WO2005084534A8 - Personal diagnostic devices and related methods - Google Patents

Personal diagnostic devices and related methods

Info

Publication number
WO2005084534A8
WO2005084534A8 PCT/US2004/028964 US2004028964W WO2005084534A8 WO 2005084534 A8 WO2005084534 A8 WO 2005084534A8 US 2004028964 W US2004028964 W US 2004028964W WO 2005084534 A8 WO2005084534 A8 WO 2005084534A8
Authority
WO
WIPO (PCT)
Prior art keywords
chambers
diagnostic devices
bio
patches
bracelets
Prior art date
Application number
PCT/US2004/028964
Other languages
French (fr)
Other versions
WO2005084534A1 (en
Inventor
Brigitte Chau Phan
Andrew Atilla Pal
Ramoncito M Valencia
Donald Bollella
Original Assignee
Life Patch International Inc
Brigitte Chau Phan
Andrew Atilla Pal
Ramoncito M Valencia
Donald Bollella
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Patch International Inc, Brigitte Chau Phan, Andrew Atilla Pal, Ramoncito M Valencia, Donald Bollella filed Critical Life Patch International Inc
Priority to JP2006526215A priority Critical patent/JP2007503958A/en
Priority to AU2004317007A priority patent/AU2004317007A1/en
Priority to BRPI0414067-2A priority patent/BRPI0414067A/en
Priority to CA2537796A priority patent/CA2537796C/en
Priority to CN2004800320767A priority patent/CN1874720B/en
Priority to KR1020067006489A priority patent/KR101165102B1/en
Priority to EP04821543A priority patent/EP1670356A1/en
Publication of WO2005084534A1 publication Critical patent/WO2005084534A1/en
Publication of WO2005084534A8 publication Critical patent/WO2005084534A8/en
Priority to HK07105873.4A priority patent/HK1100761A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1112—Global tracking of patients, e.g. by using GPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
    • A61B5/14521—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat using means for promoting sweat production, e.g. heating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150213—Venting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150847—Communication to or from blood sampling device
    • A61B5/15087—Communication to or from blood sampling device short range, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/7475—User input or interface means, e.g. keyboard, pointing device, joystick
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/07—Home care
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
    • A61B2560/0412—Low-profile patch shaped housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/028—Microscale sensors, e.g. electromechanical sensors [MEMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0285—Nanoscale sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405—Devices for taking blood samples
    • A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using bluetooth
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers

Abstract

Personal diagnostic devices including diagnostic patches (bio-patches) and interactive medical bracelets (bio-bracelets) are provided with a skin/patch interface, at least one analysis layer, a signal processing layer, and a user output interface. Embodiments of the interactive diagnostic devices may include micro-fluidic circuits with reaction chambers, analysis chambers, mixing chambers, and various pre-disposed chemistries or reagents for performing a wide verity of tests by trans-dermal transport of blood or perspiration. Sample collection chambers for the fluidic circuit may include minimally invasive tubules that penetrate the skin surface to acquire blood samples from capillaries near the epidermis. Alternate implementations of the personal diagnostic device may be equipped with logic processing, input/output devices, acoustic microphones, cryogenic circuits, embedded processors, electrical control circuitry, and battery current sources or photovoltaic sources of electrical power.
PCT/US2004/028964 2003-09-03 2004-09-02 Personal diagnostic devices and related methods WO2005084534A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2006526215A JP2007503958A (en) 2003-09-03 2004-09-02 Personal diagnostic equipment and related methods
AU2004317007A AU2004317007A1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
BRPI0414067-2A BRPI0414067A (en) 2003-09-03 2004-09-02 personal diagnostic device and method of using the same
CA2537796A CA2537796C (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
CN2004800320767A CN1874720B (en) 2003-09-03 2004-09-02 Personal diagnostic devices
KR1020067006489A KR101165102B1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
EP04821543A EP1670356A1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods
HK07105873.4A HK1100761A1 (en) 2003-09-03 2007-06-04 Personal diagnostic devices

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50010203P 2003-09-03 2003-09-03
US60/500,102 2003-09-03
US51076903P 2003-10-11 2003-10-11
US60/510,769 2003-10-11

Publications (2)

Publication Number Publication Date
WO2005084534A1 WO2005084534A1 (en) 2005-09-15
WO2005084534A8 true WO2005084534A8 (en) 2005-10-20

Family

ID=34922618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/028964 WO2005084534A1 (en) 2003-09-03 2004-09-02 Personal diagnostic devices and related methods

Country Status (11)

