Classifications

• • A61F13/05—
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
  • A61M1/91—Suction aspects of the dressing
  • A61M1/915—Constructional details of the pressure distribution manifold
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
  • A61M1/91—Suction aspects of the dressing
  • A61M1/918—Suction aspects of the dressing for multiple suction locations

Definitions

• the present invention relates to the field of medical wound treatment devices, and more particularly to a multilayer foam dressing for negative pressure closed drainage and a method of making the same. Background technique
• Vacuum sealing drainage was initiated in 1992 by Dr. Wim Fleischman of ULM University in Germany, and formed a theoretical prototype for the drainage of limbs.
• Professor Yan Huade of China applied the application of vacuum sealing technology for the first time. Yupu Surgery pioneered the application of negative pressure closed drainage technology in general surgery.
• Professor Wang Yanfeng and Prof. Hua Huade were granted the patent CN 2236350 on March 17, 1997, which is the first patent for vacuum sealing drainage technology.
• the basic configuration of the existing VSD technology includes a negative pressure source (including a medical suction machine, a central negative pressure device used in a hospital or a negative pressure drainage bottle, etc.), a drainage tube, a hydrophilic foam material or other medical hydrophobic foam material or sponge.
• the dressing or gauze dressing hereinafter referred to as the above-mentioned medical material collectively referred to as porous foam material
• the sealing film can be adhered, and the drainage container is composed.
• the above technology can directly excrete necrotic tissue and toxins, pus, etc., avoid re-absorption of toxins, and quickly clean the wound surface; at the same time, high vacuum suction can effectively promote the rapid growth of granulation and shorten the wound healing time.
• patients can change their medication within 3-7 days, avoid cross-infection, reduce the workload of medical staff, reduce patient suffering, and reduce the mortality and disability rate of trauma.
• VSD technology is mainly realized by relying on porous foam cushions as medical polymer dressings.
• This dressing is both a negative pressure transmission medium and a drainage medium for introducing necrotic tissue, pus, exudate, other toxic products and toxins into the drainage tube.
• foam dressings for negative pressure closed drainage on the market: hydrophobic dressings and hydrophilic dressings.
• Hydrophobic dressings are mostly made of PU materials, which have larger foam pores and higher permeability. Because of their hydrophobic nature, the foams generally do not contain water, so the negative pressure conduction performance is excellent.
• Most of the hydrophilic dressings are foamed with PVA material.
• the foam pores are smaller than the hydrophobic dressings, and the material permeability is low, but it can also meet the negative pressure drainage treatment. Need; Because of its hydrophilic nature, a layer of water molecules will form on the surface of the dressing, which will directly contact the endothelial cells of the dressing and granulation tissue, prevent the granulation tissue from growing into the dressing, avoid pulling bleeding, and the material is extremely safe. high.
• both of the above dressings have drawbacks in clinical applications. Due to its hydrophobic nature, the hydrophobic dressing (PU) has no protective layer on the surface of the material. The granulation tissue can grow into the pores of the foam, which is prone to pulling bleeding. It is also difficult due to the poor tensile strength of the hydrophobic dressing (PU). The debris is detached, which in turn causes the foreign body inflammatory reaction (rejection) and secondary infection of the wound cavity, so there is a big problem in material safety.
• the US FDA report shows that with PU dressings, patients have death and aggravated trauma.
• PU dressings have a short dressing period (US FDA report and related literature shows that it can not exceed three days), the cost is high, the labor intensity of medical staff is large, and patients are more painful.
• Hydrophilic dressing Due to its hydrophilic nature, the material itself is moist, although its permeability is low, it can also meet the treatment requirements of negative pressure drainage, but because of the water content of the material, its negative pressure conduction performance is better. Poor, it is easy to produce negative pressure conduction weak area when using large area wounds. Secondly, PVA material gradually becomes dry gradually after water loss, which leads to further decrease of permeability and weakening treatment effect. Summary of the invention
• the technical problem to be solved by the present invention is to provide a multi-layered foam dressing for negative pressure closed drainage and a manufacturing method thereof, which can overcome the defects of the existing negative pressure closed drainage dressing, and can effectively improve the safety of the material while ensuring the safety of the material. Its negative pressure conduction performance, and it is not easy to block during use, the permeability is stable, and the treatment effect is excellent.
