives as JAK inhibitors |
US9408926B2 (en) | 2002-03-01 | 2016-08-09 | Bracco Suisse S.A. | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9446155B2 (en) | 2002-03-01 | 2016-09-20 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9464088B2 (en) | 2010-03-10 | 2016-10-11 | Incyte Holdings Corporation | Piperidin-4-yl azetidine derivatives as JAK1 inhibitors |
US9487521B2 (en) | 2011-09-07 | 2016-11-08 | Incyte Holdings Corporation | Processes and intermediates for making a JAK inhibitor |
US9498467B2 (en) | 2014-05-30 | 2016-11-22 | Incyte Corporation | Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1 |
US11851426B2 (en) | 2019-10-11 | 2023-12-26 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
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Also Published As
Publication number | Publication date |
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AU2002308748A1 (en) | 2002-11-25 |
CA2446864A1 (en) | 2002-11-21 |
CA2446864C (en) | 2011-02-15 |
US6884804B2 (en) | 2005-04-26 |
EP1404669A2 (en) | 2004-04-07 |
US20030144309A1 (en) | 2003-07-31 |
JP2004534754A (en) | 2004-11-18 |
WO2002092573A2 (en) | 2002-11-21 |
JP4316893B2 (en) | 2009-08-19 |
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