Country Link
US (5) US9133024B2 (en)
EP (1) EP1670356A1 (en)
JP (1) JP2007503958A (en)
KR (1) KR101165102B1 (en)
CN (2) CN102018496A (en)
AU (1) AU2004317007A1 (en)
BR (1) BRPI0414067A (en)
CA (1) CA2537796C (en)
HK (1) HK1100761A1 (en)
SG (1) SG146630A1 (en)
WO (1) WO2005084534A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852101B2 (en) 2005-12-28 2014-10-07 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8862198B2 (en) 2006-09-10 2014-10-14 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9265453B2 (en) 2010-03-24 2016-02-23 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9402570B2 (en) 2011-12-11 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor devices, connections, and methods
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9480421B2 (en) 2005-09-30 2016-11-01 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices

Families Citing this family (295)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
CA2448902C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
DE60234597D1 (en) 2001-06-12 2010-01-14 Pelikan Technologies Inc DEVICE AND METHOD FOR REMOVING BLOOD SAMPLES
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7033371B2 (en) 2001-06-12 2006-04-25 Pelikan Technologies, Inc. Electric lancet actuator
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US6850788B2 (en) 2002-03-25 2005-02-01 Masimo Corporation Physiological measurement communications adapter
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
CA2537796C (en) * 2003-09-03 2013-12-03 Life Patch International, Inc. Personal diagnostic devices and related methods
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
CN1934444A (en) 2004-03-05 2007-03-21 艾格麦迪卡瑞士股份有限公司 Analyte test system for determining the concentration of an analyte in a physiological fluid
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
EP1776464B1 (en) * 2004-08-13 2009-10-07 Egomedical Technologies AG Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid
US8613703B2 (en) 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US20090082693A1 (en) * 2004-12-29 2009-03-26 Therasense, Inc. Method and apparatus for providing temperature sensor module in a data communication system
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006080024A2 (en) * 2005-01-31 2006-08-03 Given Imaging Ltd. Device, system and method for in vivo analysis
US7671398B2 (en) * 2005-02-23 2010-03-02 Tran Bao Q Nano memory, light, energy, antenna and strand-based systems and methods
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
KR101381331B1 (en) 2005-05-09 2014-04-04 테라노스, 인코포레이티드 Point-of-care fluidic systems and uses thereof
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
JP2009506331A (en) * 2005-08-31 2009-02-12 エゴメディカル テクノロジーズ アクチエンゲゼルシャフト Analyte inspection system using non-enzymatic analyte recognition components
EP1920246B1 (en) * 2005-08-31 2010-03-10 Egomedical Technologies AG Coagulation test system
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
WO2007041244A2 (en) 2005-09-30 2007-04-12 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US7499739B2 (en) * 2005-10-27 2009-03-03 Smiths Medical Pm, Inc. Single use pulse oximeter
US7486977B2 (en) 2005-10-27 2009-02-03 Smiths Medical Pm, Inc. Single use pulse oximeter
US20080241909A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for pathogen detection
US20080193919A1 (en) * 2005-11-30 2008-08-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems and methods for receiving pathogen related information and responding
US20080241910A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
US20080178692A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US20080179255A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic devices
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
CA2636034A1 (en) 2005-12-28 2007-10-25 Abbott Diabetes Care Inc. Medical device insertion
EP1977223B8 (en) * 2006-01-12 2013-05-15 MycroLab Diagnostics Pty Ltd Smart card with integrated microfluidic analysis
CN101416048B (en) * 2006-01-12 2013-10-02 迈克罗拉布诊断有限公司 New instrumentation systems and methods
US20090299213A1 (en) * 2006-03-15 2009-12-03 President And Fellows Of Harvard College Nanobioelectronics
US8920343B2 (en) 2006-03-23 2014-12-30 Michael Edward Sabatino Apparatus for acquiring and processing of physiological auditory signals
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8741230B2 (en) * 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US20100216657A1 (en) * 2006-05-16 2010-08-26 Arcxis Biotechnologies, Inc. Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
JP2009540333A (en) 2006-06-12 2009-11-19 プレジデント アンド フェロウズ オブ ハーバード カレッジ Nanosensors and related technologies
WO2008006153A1 (en) * 2006-07-11 2008-01-17 Paul Nigel Brockwell Medical indicator method and device
WO2008105814A2 (en) 2006-08-22 2008-09-04 Los Alamos National Security, Llc Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