• a multi-layered foam dressing for negative pressure closed drainage includes a negative pressure conducting layer, and a drainage protective layer for contacting a wound or a wound cavity is disposed at a lower portion of the negative pressure conducting layer.
• the negative pressure conductive layer and the drainage protective layer are both porous foam layers; the negative pressure conductive layer is a hydrophobic porous foam material layer, and the drainage protective layer is a hydrophilic porous foam material layer, and the two layers are fixed between Connected and the pores are in contact with each other.
• the negative pressure conductive layer has a thickness a of 0.5 to 10 cm, a pore diameter of 1 to 2.5 mm, a thickness b of the drainage protective layer of 0.1 to 3.5 cm, and a pore diameter of 0.2 to 1 mm.
• the negative pressure conducting layer has a thickness a of l ⁇ 3 cm and a pore diameter of l ⁇ 1.5 mm.
• the negative pressure conducting layer has a thickness a of 3 to 6 cm and a pore diameter of 1 to 2.0 mm.
• the negative pressure conducting layer has a thickness a of 6 to 9 cm and a pore diameter of 1 to 2.5 mm.
• the drainage protective layer has a thickness b of 0.3 to 0.5 cm and a pore diameter of 0.2 to 0.5 mm.
• the drainage protective layer has a thickness b of 0.5 to 1.5 cm and a pore diameter of 0.5 to 1.0 mm.
• the drainage protective layer has a thickness b of 1.5 to 3.5 cm and a pore diameter of 0.8 to 1.0 mm.
• the negative pressure conducting layer is made of hydrophobic PU foam, EVA foam or PU foam of composite chitosan.
• the drainage protective layer is made of PVA foam, PVA foam of composite chitosan or PVA foam of composite antibacterial and bacteriostatic agent.
• the multi-layer foam dressing When the multi-layer foam dressing is used on the product of the negative pressure drainage tube installation, there are two longitudinal fractures, two longitudinal fractures are located at the position where the negative pressure drainage tube is to be installed, and one end opening is installed by the negative pressure drainage tube.
• the length of the longitudinal fracture can be as long as it passes through the position where the negative pressure drainage tube hole is installed.
• An outer surface layer is disposed on an upper portion of the negative pressure conducting layer, that is, a side away from the wound surface, and an outer surface layer is fixedly coupled to an upper portion of the negative pressure conducting layer.
• the outer surface layer is a porous foam outer surface layer, and the porous foam outer surface layer is a hydrophilic porous foam material layer.
• the porous foam outer surface layer has a thickness c of 0.1 to 0.5 cm.
• the outer surface layer is a layer of outer surface of the sealant film.
• the outer surface layer of the sealant film has a thickness of 0.1 ⁇ 0..5mm.
• One of the methods for making the multilayered foam dressing for vacuum sealing drainage of the present invention comprises the following steps:
• the cutting and cutting are performed to obtain a negative pressure conducting layer and a drainage protective layer;
• the negative pressure conductive layer foam material and the drainage protective layer foam material produced in the first step are fixedly connected by means of adhesive bonding, and the contact points on the two layers of porous foam material layer are provided with dispensing points. Adjacent two layers of porous foam material are laminated and bonded by a dry and hydrophilic composite glue at a dispensing point to form a composite layered structure;
• the second method for fabricating the multi-layered foam dressing for negative pressure closed drainage of the present invention comprises the following steps:
• the cutting and cutting are performed to obtain a negative pressure conducting layer and a drainage protective layer;
• the negative pressure conductive layer and the drainage protective layer are fixedly connected and stacked by means of a contact surface to form a multi-layered foam material;
• the multi-layered foam material prepared in the second step is perforated on the needle punching device, the pore diameter is l ⁇ 4 mm, and the needle body is penetrated through the adhesive layer to connect the two foam materials.
• Multi-layer foam dressing is
• the aperture of the perforation is 2 to 3 mm.
• the third method for fabricating the multi-layered foam dressing for negative pressure closed drainage of the present invention comprises the following steps:
• the negative pressure conductive layer and the drainage protective layer are prepared by cutting and cutting according to the design size
• the drainage protective layer cut in the first step is placed in the mold box, and an appropriate amount of the hydrophilic foam foaming raw material liquid is injected into the surface, and allowed to stand for 10-30 seconds, and the first surface is to be flattened.
