WO2003075843A3 - Multiple and multivalent dna vaccines in ovo - Google Patents

Multiple and multivalent dna vaccines in ovo Download PDF

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Publication number
WO2003075843A3
WO2003075843A3 PCT/US2003/006811 US0306811W WO03075843A3 WO 2003075843 A3 WO2003075843 A3 WO 2003075843A3 US 0306811 W US0306811 W US 0306811W WO 03075843 A3 WO03075843 A3 WO 03075843A3
Authority
WO
WIPO (PCT)
Prior art keywords
dna
multivalent
dna vaccine
fowl
avian viral
Prior art date
Application number
PCT/US2003/006811
Other languages
French (fr)
Other versions
WO2003075843A2 (en
Inventor
Tsun-Yung Kuo
Original Assignee
Schweitzer Chemical Corp Usa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweitzer Chemical Corp Usa filed Critical Schweitzer Chemical Corp Usa
Priority to JP2003574119A priority Critical patent/JP4999258B2/en
Priority to BRPI0308365A priority patent/BRPI0308365B1/en
Priority to EP03744203.5A priority patent/EP1490105B1/en
Priority to CN038080001A priority patent/CN1646157B/en
Priority to AU2003216531A priority patent/AU2003216531B2/en
Priority to MXPA04008692A priority patent/MXPA04008692A/en
Priority to CA2478081A priority patent/CA2478081C/en
Publication of WO2003075843A2 publication Critical patent/WO2003075843A2/en
Publication of WO2003075843A3 publication Critical patent/WO2003075843A3/en
Priority to IL163859A priority patent/IL163859A/en
Priority to IL198505A priority patent/IL198505A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

The present invention provides a multiple DNA vaccine and/or a multivalent DNA vaccine for use in acquiring embryonic immunity in fowl eggs. The multiple DNA vaccine contains two or more DNA constructs, each containing a DNA molecule encoding an avian viral protein or a fragment thereof capable of inducing a protective immune response against the avian viral disease in fowl. The multivalent DNA vaccine contains one DNA construct which contains two or more DNA molecules, each representing an avian viral gene or a fragment thereof. The multivalent DNA vaccine is capable of expressing two or more viral antigens and inducing protective immune responses against the avian viral diseases in fowl.
PCT/US2003/006811 2002-03-08 2003-03-06 Multiple and multivalent dna vaccines in ovo WO2003075843A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP2003574119A JP4999258B2 (en) 2002-03-08 2003-03-06 In vivo (INVIVO) multiple and multivalent DNA vaccines
BRPI0308365A BRPI0308365B1 (en) 2002-03-08 2003-03-06 multiple injection dna vaccine in ovo
EP03744203.5A EP1490105B1 (en) 2002-03-08 2003-03-06 Multiple and multivalent dna vaccines in ovo
CN038080001A CN1646157B (en) 2002-03-08 2003-03-06 Multiple and multivalent DNA vaccines in ovo
AU2003216531A AU2003216531B2 (en) 2002-03-08 2003-03-06 Multiple and multivalent DNA vaccines in ovo
MXPA04008692A MXPA04008692A (en) 2002-03-08 2003-03-06 Multiple and multivalent dna vaccines in ovo.
CA2478081A CA2478081C (en) 2002-03-08 2003-03-06 Multiple and multivalent dna vaccines in ovo
IL163859A IL163859A (en) 2002-03-08 2004-09-01 Multiple and multivalent dna vaccines in ovo
IL198505A IL198505A (en) 2002-03-08 2009-05-03 Multivalent dna vaccine for in ovo injection

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36254702P 2002-03-08 2002-03-08
US60/362,547 2002-03-08
US10/377,718 US7029681B2 (en) 2002-03-08 2003-03-04 Multiple and multivalent DNA vaccines in ovo
US10/377,718 2003-03-04

Publications (2)

Publication Number Publication Date
WO2003075843A2 WO2003075843A2 (en) 2003-09-18
WO2003075843A3 true WO2003075843A3 (en) 2004-07-22

Family

ID=27807969

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/006811 WO2003075843A2 (en) 2002-03-08 2003-03-06 Multiple and multivalent dna vaccines in ovo

Country Status (10)

Country Link
US (1) US7029681B2 (en)
EP (1) EP1490105B1 (en)
JP (2) JP4999258B2 (en)
CN (2) CN101703770A (en)
AU (1) AU2003216531B2 (en)
BR (1) BRPI0308365B1 (en)
CA (1) CA2478081C (en)
IL (2) IL163859A0 (en)
MX (1) MXPA04008692A (en)
WO (1) WO2003075843A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037506B2 (en) * 2002-03-08 2006-05-02 Schweltzer Chemical Corporation Ltd. Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry
WO2009076668A2 (en) * 2007-12-13 2009-06-18 Alpharma, Inc. Bacteriophage preparations and method of use thereof
US9096869B2 (en) 2011-10-21 2015-08-04 Intervet, Inc. Recombinant nonpathogenic MDV vector providing multivalent immunity
WO2013057236A1 (en) 2011-10-21 2013-04-25 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and newcastle disease virus antigens
EP2644702A1 (en) * 2012-03-30 2013-10-02 Ceva Sante Animale Multivalent recombinant avian herpes virus and vaccine for immunizing avian species
CN102895660B (en) * 2012-10-25 2014-04-23 中国兽医药品监察所 Bivalent inactivated vaccine for duck virus hepatitis
US9950059B2 (en) 2014-02-25 2018-04-24 The United States Of America, As Represented By The Secretary Of Agriculture. Immunogenic composition
CN110295149B (en) * 2019-06-24 2022-06-24 四川农业大学 Mutant strain 3 type duck hepatitis A virus CH-P60-117C strain and construction method thereof

Citations (1)

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US5693530A (en) * 1994-01-11 1997-12-02 Cornell Research Foundation, Inc. Marek's disease virus nucleotide sequence and methods of use

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Also Published As

Publication number Publication date
US7029681B2 (en) 2006-04-18
EP1490105A2 (en) 2004-12-29
BR0308365A (en) 2005-09-06
WO2003075843A2 (en) 2003-09-18
BRPI0308365B1 (en) 2016-12-27
AU2003216531B2 (en) 2006-11-30
US20030175291A1 (en) 2003-09-18
IL163859A (en) 2010-05-17
IL163859A0 (en) 2005-12-18
EP1490105A4 (en) 2006-04-19
CN1646157B (en) 2011-03-02
CN101703770A (en) 2010-05-12
CN1646157A (en) 2005-07-27
EP1490105B1 (en) 2013-10-02
JP2009203242A (en) 2009-09-10
AU2003216531A1 (en) 2003-09-22
CA2478081A1 (en) 2003-09-18
JP2005519943A (en) 2005-07-07
CA2478081C (en) 2011-04-19
JP4999258B2 (en) 2012-08-15
MXPA04008692A (en) 2005-02-24

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