US20080176755A1 (en) * 2006-08-25 2008-07-24 The Trustees Of Columbia University In The City Of New York, Office Of The General Counsel Systems and methods for biodosimetry with biochip using gene expression signatures
JP5382347B2 (en) * 2006-10-11 2014-01-08 フルイディウム コーポレーション Disposable micro purification card, method and system
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US8579853B2 (en) * 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
WO2008127314A1 (en) 2006-11-22 2008-10-23 President And Fellows Of Harvard College High-sensitivity nanoscale wire sensors
WO2008071218A1 (en) * 2006-12-14 2008-06-19 Egomedical Swiss Ag Monitoring device
US10001496B2 (en) * 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US8617903B2 (en) * 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US20080181816A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Systems for allergen detection
US20090050569A1 (en) * 2007-01-29 2009-02-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20080180259A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for allergen detection
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
WO2008092470A1 (en) * 2007-01-29 2008-08-07 Egomedical Swiss Ag Resealeable container for storing moisture sensitive test elements
US20080245740A1 (en) * 2007-01-29 2008-10-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US7821637B1 (en) 2007-02-22 2010-10-26 J.A. Woollam Co., Inc. System for controlling intensity of a beam of electromagnetic radiation and method for investigating materials with low specular reflectance and/or are depolarizing
US20090227005A1 (en) * 2007-03-27 2009-09-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US20080275326A1 (en) * 2007-05-01 2008-11-06 Joachim Kasielke Sensor for monitoring a condition of a patient
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
CN103323610B (en) 2007-10-02 2016-12-28 赛拉诺斯股份有限公司 Modular point-of-care devices and application thereof
EP2056114A1 (en) * 2007-10-29 2009-05-06 Koninklijke Philips Electronics N.V. Automatic detection of infectious diseases
JP5374861B2 (en) 2007-11-09 2013-12-25 オムロンヘルスケア株式会社 Blood component concentration measuring device and method for controlling blood component concentration measuring device
JP4952525B2 (en) * 2007-11-09 2012-06-13 オムロンヘルスケア株式会社 Blood component concentration measuring apparatus and blood component concentration measuring method
JP5186887B2 (en) * 2007-11-09 2013-04-24 オムロンヘルスケア株式会社 Blood component concentration measuring apparatus and blood component concentration measuring method
KR20090092506A (en) * 2008-02-27 2009-09-01 케이엠에이치 주식회사 Glucose measuring system
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
JP2011522521A (en) * 2008-05-05 2011-08-04 ロスアラモス ナショナル セキュリティ，エルエルシー Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
EP2293719B1 (en) 2008-05-30 2015-09-09 Intuity Medical, Inc. Body fluid sampling device -- sampling site interface
US10383556B2 (en) 2008-06-06 2019-08-20 Intuity Medical, Inc. Medical diagnostic devices and methods
CA2726067C (en) 2008-06-06 2020-10-20 Intuity Medical, Inc. Detection meter and mode of operation
CN102132281B (en) * 2008-08-28 2016-02-03 皇家飞利浦电子股份有限公司 Sensor for wearing for patient provides the method and system of patient's identification beacon
US20100130843A1 (en) * 2008-11-24 2010-05-27 Tecnicas Cientificas Para Laboratorio, S.A Wireless device for confirmatory diagnosis of cystic fibrosis through analysis of sweat chloride
US20100137575A1 (en) * 2008-12-03 2010-06-03 Connolly D Michael Universal biological sample processing
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100198188A1 (en) * 2009-02-05 2010-08-05 Abbott Diabetes Care Inc. Devices and Methods for Metering Insoluble Active Agent Particles
US9119578B2 (en) 2011-04-29 2015-09-01 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
JP6078230B2 (en) 2009-03-02 2017-02-08 セブンス センス バイオシステムズ，インコーポレーテッド Techniques and devices related to blood sampling
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US20110105951A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US20110046466A1 (en) * 2009-08-19 2011-02-24 Feldman Benjamin J Analyte Sensors Including Nanomaterials and Methods of Using Same
CA2765712A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Medical devices and methods
DE102009029215A1 (en) * 2009-09-04 2011-03-10 Robert Bosch Gmbh Device for determining body functions
WO2011038228A1 (en) 2009-09-24 2011-03-31 President And Fellows Of Harvard College Bent nanowires and related probing of species
US8862448B2 (en) 2009-10-19 2014-10-14 Theranos, Inc. Integrated health data capture and analysis system
EP3257442A3 (en) * 2009-10-30 2018-05-09 Seventh Sense Biosystems, Inc. Relatively small devices applied to the skin, modular systems, and methods of use thereof
US8919605B2 (en) 2009-11-30 2014-12-30 Intuity Medical, Inc. Calibration material delivery devices and methods
