WO2005124360A3 - Use of protein tebp as a marker for breast cancer - Google Patents

Use of protein tebp as a marker for breast cancer Download PDF

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Publication number
WO2005124360A3
WO2005124360A3 PCT/EP2005/006526 EP2005006526W WO2005124360A3 WO 2005124360 A3 WO2005124360 A3 WO 2005124360A3 EP 2005006526 W EP2005006526 W EP 2005006526W WO 2005124360 A3 WO2005124360 A3 WO 2005124360A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast cancer
tebp
protein
marker
diagnosis
Prior art date
Application number
PCT/EP2005/006526
Other languages
French (fr)
Other versions
WO2005124360A2 (en
Inventor
Gabriele Pestlin
Herbert Andres
Peter Berndt
Marie-Luise Hagmann
Johann Karl
Hanno Langen
Michael Thierolf
Werner Zolg
Original Assignee
Roche Diagnostics Gmbh
Hoffmann La Roche
Gabriele Pestlin
Herbert Andres
Peter Berndt
Marie-Luise Hagmann
Johann Karl
Hanno Langen
Michael Thierolf
Werner Zolg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Hoffmann La Roche, Gabriele Pestlin, Herbert Andres, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Michael Thierolf, Werner Zolg filed Critical Roche Diagnostics Gmbh
Publication of WO2005124360A2 publication Critical patent/WO2005124360A2/en
Publication of WO2005124360A3 publication Critical patent/WO2005124360A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/99—Isomerases (5.)

Abstract

The present invention relates to the diagnosis of breast cancer. It discloses the use of protein TEBP (telomerase-binding protein p23) in the diagnosis of breast cancer. It relates to a method for diagnosis of breast cancer from a liquid sample, derived from an individual by measuring TEBP in said sample. Measurement of TEBP can, e.g., be used in the early detection or diagnosis of breast cancer.
PCT/EP2005/006526 2004-06-18 2005-06-17 Use of protein tebp as a marker for breast cancer WO2005124360A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04014314 2004-06-18
EP04014314.1 2004-06-18

Publications (2)

Publication Number Publication Date
WO2005124360A2 WO2005124360A2 (en) 2005-12-29
WO2005124360A3 true WO2005124360A3 (en) 2006-05-26

Family

ID=35510375

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/006526 WO2005124360A2 (en) 2004-06-18 2005-06-17 Use of protein tebp as a marker for breast cancer

Country Status (1)

Country Link
WO (1) WO2005124360A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798266A (en) * 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US5952175A (en) * 1997-10-09 1999-09-14 Incyte Pharmaceuticals, Inc. DNA encoding a human progesterone receptor complex p23-like protein
WO2001029235A2 (en) * 1999-10-18 2001-04-26 Emory University Tms1 compositions and methods of use
WO2004009622A2 (en) * 2002-07-19 2004-01-29 Cellzome Ag Protein complexes of cellular networks underlying the development of cancer and other diseases
WO2004111650A1 (en) * 2003-06-06 2004-12-23 Roche Diagnostics Gmbh Use of protein cellular retinoic acid-binding protein ii (crabp ii) as marker for breast cancer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798266A (en) * 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US5952175A (en) * 1997-10-09 1999-09-14 Incyte Pharmaceuticals, Inc. DNA encoding a human progesterone receptor complex p23-like protein
WO2001029235A2 (en) * 1999-10-18 2001-04-26 Emory University Tms1 compositions and methods of use
WO2004009622A2 (en) * 2002-07-19 2004-01-29 Cellzome Ag Protein complexes of cellular networks underlying the development of cancer and other diseases
WO2004111650A1 (en) * 2003-06-06 2004-12-23 Roche Diagnostics Gmbh Use of protein cellular retinoic acid-binding protein ii (crabp ii) as marker for breast cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KNOBLAUCH R. ET AL.: "Role for Hsp90-associated cochaperone p23 in estrogen receptor signal transduction.", MOL. CELL. BIOL., vol. 19, no. 5, May 1999 (1999-05-01), pages 3748 - 3759, XP002368883 *
OXELMARK E. ET AL.: "Genetic dissection of p23, an Hsp90 cochaperone, reveals a distinct surface involved in estrogen receptor signaling.", J. BIOL. CHEM., vol. 278, no. 38, 19 September 2003 (2003-09-19), pages 36547 - 36555, XP002368884 *

Also Published As

Publication number Publication date
WO2005124360A2 (en) 2005-12-29

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