WO2002096267A3 - Noninvasive intraductal fluid diagnostic screen - Google Patents

Noninvasive intraductal fluid diagnostic screen Download PDF

Info

Publication number
WO2002096267A3
WO2002096267A3 PCT/US2002/016900 US0216900W WO02096267A3 WO 2002096267 A3 WO2002096267 A3 WO 2002096267A3 US 0216900 W US0216900 W US 0216900W WO 02096267 A3 WO02096267 A3 WO 02096267A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast
compression
intraductal fluid
intraductal
disease markers
Prior art date
Application number
PCT/US2002/016900
Other languages
French (fr)
Other versions
WO2002096267A2 (en
Inventor
Kevin Morton
Original Assignee
Neomatrix Llc
Kevin Morton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/870,402 external-priority patent/US6866994B2/en
Application filed by Neomatrix Llc, Kevin Morton filed Critical Neomatrix Llc
Priority to CA002448011A priority Critical patent/CA2448011C/en
Priority to EP02774121A priority patent/EP1402056A4/en
Priority to AU2002308784A priority patent/AU2002308784B2/en
Priority to JP2002592787A priority patent/JP2004532082A/en
Publication of WO2002096267A2 publication Critical patent/WO2002096267A2/en
Publication of WO2002096267A3 publication Critical patent/WO2002096267A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6834—Means for maintaining contact with the body using vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0041—Detection of breast cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/06—Milking pumps
    • A61M1/062—Pump accessories
    • A61M1/064—Suction cups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/06—Milking pumps
    • A61M1/062—Pump accessories
    • A61M1/064—Suction cups
    • A61M1/066—Inserts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance

Abstract

Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating, and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. Sample size and intraductal mobility of breast disease markers may be enhanced by retrograde introduction of a carrier. A portable, self-contained intraductal fluid aspiration device (20) includes a housing (22), one or more controls and/or indicators (25), and a patient or breast interface (24) having a tissue contacting surface (32) for receiving a breast and a second concavity (38) for receiving a nipple. Preferably, the breast interface (24) is provided with a dynamic compression zone (42), having one or more compression elements (45) for compression in the mid breast region to facilitate intraductal fluid aspiration.
PCT/US2002/016900 2001-05-30 2002-05-29 Noninvasive intraductal fluid diagnostic screen WO2002096267A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002448011A CA2448011C (en) 2001-05-30 2002-05-29 Noninvasive intraductal fluid diagnostic screen
EP02774121A EP1402056A4 (en) 2001-05-30 2002-05-29 Noninvasive intraductal fluid diagnostic screen
AU2002308784A AU2002308784B2 (en) 2001-05-30 2002-05-29 Noninvasive intraductal fluid diagnostic screen
JP2002592787A JP2004532082A (en) 2001-05-30 2002-05-29 Non-invasive intraluminal fluid diagnostic screen

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US09/870,402 US6866994B2 (en) 2001-05-30 2001-05-30 Noninvasive intraductal fluid diagnostic screen
US09/870,402 2001-05-30
US10/072,537 US6981950B2 (en) 2001-05-30 2002-02-08 Noninvasive intraductal fluid sampling device
US10/072,543 US7575557B2 (en) 2001-05-30 2002-02-08 Disposable fluid loop for intraductal fluid aspiration system
US10/072,539 2002-02-08
US10/072,543 2002-02-08
US10/072,539 US6712785B2 (en) 2001-05-30 2002-02-08 Method of noninvasively obtaining intraductal fluid
US10/072,546 US6676610B2 (en) 2001-05-30 2002-02-08 Disposable patient interface for intraductal fluid aspiration system
US10/072,537 2002-02-08
US10/072,546 2002-02-08

Publications (2)

Publication Number Publication Date
WO2002096267A2 WO2002096267A2 (en) 2002-12-05
WO2002096267A3 true WO2002096267A3 (en) 2003-02-20

Family

ID=27535932

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/016900 WO2002096267A2 (en) 2001-05-30 2002-05-29 Noninvasive intraductal fluid diagnostic screen

Country Status (5)

Country Link
EP (1) EP1402056A4 (en)
JP (1) JP2004532082A (en)
AU (1) AU2002308784B2 (en)
CA (1) CA2448011C (en)
WO (1) WO2002096267A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102711595A (en) * 2010-01-14 2012-10-03 加利福尼亚大学董事会 Devices, systems and methods to detect and reduce or prevent entry of inflammatory mediators into milk ducts

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798266A (en) * 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US6221622B1 (en) * 1998-04-28 2001-04-24 The Regents Of The University Of California Method and kit for obtaining fluids and cellular material from breast ducts
US6328709B1 (en) * 1998-11-13 2001-12-11 Pro Duct Health, Inc. Devices and methods to identify ductal orifices during nipple aspiration
US6391026B1 (en) * 1998-09-18 2002-05-21 Pro Duct Health, Inc. Methods and systems for treating breast tissue

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL73732C (en) * 1948-10-08
US5843029A (en) * 1995-10-16 1998-12-01 Gerber/Baby Care Manual breast pump
NO307079B1 (en) * 1996-11-12 2000-02-07 Tone Nordvik Breast device
EP1495301A4 (en) * 1998-12-28 2005-04-13 Cytyc Corp Devices, methods and systems for collecting material from a breast duct
WO2000043550A2 (en) 1999-01-21 2000-07-27 Wayne State University Method and apparatus for measuring factors in mammary fluids
US6610484B1 (en) * 1999-01-26 2003-08-26 Cytyc Health Corporation Identifying material from a breast duct
US6638727B1 (en) * 1999-01-26 2003-10-28 Cytyc Health Corporation Methods for identifying treating or monitoring asymptomatic patients for risk reduction or therapeutic treatment of breast cancer
WO2000047247A1 (en) * 1999-02-12 2000-08-17 Medo Elena T Bifurcated method for preventing breast ductal cancer
EP1165160B1 (en) * 1999-03-01 2007-08-08 Cytyc Corporation Apparatus, methods and kits for simultaneous delivery of a substance to multiple breast milk ducts
US6607495B1 (en) * 1999-06-18 2003-08-19 University Of Virginia Patent Foundation Apparatus for fluid transport and related method thereof
WO2002038032A2 (en) * 2000-11-13 2002-05-16 Atossa Healthcare, Inc. Methods and devices for collecting and processing mammary fluid

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798266A (en) * 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US6221622B1 (en) * 1998-04-28 2001-04-24 The Regents Of The University Of California Method and kit for obtaining fluids and cellular material from breast ducts
US20010001059A1 (en) * 1998-04-28 2001-05-10 The Regents Of The University Of California. Method and kit for obtaining fluids and cellular material from breast ducts
US6391026B1 (en) * 1998-09-18 2002-05-21 Pro Duct Health, Inc. Methods and systems for treating breast tissue
US6328709B1 (en) * 1998-11-13 2001-12-11 Pro Duct Health, Inc. Devices and methods to identify ductal orifices during nipple aspiration

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1402056A4 *

Also Published As

Publication number Publication date
WO2002096267A2 (en) 2002-12-05
JP2004532082A (en) 2004-10-21
EP1402056A2 (en) 2004-03-31
AU2002308784B2 (en) 2008-04-17
EP1402056A4 (en) 2009-04-08
CA2448011C (en) 2010-01-19
CA2448011A1 (en) 2002-12-05

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