WO2011091473A1 (en) * 2010-01-28 2011-08-04 Respirio Pty Ltd Sampling and testing device for the human or animal body
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011162823A1 (en) 2010-06-25 2011-12-29 Intuity Medical, Inc. Analyte monitoring methods and systems
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
KR102173440B1 (en) * 2010-06-30 2020-11-03 앤팩 바이오-메디컬 사이언스 시오., 엘티디. Apparatus for disease detection
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
EP2596347B1 (en) 2010-07-22 2017-09-06 Hach Company Alkalinity analysis using a lab-on-a-chip
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2992827B1 (en) 2010-11-09 2017-04-19 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
CN106323876B (en) 2011-01-21 2020-02-14 西拉诺斯知识产权有限责任公司 System and method for maximizing sample usage
US20120197621A1 (en) * 2011-01-31 2012-08-02 Fujitsu Limited Diagnosing Insulin Resistance
US20120197622A1 (en) * 2011-01-31 2012-08-02 Fujitsu Limited Monitoring Insulin Resistance
US9488613B2 (en) * 2011-03-02 2016-11-08 Massachusetts Institute Of Technology Systems, devices and methods for multiplexed diagnostics
JP2014508950A (en) * 2011-03-25 2014-04-10 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Body fluid analysis device
US8911941B2 (en) * 2011-04-14 2014-12-16 Kenneth J. Michlitsch Methods and apparatus for point-of-care nucleic acid amplification and detection
US9469871B2 (en) 2011-04-14 2016-10-18 Corporos Inc. Methods and apparatus for point-of-care nucleic acid amplification and detection
KR101508670B1 (en) 2011-04-20 2015-04-07 메사 테크 인터내셔널, 인코포레이티드 Integrated device for nucleic acid detection and identification
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
GB2491813A (en) * 2011-06-03 2012-12-19 Univ Dublin City A microfluidic device with sacrificial valve
US9595685B2 (en) 2011-06-10 2017-03-14 President And Fellows Of Harvard College Nanoscale wires, nanoscale wire FET devices, and nanotube-electronic hybrid devices for sensing and other applications
EP3750480B1 (en) 2011-08-03 2022-02-02 Intuity Medical, Inc. Body fluid sampling arrangement
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8840838B2 (en) 2011-09-25 2014-09-23 Theranos, Inc. Centrifuge configurations
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US20140295415A1 (en) * 2011-11-04 2014-10-02 Diagnostics For All, Inc. Low cost, disposable molecular diagnostic devices
WO2013099629A1 (en) * 2011-12-27 2013-07-04 ソニー株式会社 Information processing device and method
AU2013243541B2 (en) 2012-04-04 2017-04-06 United States Of America As Represented By The Secretary Of The Air Force Sweat simulation, collection and sensing systems
US9822356B2 (en) * 2012-04-20 2017-11-21 California Institute Of Technology Fluidic devices and systems for sample preparation or autonomous analysis
US9354159B2 (en) 2012-05-02 2016-05-31 Nanoscopia (Cayman), Inc. Opto-fluidic system with coated fluid channels
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
US9523865B2 (en) 2012-07-26 2016-12-20 Verily Life Sciences Llc Contact lenses with hybrid power sources
US10890590B2 (en) 2012-09-27 2021-01-12 Ellume Limited Diagnostic devices and methods
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
US9759672B2 (en) * 2012-12-19 2017-09-12 James Francis Ziegler Radiation detecting wearable devices
DK2941195T3 (en) * 2013-01-02 2017-03-06 Fibrotx Oü Device for measuring analytes in the skin
EP2762066A1 (en) * 2013-02-05 2014-08-06 Koninklijke Philips N.V. System and method for determining vital sign information of a subject
US20140323819A1 (en) * 2013-04-29 2014-10-30 Elwha LLC, a limited liability company of the State of Delaware Multi-parameter test units for initial indication of medical symptoms
WO2014205412A1 (en) 2013-06-21 2014-12-24 Intuity Medical, Inc. Analyte monitoring system with audible feedback
WO2015009970A1 (en) 2013-07-18 2015-01-22 Erythron Llc Spectroscopic measurements with parallel array detector
US10422806B1 (en) 2013-07-25 2019-09-24 Theranos Ip Company, Llc Methods for improving assays of biological samples
CN103445763B (en) * 2013-08-26 2015-08-26 华中科技大学 A kind of health monitoring systems based on epidermis electronics
US20150064672A1 (en) * 2013-09-05 2015-03-05 Matthew Bars Systems and methods for treatment of substance addiction
US8742623B1 (en) 2013-09-16 2014-06-03 Google Inc. Device with dual power sources
WO2015044454A2 (en) * 2013-09-30 2015-04-02 Göran Stemme A microfluidic device, use and methods
CN110477861B (en) 2013-10-18 2023-02-03 辛辛那提大学 Sweat sensing in a chronological assurance manner
US10888244B2 (en) 2013-10-18 2021-01-12 University Of Cincinnati Sweat sensing with chronological assurance
EP3057490B1 (en) 2013-10-18 2022-05-25 University of Cincinnati Devices for integrated, repeated, prolonged, and/or reliable sweat stimulation and biosensing
US20150173674A1 (en) * 2013-12-20 2015-06-25 Diabetes Sentry Products Inc. Detecting and communicating health conditions