• the negative pressure conductive layer cut in the step covers the surface of the raw material liquid, and the pressure is evenly applied by the tool to the negative pressure conductive layer, so that the negative pressure conductive layer and the original liquid surface are uniformly and uniformly contacted;
• the mold box for injecting the raw material liquid in the second step is heated, and the foaming raw material liquid is reacted and solidified, and the negative pressure conductive layer and the drainage protective layer are compositely joined together, and then the new foaming is performed in the middle.
• the foam bonding layer is cut and cut to obtain a double-layered foam dressing.
• the third method for manufacturing the multi-layered foam dressing for negative pressure closed drainage the third step of the foaming reaction process is first heated to 30 ⁇ 50 ° C for 0.5 to 1 hour to make it pre-mixed; Heat to 50 ⁇ 90 ° C for 2 to 8 hours.
• the preheating temperature is 35 to 45 ° C and the heating time is 0.5 hour.
• the temperature rise is 55 to 75 ° C and the heating time is 4 to 8 hours.
• the hydrophilic foam foaming raw material liquid in the third step further comprises an antibacterial agent, a bacteriostatic agent and a reinforcing agent in a total mass of the raw material liquid of 0.5% to 5%.
• the invention relates to a method for manufacturing a multi-layer foam dressing for negative pressure closed drainage and a porous foam outer surface layer, comprising the following steps:
• a method of adding a porous foam outer surface layer to the upper portion of the multi-layer foam dressing is: placing the negative pressure conductive layer of the double-layer foam dressing face down in the square mold box, and repeating the third method to obtain a three-layer foam dressing.
• the second method for manufacturing a multi-layer foam dressing for negative pressure closed drainage and a porous foam outer surface layer comprises the following steps:
• the upper layer of the prepared multi-layered foam dressing was glued, and the outer surface layer of the sealant film was adhered to the upper surface to obtain a three-layer foam dressing.
• the longitudinal fracture is located at the position where the negative pressure drainage pipe is installed, and the end of the installation of the negative pressure drainage pipe on the multi-layer foam dressing is inserted through the hole of the negative pressure drainage pipe. To the middle of the multi-layer foam dressing.
• a drainage protective layer is arranged on the lower layer of the foam dressing.
• the foam material is a hydrophilic foam material, which can effectively block the granulation tissue, avoid adhesion between the granulation tissue and the dressing, cause pulling bleeding, and effectively ensure the treatment. safety;
• Multi-layer structure negative pressure conduction layer is set in the middle, which is used for conducting negative pressure, which effectively improves the negative pressure conduction efficiency. While ensuring safety, it can effectively improve the negative pressure conduction performance of the dressing and avoid negative pressure conduction. Dead angle, guarantee the therapeutic effect;
• the hydrophilic foam material is used as a drainage protective layer to form a moist environment on the surface of the wound surface, which is beneficial to promote the growth of the wound granulation tissue and promote wound healing, and the hydrophilic environment can effectively reduce the suffering of the patient;
• the present invention is the first to propose a multi-layered foam dressing, which overcomes the clinical treatment of the clinical advantages of the clinically simple, single use of hydrophilic negative pressure materials or hydrophobic negative pressure materials. Troubled and distressed, using simple structural design and production methods, using a multi-layer structure, combining the advantages of the above materials, overcoming its shortcomings;
• the bottom drainage protective layer has higher hardness and elasticity due to its hydrophilic property, while the negative pressure conductive layer can ensure high negative pressure without loss during conduction, at high negative pressure Under the action, the bottom drainage protection layer can effectively divide the large necrotic tissue into small pieces, and the negative pressure conduction layer can effectively extract the necrotic tissue divided into small pieces, effectively avoiding the blockage of the negative pressure conduction layer material, and at the same time being more effective. Clean the wound, avoid the production of toxins, avoid the absorption of toxins, and reduce the incidence of infection;
• the dressing use time can be effectively extended.
• the above structure can effectively extend the dressing period and further alleviate the patient's pain. Reduce the cost of comprehensive treatment;
• the hydrophilic foam material is used as the drainage protective layer. Because the hydrophilic foam has high tensile strength and no chipping, it can effectively prevent the debris from entering the wound surface, which makes the wound healing difficult, and further improves the treatment safety of the foam dressing. Sex. DRAWINGS
• FIG. 1 is a schematic view of a first embodiment of a basic structure of the present invention
• Figure 2 is a schematic view showing the structure of the outer surface layer with a porous foam according to the embodiment 2 of the present invention
• FIG. 3 is a schematic structural view of an embodiment 3 of the present invention with an outer surface layer of a sealant film;
• Figure 4 is a perspective view of the three-dimensional structure of Figure 1;
• Figure 5 is a schematic plan view showing the structure of Figures 1, 2, 3 and the drainage tube;
• Figure 6 is a schematic view showing the structure of a needle punching device used for processing the product of the present invention.
