WO2002095401A3 - Screening test and procedure using skin patches - Google Patents

Screening test and procedure using skin patches Download PDF

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Publication number
WO2002095401A3
WO2002095401A3 PCT/US2001/044319 US0144319W WO02095401A3 WO 2002095401 A3 WO2002095401 A3 WO 2002095401A3 US 0144319 W US0144319 W US 0144319W WO 02095401 A3 WO02095401 A3 WO 02095401A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
sweat
existence
indicate
markers
Prior art date
Application number
PCT/US2001/044319
Other languages
French (fr)
Other versions
WO2002095401A2 (en
Inventor
Stuart Berlin
Original Assignee
Stuart Berlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stuart Berlin filed Critical Stuart Berlin
Publication of WO2002095401A2 publication Critical patent/WO2002095401A2/en
Publication of WO2002095401A3 publication Critical patent/WO2002095401A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate

Abstract

Marker compounds indicative of variations in physiological conditions, genetic defects or disease states have been found to be present in spocrine sweat and, in many conditions, these markers are present in apocrine sweat in elevated levels when compared to blood. These markers are collected and/or detected in apocrine sweat and used as an indicator that a disease state or particular physiological condition exists. A skin patch, wipe or electronic detector for vapors released from spocrine sweat are used to indicate the existence of a disease state or changing physiological condition. The patch or wipe can include in monoclonal antibodies or other chemical compounds that can indicate the presence of specific markers. This may include indicators that render visible, the existence of a reaction between the monoclonal antibody or chemical compound and the marker compound to indicate the existence of the condition being tested for. Various different disease states can be detected including, but not limited to heart disease, cancer, autoimmune disease, viral or bacterial disease, renal disease, drug intoxication and other systemic illnesses. Fertility for conception and histocompatibility for organ transplantation of individuals should also be detectable.
PCT/US2001/044319 2000-11-29 2001-11-27 Screening test and procedure using skin patches WO2002095401A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25020600P 2000-11-29 2000-11-29
US60/250,206 2000-11-29
US09/994,535 US6585646B2 (en) 2000-11-29 2001-11-26 Screening test and procedure using skin patches

Publications (2)

Publication Number Publication Date
WO2002095401A2 WO2002095401A2 (en) 2002-11-28
WO2002095401A3 true WO2002095401A3 (en) 2003-08-28

Family

ID=26940684

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/044319 WO2002095401A2 (en) 2000-11-29 2001-11-27 Screening test and procedure using skin patches

Country Status (2)

Country Link
US (2) US6585646B2 (en)
WO (1) WO2002095401A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2537796C (en) 2003-09-03 2013-12-03 Life Patch International, Inc. Personal diagnostic devices and related methods
US20050283380A1 (en) * 2004-06-18 2005-12-22 Garduno Ramon S Delivery service for a health management system
WO2008006153A1 (en) * 2006-07-11 2008-01-17 Paul Nigel Brockwell Medical indicator method and device
US20080103823A1 (en) * 2006-11-01 2008-05-01 Papa Angelo A Method for coordinating professional services
CA2694120A1 (en) * 2007-06-22 2008-12-31 Expression Pathology Method of discovering and analyzing secreted biomarkers of disease from solid tissue
US20120046964A1 (en) * 2007-10-30 2012-02-23 Papa Angelo A Method of coordinating professional services
EP2454587A4 (en) * 2009-07-13 2012-12-12 Freelance Corp Devices, methods, and kits for determining analyte concentrations
CN102687323B (en) 2009-12-22 2015-09-30 3M创新有限公司 Subpad chip is adopted to save the good fuel cell subassemblies of film
US9456780B2 (en) * 2013-02-07 2016-10-04 Hill-Rom Services, Inc. Dynamic therapy delivery system
WO2015066459A1 (en) * 2013-10-31 2015-05-07 Medtech Bioscience, Llc Analyte detection device and methods of using same
WO2016207070A1 (en) 2015-06-24 2016-12-29 Koninklijke Philips N.V. Sweat monitoring apparatus and monitoring method
JP6555973B2 (en) * 2015-08-05 2019-08-07 株式会社マンダム How to check sweat gland morphology
GB2535614B (en) 2015-12-22 2017-06-14 Tfm Invent Ltd A skin patch
WO2018013579A1 (en) * 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
CZ307724B6 (en) * 2017-08-29 2019-03-20 Fakultní nemocnice Hradec Králové A method of diagnosing breast cancer from a sample of apocrine sweat
EP3700408A1 (en) * 2017-10-25 2020-09-02 Skindicator AB A device and a method for detection of changes in tissue
EP3622880A1 (en) * 2018-09-11 2020-03-18 Koninklijke Philips N.V. Method and apparatus for differential sweat measurement
NL2025094B1 (en) 2020-03-10 2021-10-19 Koninklijke Philips Nv Method of positioning a sweat sensor device
US11123011B1 (en) 2020-03-23 2021-09-21 Nix, Inc. Wearable systems, devices, and methods for measurement and analysis of body fluids