US20150338338A1 (en) 2014-02-28 2015-11-26 Erythron, Llc Method and Apparatus for Determining Markers of Health by Analysis of Blood
AU2015247338B2 (en) 2014-04-17 2020-10-08 Z-Integrated Digital Technologies, Inc. Electronic test device data communication
US10413565B2 (en) 2014-04-30 2019-09-17 Northwestern University Nanostructures for modulating intercellular communication and uses thereof
CN106793969A (en) 2014-05-28 2017-05-31 辛辛那提大学 The device of the sweat volume with the reduction between sensor and sweat gland
EP3148430A4 (en) 2014-05-28 2018-05-16 University of Cincinnati Advanced sweat sensor adhesion, sealing, and fluidic strategies
US11129554B2 (en) 2014-05-28 2021-09-28 University Of Cincinnati Sweat monitoring and control of drug delivery
US10736551B2 (en) * 2014-08-11 2020-08-11 The Board Of Trustees Of The University Of Illinois Epidermal photonic systems and methods
CN107205643B (en) 2014-09-22 2021-11-23 辛辛那提大学 Sweat sensing with analytical assurance
CN107249451A (en) 2014-10-15 2017-10-13 外分泌腺系统公司 Sweat sensing device communications security and compliance
CN104434063A (en) * 2014-11-24 2015-03-25 深圳市华宝电子科技有限公司 Remote real-time monitoring system
KR20160089718A (en) 2015-01-20 2016-07-28 삼성전자주식회사 Sensor module and wearable analyzing device for body compositon with the same
WO2016115608A1 (en) 2015-01-22 2016-07-28 Ellume Pty Ltd Diagnostic devices and methods for mitigating hook effect and use thereof
WO2016130905A1 (en) 2015-02-13 2016-08-18 University Of Cincinnati Devices for integrated indirect sweat stimulation and sensing
US10477354B2 (en) 2015-02-20 2019-11-12 Mc10, Inc. Automated detection and configuration of wearable devices based on on-body status, location, and/or orientation
US11389087B2 (en) 2015-03-09 2022-07-19 CoreSyte, Inc. Device for measuring biological fluids
US10561405B2 (en) * 2015-03-09 2020-02-18 CoreSyte, Inc. Method for manufacturing a biological fluid sensor
US11883011B2 (en) * 2015-03-09 2024-01-30 CoreSyte, Inc. Method for manufacturing a biological fluid sensor
WO2016168090A1 (en) 2015-04-14 2016-10-20 Nueon, Inc. Method and apparatus for determining markers of health by analysis of blood
WO2016183493A1 (en) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
US20160367194A1 (en) * 2015-05-14 2016-12-22 Richard Murphy Illumination system for mobile devices
CN107567306B (en) * 2015-05-14 2020-06-26 通用电气公司 Device for separation and collection of plasma
US11260386B2 (en) * 2015-06-05 2022-03-01 The Emerther Company Component of a device, a device, and a method for purifying and testing biomolecules from biological samples
US10646142B2 (en) 2015-06-29 2020-05-12 Eccrine Systems, Inc. Smart sweat stimulation and sensing devices
US10105100B2 (en) * 2015-07-28 2018-10-23 Verily Life Sciences Llc Display on a bandage-type monitoring device
US20170103669A1 (en) * 2015-10-09 2017-04-13 Fuji Xerox Co., Ltd. Computer readable recording medium and system for providing automatic recommendations based on physiological data of individuals
EP3364862A4 (en) 2015-10-23 2019-10-23 Eccrine Systems, Inc. Devices capable of sample concentration for extended sensing of sweat analytes
US10674946B2 (en) 2015-12-18 2020-06-09 Eccrine Systems, Inc. Sweat sensing devices with sensor abrasion protection
EP3410127A4 (en) * 2016-01-25 2019-08-28 Kyocera Corporation Measurement sensor package and measurement sensor
US10277386B2 (en) 2016-02-22 2019-04-30 Mc10, Inc. System, devices, and method for on-body data and power transmission
US11039986B2 (en) 2016-02-25 2021-06-22 Samsung Electronics Co., Ltd. Chronotherapeutic dosing of medication and medication regimen adherence
WO2017165403A1 (en) 2016-03-21 2017-09-28 Nueon Inc. Porous mesh spectrometry methods and apparatus
MX2018011801A (en) 2016-03-30 2019-12-16 Convatec Technologies Inc Detecting microbial infections in wounds.
CN109310340A (en) * 2016-04-19 2019-02-05 Mc10股份有限公司 For measuring the method and system of sweat
EP3454723A1 (en) * 2016-05-09 2019-03-20 King Abdullah University Of Science And Technology Wearable personalized medicinal platform
US10471249B2 (en) 2016-06-08 2019-11-12 University Of Cincinnati Enhanced analyte access through epithelial tissue
US11253190B2 (en) 2016-07-01 2022-02-22 University Of Cincinnati Devices with reduced microfluidic volume between sensors and sweat glands
WO2018013579A1 (en) * 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
US10405794B2 (en) 2016-07-19 2019-09-10 Eccrine Systems, Inc. Sweat conductivity, volumetric sweat rate, and galvanic skin response devices and applications
EP3272285B1 (en) * 2016-07-20 2019-06-05 Techkon GmbH Device and method for measuring variables or parameters of a bodily fluid
JP6689699B2 (en) 2016-07-22 2020-04-28 シスメックス株式会社 Blood collection tool and blood collection set
US10447347B2 (en) 2016-08-12 2019-10-15 Mc10, Inc. Wireless charger and high speed data off-loader
US11389096B2 (en) * 2016-09-10 2022-07-19 Ecole Polytechnique Federale De Lausanne (Epfl) Bio-fluid collection and sensing device, system and method