• Figure 7 is a plan view of Figure 6;
• 1_negative pressure conducting layer 2_ draining protective layer, 3a—porous foam outer surface layer, 3b_sealing film outer surface layer, 4_needle punching device, 5_needle body, 6—in multiple layers Two longitudinal slits cut on the foam dressing.
• a multi-layered foam dressing for vacuum sealing drainage of the present invention comprises a negative pressure conducting layer 1 disposed at a lower portion of the negative pressure conducting layer 1 for contact with a wound or a wound cavity.
• the drainage protective layer 2, the negative pressure conductive layer 1 and the drainage protective layer 2 are both porous foam layers; the negative pressure conductive layer 1 is a hydrophobic porous foam material layer, and the drainage protective layer 2 is hydrophilic porous
• the foam layer is fixedly connected between the two layers of material and the pores are in contact with each other.
• the multi-layer foam dressing When the multi-layer foam dressing is applied to the product of the negative pressure drainage tube installation, there are two longitudinal fractures 6 which are located at a position where the negative pressure drainage tube is to be installed, and are installed by the negative pressure drainage tube. One end is open, and the length of the longitudinal slit 6 is only required to pass through the position where the negative pressure drainage tube hole is installed. Generally, the length of the longitudinal slit 6 is 1/10 to 1/2 of the length of the multilayered foam dressing.
• the effect of the two longitudinal fractures 6 is that the film can be exposed to the wound that has been seriously infected.
• the flow tube and the irrigation tube are turned over to the drainage protective layer 2 through the slit of the cut, and the negative pressure conductive layer 1 is directly contacted for treatment.
• the negative pressure conductive layer 1 has a thickness a of 0.5 to 10 cm and a pore diameter of 1 to 2.5 mm
• the drainage protective layer 2 has a thickness b of 0.1 to 3.5 cm and a pore diameter of 0.2 to 1 mm.
• the negative pressure conductive layer 1 has a thickness a of 1 to 3 cm and a pore diameter of 1 to 1.5 mm; and the drainage protective layer 2 has a thickness b of 0.5 to 1.5 cm and a pore diameter of 0.5 to 1.0 mm, which is suitable for forming a manifold, Sufficient drainage and negative pressure conduction of the sinus disease.
• the negative pressure conductive layer 1 has a thickness a of 3 to 6 cm and a pore diameter of 1 to 2.0 mm; the drainage protective layer 2 has a thickness b of 0.3 to 0.5 cm, and the pore diameter is 0.2 to 0.5 mm, which is suitable for various chronic and acute Traumatic, subacute and split wounds, burns, ulcers (such as diabetic ulcers and pressure ulcers), adequate drainage and negative pressure conduction of wounds such as flaps and skin grafts.
• the negative pressure conductive layer 1 has a thickness a of 6 to 9 cm and a pore diameter of 1 to 2.5 mm.
• the thickness of the drainage protection layer 2 is 1.5 to 3.5 cm, and the pore diameter is 0.8 to 1.0 mm, which is suitable for various openness. Adequate drainage and negative pressure conduction of abdominal cavity injury.
• the drainage protection layer 2 adopts the pore arrangement, which can facilitate the conduction of negative pressure on the one hand, and can effectively prevent the growth of granulation tissue into the foam pores on the other hand, and improve the overall safety and therapeutic effect of the foam dressing.
• the use of a thin drainage protection layer 2 can effectively reduce the negative impact of the hydrophilic foam layer on the negative pressure conduction, and a certain thickness can effectively block the wound granulation tissue.
• the use of a thicker negative pressure conducting layer 1 can effectively improve the overall negative pressure conduction properties of the foam dressing.
• the drainage protective layer 2 is preferably a hydrophilic porous foam layer.
• the drainage protective layer 2 can be made of PVA foam, PVA foam of composite chitosan or PVA foam of a composite antibacterial or bacteriostatic agent.