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868106A (en) * 1985-10-17 1989-09-19 Konishiroku Photo Industry Co., Ltd. Analytical element and method for determining a component in a test sample
EP0737442A1 (en) * 1992-12-07 1996-10-16 Hisamitsu Pharmaceutical Co., Inc. Plaster for testing and method of testing
EP0811847A2 (en) * 1996-06-05 1997-12-10 Roche Diagnostics GmbH Method for detection of analytes on a surface
US5891649A (en) * 1996-08-08 1999-04-06 California Institute Of Technology Real-time biochemical assay telemetering system
DE29902593U1 (en) * 1999-02-13 1999-07-15 Genzyme Virotech Gmbh Gas analyzer for medical diagnostics
US5944662A (en) * 1988-09-08 1999-08-31 Sudormed, Inc. Method and apparatus of determination of chemical species in perspiration
US6042543A (en) * 1997-03-11 2000-03-28 Regents Of The University Of Minnesota Test device and method for quantitative measurement of an analyte in a liquid

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3552929A (en) 1968-01-23 1971-01-05 Minnesota Mining & Mfg Diagnosis means
US4329999A (en) 1980-03-03 1982-05-18 Michael Phillips Patient attached patch and method of making
US4444193A (en) * 1982-01-11 1984-04-24 Medtronic, Inc. Fluid absorbent quantitative test device
US4732153A (en) * 1984-07-18 1988-03-22 Michael Phillips Transdermal dosimeter
US4931403A (en) * 1985-01-25 1990-06-05 Monell Chemical Senses Center Axillary androstenol and dehydroepiandrosterone as fertile period onset indicators
US4706676A (en) 1985-02-11 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection device
US5459080A (en) 1988-01-29 1995-10-17 Abbott Laboratories Ion-capture assays using a specific binding member conjugated to carboxymethylamylose
US5203327A (en) * 1988-09-08 1993-04-20 Sudor Partners Method and apparatus for determination of chemical species in body fluid
US5445147A (en) 1988-09-08 1995-08-29 Sudor Partners Method and apparatus for determination of chemical species in body fluid
US5465713A (en) 1988-09-08 1995-11-14 Sudor Partners Energy-assisted transdermal collection patch for accelerated analyte collection and method of use
US5076273A (en) 1988-09-08 1991-12-31 Sudor Partners Method and apparatus for determination of chemical species in body fluid
US4957108A (en) 1988-09-08 1990-09-18 Sudor Partners Method and apparatus for determination of chemical species in body fluid
US6040194A (en) 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5470970A (en) 1991-02-28 1995-11-28 Dana-Farber Cancer Institute, Inc. Maspin, a serpin with tumor suppresing activity
US5443080A (en) * 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
WO1996032142A1 (en) 1995-04-12 1996-10-17 Hopp Robert B Skin patch for use in contact immunotherapy
US5525521A (en) * 1995-06-15 1996-06-11 Borrego Analytical, Inc. Cystic fibrosis tester
US6143529A (en) * 1996-08-14 2000-11-07 Exact Laboratories, Inc. Methods for improving sensitivity and specificity of screening assays
US5798266A (en) 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US5911976A (en) * 1996-10-24 1999-06-15 The Procter & Gamble Company Compositions for reducing body odor
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US5895765A (en) 1997-06-30 1999-04-20 Bayer Corporation Method for the detection of an analyte by immunochromatography
US6479015B1 (en) * 1998-03-03 2002-11-12 Pepex Biomedical, Llc Apparatus for monitoring a level of a chemical species in a body fluid
US6762032B1 (en) * 1999-08-23 2004-07-13 Biocrystal, Ltd. Compositions, assay kits, and methods for use related to a disease condition comprising multiple sclerosis and/or a pro-MS immune response
US6680203B2 (en) * 2000-07-10 2004-01-20 Esperion Therapeutics, Inc. Fourier transform mass spectrometry of complex biological samples
US6443892B1 (en) * 2000-09-28 2002-09-03 The United States Of America As Represented By The Secretary Of The Navy Sweat collecting device and methods for use and detection of tampering

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868106A (en) * 1985-10-17 1989-09-19 Konishiroku Photo Industry Co., Ltd. Analytical element and method for determining a component in a test sample
US5944662A (en) * 1988-09-08 1999-08-31 Sudormed, Inc. Method and apparatus of determination of chemical species in perspiration
EP0737442A1 (en) * 1992-12-07 1996-10-16 Hisamitsu Pharmaceutical Co., Inc. Plaster for testing and method of testing
EP0811847A2 (en) * 1996-06-05 1997-12-10 Roche Diagnostics GmbH Method for detection of analytes on a surface
US5891649A (en) * 1996-08-08 1999-04-06 California Institute Of Technology Real-time biochemical assay telemetering system
US6042543A (en) * 1997-03-11 2000-03-28 Regents Of The University Of Minnesota Test device and method for quantitative measurement of an analyte in a liquid
DE29902593U1 (en) * 1999-02-13 1999-07-15 Genzyme Virotech Gmbh Gas analyzer for medical diagnostics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BALABANOVA S ET AL: "[Detection of drugs in sweat]", BEITRAGE ZUR GERICHTLICHEN MEDIZIN. AUSTRIA 1990, vol. 48, 1990, pages 45 - 49, XP009009462, ISSN: 0067-5016 *

Also Published As

Publication number Publication date
US20020115921A1 (en) 2002-08-22
US20030199743A1 (en) 2003-10-23
WO2002095401A2 (en) 2002-11-28
US6585646B2 (en) 2003-07-01

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