EP3513200A4 (en) * 2016-09-15 2020-07-29 Northwestern University Nanoparticles as catalytic substrates for real-time biosensing of human performance and diagnostic and therapeutic methods
US10736565B2 (en) 2016-10-14 2020-08-11 Eccrine Systems, Inc. Sweat electrolyte loss monitoring devices
WO2018085699A1 (en) 2016-11-04 2018-05-11 Nueon Inc. Combination blood lancet and analyzer
DE112016007510T5 (en) * 2016-12-08 2019-09-26 Intel Corporation BODY-PORTABLE ASSAY SYSTEM AND USE METHOD
CN115444410A (en) 2017-01-23 2022-12-09 雅培糖尿病护理公司 Applicator and assembly for inserting an in vivo analyte sensor
EP3357422A1 (en) * 2017-02-07 2018-08-08 Koninklijke Philips N.V. Microneedles and insertable devices with integrated antenna array
US20180256111A1 (en) * 2017-03-07 2018-09-13 Primus Llc Apparatus and method to record health care vitals and information on a stand-alone and mobile device.
WO2019023195A1 (en) * 2017-07-25 2019-01-31 Epicore Biosystems, Inc. Wearable fluidic system for measuring sweat composition
US11709468B2 (en) * 2017-07-25 2023-07-25 Life Patch International User comfort control system having non-invasive bio-patch
CN111212596A (en) 2017-08-17 2020-05-29 逻辑英克公司 Tag for sensing airborne particulate contamination by wearable colorimetry
TWI644101B (en) * 2017-08-29 2018-12-11 瑞瑩生醫科技股份有限公司 A test strip for electrochemical biosensor with high stability and manufacturing method thereof
US10123702B1 (en) 2017-08-31 2018-11-13 Jennifer Wilkins Patient monitoring system
US11723579B2 (en) 2017-09-19 2023-08-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
FR3072270B1 (en) * 2017-10-13 2020-01-31 Devinnova SKIN SURVEILLANCE SYSTEM FOR AN INDIVIDUAL
US11331009B2 (en) 2017-10-16 2022-05-17 Xsensio SA Apparatus for non-invasive sensing of biomarkers in human sweat
KR102399533B1 (en) * 2017-10-18 2022-05-19 삼성전자주식회사 Electronic device and method for providing stress index corresponding to activity of user
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11478603B2 (en) 2017-12-31 2022-10-25 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11060968B2 (en) * 2018-03-30 2021-07-13 International Business Machines Corporation Mobile chemical analysis
US11585882B2 (en) 2018-04-11 2023-02-21 Mars Sciences Limited Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
CN109199400B (en) * 2018-09-10 2021-08-31 中山大学 Blood glucose electrochemical sensor based on microneedle array
EP3849410A4 (en) 2018-09-14 2022-11-02 Neuroenhancement Lab, LLC System and method of improving sleep
US11285482B2 (en) 2018-09-21 2022-03-29 Lockheed Martin Corporation Molecular sensing device
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
JP2022537884A (en) * 2019-06-21 2022-08-31 ユニスト（ウルサン ナショナル インスティテュート オブ サイエンス アンド テクノロジー） Biosensors using resonator assemblies and electromagnetic waves for biosensing
AU2020328540A1 (en) 2019-08-12 2022-03-03 Efferent Labs, Inc. Wearable devices for monitoring physiological changes and methods of use
CN110824157B (en) * 2019-11-14 2023-03-31 广州科方生物技术股份有限公司 Method for quickly separating red blood cells for immunochromatography detection kit
TWI746015B (en) * 2019-12-09 2021-11-11 財團法人工業技術研究院 Wearable measurement device and method of measuring a biological target using the same
KR102309531B1 (en) * 2020-01-29 2021-10-07 성균관대학교산학협력단 Microfluidic device for detecting biomolecules in sweat and wearable biosensor patch using the same
WO2021163347A1 (en) * 2020-02-11 2021-08-19 Life Patch International Wearable patches for sports
EP4164492A1 (en) * 2020-06-16 2023-04-19 Ben-Bashat Bergman, Liron Whole blood sampling and monitoring device, method and software
CN111657875B (en) * 2020-07-09 2021-01-29 深圳市则成电子股份有限公司 Blood oxygen testing method, device and storage medium thereof
US11898197B2 (en) 2020-07-30 2024-02-13 Wainamics, Inc. System and self-metering cartridges for point of care bioassays
US11904314B2 (en) * 2020-07-30 2024-02-20 Wainamics, Inc. System and self-metering cartridges for point of care bioassays
US11734966B1 (en) 2020-10-15 2023-08-22 Ethernovia Inc. Recursive system layer analysis for achieving functional safety
US11803180B2 (en) 2020-10-15 2023-10-31 Ethernovia Inc. Determining diagnostic coverage for achieving functional safety
WO2022109390A1 (en) * 2020-11-22 2022-05-27 Gattaco Inc. Sample transfer devices, and components and methods thereof
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
CN117794456A (en) * 2021-05-19 2024-03-29 萨蒂奥股份有限公司 Free standing skin patch for blood analysis
CN113576450A (en) * 2021-07-16 2021-11-02 广州医科大学附属第一医院 Cough monitoring device and cough monitoring system
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
WO2023085780A1 (en) * 2021-11-09 2023-05-19 엘지전자 주식회사 Mobile terminal
CN116824579B (en) * 2023-06-27 2023-12-22 长沙金域医学检验实验室有限公司 Method and device for detecting yarrowia pneumocystis based on direct immunofluorescence staining

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
US3940475A (en) * 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
US3874852A (en) 1974-07-05 1975-04-01 Coulter Diagnostics Inc Reagent and method for determining leukocytes and hemoglobin in the blood
CA1056746A (en) * 1974-09-06 1979-06-19 Chung J. Lai Biologically active membrane material
US4286963A (en) 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4846182A (en) * 1982-01-11 1989-07-11 Medtronic, Inc. Method of preparing a fluid absorbent quantitative test device
US4528274A (en) * 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4751179A (en) 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US4732153A (en) * 1984-07-18 1988-03-22 Michael Phillips Transdermal dosimeter
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5114864A (en) * 1986-06-25 1992-05-19 Trustees Of Tufts College Fiber optic sensors, apparatus, and detection methods using fluid erodible controlled release polymers for delivery of reagent formulations
IL85532A (en) * 1987-03-13 1992-03-29 Coulter Electronics Method and lytic reagent system for isolation,identification and/or analysis of leukocytes from whole blood samples
US4821733A (en) 1987-08-18 1989-04-18 Dermal Systems International Transdermal detection system
US5465713A (en) * 1988-09-08 1995-11-14 Sudor Partners Energy-assisted transdermal collection patch for accelerated analyte collection and method of use
US5231015A (en) 1989-10-18 1993-07-27 Eastman Kodak Company Methods of extracting nucleic acids and pcr amplification without using a proteolytic enzyme
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5443080A (en) * 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
US5787885A (en) * 1994-10-13 1998-08-04 Lemelson; Jerome H. Body fluid analysis system
US6071249A (en) 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
JPH10305016A (en) 1997-05-08 1998-11-17 Casio Comput Co Ltd Behavior information providing system
ATE308924T1 (en) * 1998-02-17 2005-11-15 Abbott Lab DEVICE FOR SAMPLING AND ANALYZING INTERSTITIAL FLUID
US6479015B1 (en) * 1998-03-03 2002-11-12 Pepex Biomedical, Llc Apparatus for monitoring a level of a chemical species in a body fluid
WO1999058051A1 (en) * 1998-05-13 1999-11-18 Cygnus, Inc. Monitoring of physiological analytes
US6393318B1 (en) * 1998-05-13 2002-05-21 Cygnus, Inc. Collection assemblies, laminates, and autosensor assemblies for use in transdermal sampling systems
EP1086214B1 (en) * 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
MXPA01000698A (en) * 1998-07-21 2002-04-08 Spectrx Inc System and method for continuous analyte monitoring.
DE19848112C2 (en) 1998-10-19 2001-12-13 Meinhard Knoll Minimally invasive sensor system
US6424847B1 (en) * 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6223074B1 (en) * 1999-08-10 2001-04-24 Thuris Corporation Method and computer program product for assessing neurological conditions and treatments using evoked response potentials
US6251083B1 (en) * 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US7171251B2 (en) * 2000-02-01 2007-01-30 Spo Medical Equipment Ltd. Physiological stress detector device and system
AU6501201A (en) * 2000-06-01 2001-12-11 Science Applic Int Corp Systems and methods for monitoring health and delivering drugs transdermally
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
AU2001280615A1 (en) * 2000-07-18 2002-01-30 Healthetech, Inc. Closed loop glycemic index system
US6553244B2 (en) 2000-08-18 2003-04-22 Cygnus, Inc. Analyte monitoring device alarm augmentation system
US6585646B2 (en) * 2000-11-29 2003-07-01 Hermetic Diagnostics, Inc. Screening test and procedure using skin patches
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US6453928B1 (en) * 2001-01-08 2002-09-24 Nanolab Ltd. Apparatus, and method for propelling fluids
MXPA03008935A (en) * 2001-03-30 2004-06-30 Univ California Methods of fabricating nanostructures and nanowires and devices fabricated therefrom.
EP1262559A1 (en) 2001-06-01 2002-12-04 SIRS-Lab GmbH Dermal patch for detecting lactate
US20030208113A1 (en) * 2001-07-18 2003-11-06 Mault James R Closed loop glycemic index system
US20040094733A1 (en) * 2001-08-31 2004-05-20 Hower Robert W. Micro-fluidic system
US6723077B2 (en) * 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
US7004928B2 (en) * 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7364896B2 (en) * 2002-10-31 2008-04-29 Agilent Technologies, Inc. Test strips including flexible array substrates and method of hybridization
CA2537796C (en) * 2003-09-03 2013-12-03 Life Patch International, Inc. Personal diagnostic devices and related methods

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9480421B2 (en) 2005-09-30 2016-11-01 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
USD979766S1 (en) 2005-09-30 2023-02-28 Abbott Diabetes Care Inc. Analyte sensor device
US9332933B2 (en) 2005-12-28 2016-05-10 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8852101B2 (en) 2005-12-28 2014-10-07 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8862198B2 (en) 2006-09-10 2014-10-14 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9265453B2 (en) 2010-03-24 2016-02-23 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9402570B2 (en) 2011-12-11 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor devices, connections, and methods

Also Published As

Publication number Publication date
HK1100761A1 (en) 2007-09-28
US20180344230A1 (en) 2018-12-06
KR101165102B1 (en) 2012-07-12
US20050106713A1 (en) 2005-05-19
US20160066828A1 (en) 2016-03-10
US9993189B2 (en) 2018-06-12
CA2537796C (en) 2013-12-03
US11737694B2 (en) 2023-08-29
BRPI0414067A (en) 2006-10-24
KR20060123103A (en) 2006-12-01
AU2004317007A2 (en) 2005-09-15
US9133024B2 (en) 2015-09-15
CN1874720A (en) 2006-12-06
US20240090804A1 (en) 2024-03-21
WO2005084534A1 (en) 2005-09-15
EP1670356A1 (en) 2006-06-21
JP2007503958A (en) 2007-03-01
CA2537796A1 (en) 2005-09-15
SG146630A1 (en) 2008-10-30
CN102018496A (en) 2011-04-20
CN1874720B (en) 2010-11-17
AU2004317007A1 (en) 2005-09-15
US20160058354A1 (en) 2016-03-03

Similar Documents

Publication Publication Date Title
WO2005084534A8 (en) Personal diagnostic devices and related methods
MXPA02007421A (en) Devices for analyte concentration determination and methods of using the same.
TW200612867A (en) Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
CA2351796A1 (en) Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
MX2007013521A (en) Metering technique for lateral flow assay devices.
WO2004098376A3 (en) System, method and apparatus for measuring blood flow and blood volume
WO2012078650A3 (en) Transdermal sampling and analysis device
CN104107057B (en) Biofluid sampling transfer device and biofluid separate and test system
DK1766400T3 (en) Procedure for performing whole blood assays
WO2004042364A3 (en) Assay device, system and method
AU2002358128A1 (en) Method and device for monitoring analyte concentration by optical detection
DE602005022282D1 (en) PORTABLE WIRELESS DEVICE FOR MONITORING, ANALYSIS AND COMMUNICATION OF THE PHYSIOLOGICAL STATUS
DK1437091T3 (en) Determination of biological states using impedance measurements
TW200600060A (en) Apparatus for the manufacture of medical devices
SG119221A1 (en) Devices systems and methods for extracting bodily fluid and monitoring an analyte therein
WO2007075919A3 (en) Portable sample analyzer system
AU2002320094A1 (en) Integrated blood sampling analysis system with multi-use sampling module
MXPA02009563A (en) Method and device for sampling and analyzing interstitial fluid and whole blood samples.
WO2007075922A3 (en) Portable sample analyzer cartridge
WO2006065118A3 (en) Chromatographic analyse-devices and test kits
WO2006079062A8 (en) Analysis of auscultatory sounds using voice recognition
ATE513057T1 (en) BIOSENSOR AND ITS PRODUCTION
WO2006116917A3 (en) Devices and methods for sample collection and analysis
DE602004021775D1 (en) abrading
WO2010011690A3 (en) Self-automated titration system and method

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200480032076.7

Country of ref document: CN

AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WR Later publication of a revised version of an international search report
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006526215

Country of ref document: JP

Ref document number: 2537796

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004317007

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 1526/DELNP/2006

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2004821543

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 1020067006489

Country of ref document: KR

ENP Entry into the national phase

Ref document number: 2004317007

Country of ref document: AU

Date of ref document: 20040902

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004317007

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004821543

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0414067

Country of ref document: BR

WWP Wipo information: published in national office

Ref document number: 1020067006489

Country of ref document: KR