• the negative pressure conductive layer 1 is preferably a hydrophobic porous foam material layer. It can be made of hydrophobic PU foam, EVA foam or PU foam of composite chitosan. PU foams using composite chitosan are more suitable for the reverse use.
• the hydrophobic porous foam material has a larger pore size and a higher permeability, due to its hydrophobic nature, within the foam Generally, it does not contain water, so the negative pressure conduction performance is excellent, and the overall negative pressure conduction performance of the foam dressing can be effectively improved.
• the medical profession has caused many problems and distress in the clinical treatment of the advantages and disadvantages of clinically simple, single use of hydrophilic negative pressure materials or hydrophobic negative pressure materials.
• An outer surface layer 3 is disposed on an upper portion of the negative pressure conducting layer 1, that is, a side away from the wound surface, and an outer surface layer 3 is fixedly coupled to the upper portion of the negative pressure conducting layer 1 for preventing material from losing water; and, when used for endovascular treatment The outer surface layer 3 can effectively prevent the negative pressure conductive layer 1 from coming into direct contact with the wound tissue.
• Figure 2 is a schematic view showing the structure of the outer surface layer with a porous foam according to the embodiment 2 of the present invention
• the outer surface layer 3 is a porous foam outer surface layer 3a, and the porous foam outer surface layer 3a is a hydrophilic porous foam material layer.
• the porous foam outer surface layer 3a has a thickness c of 0.1 to 0.5 cm.
• Figure 3 is a schematic view showing the structure of the outer surface layer of the sealant film according to the embodiment 3 of the present invention:
• the outer surface layer 3 is a layer of a sealant outer surface layer 3b.
• the outer surface layer 3b of the sealant film has a thickness of 0.1 to 0.5 mm.
• One of the methods for making the multilayered foam dressing for vacuum sealing drainage of the present invention comprises the following steps:
• the negative pressure conductive layer 1 foam material and the drainage protective layer 2 foam material produced in the first step are fixedly connected by means of adhesive bonding, and the two porous foam material layer has a point on the contact surface. Glue point, the two layers of porous foam material are laminated and bonded by dry and hydrophilic composite glue at the dispensing point to form a composite layer structure.
• the second method for manufacturing a multi-layer foam dressing for negative pressure closed drainage and a porous foam outer surface layer comprises the following steps:
• the negative pressure conductive layer 1 and the drainage protective layer 2 are fixedly connected and stacked by means of a contact surface to form a multi-layered foam material;
• the multi-layered foam material prepared in the second step is perforated on the needle punching device, the pore diameter is l ⁇ 4 mm, and the needle body is penetrated through the adhesive layer to connect the two foam materials.
• Multi-layer foam dressing are schematic views showing the structure of a needle punching device for processing the product of the present invention:
• the aperture of the perforation is 2 to 3 mm.
• the third method for fabricating the multi-layered foam dressing for negative pressure closed drainage of the present invention comprises the following steps:
• the first step cutting and cutting according to the design size to obtain a negative pressure conductive layer 1 and a drainage protection layer 2;
• the drainage protective layer 2 which is cut in the first step is placed in a mold box, and an appropriate amount of the hydrophilic foam foaming raw material liquid is injected into the surface thereof, and left to stand for 10 to 30 seconds, and the surface is to be leveled.
• the negative pressure conductive layer 1 which is cut in one step covers the surface of the raw material liquid, and applies a pressure to the negative pressure conduction layer 1 by using a tool to uniformly and uniformly contact the negative pressure conductive layer 1 with the raw liquid surface;
• the mold box for injecting the raw material liquid in the second step is heated, and the foaming raw material liquid is reacted and solidified, and the negative pressure conductive layer 1 and the drainage protective layer 2 are compositely connected together, and then the new pair is newly formed.
• the foamed foam bonding layer is cut and cut to obtain a double-layered foam dressing.
• the foaming reaction is first heated to 30 to 50 ° C for 0.5 to 1 hour to pre-comply; and then heated to 50 to 90 ° C and heated for 2 to 8 hours. Heating to 30 ⁇ 50 °C is for better fusion, pre-expansion, and heating to 50 ⁇ 90 °C for heating 2 ⁇ 8 for better curing.
• the preheating temperature was 35 to 45 ° C, and the heating time was 0.5 hour.
• the heating temperature is 55 to 75 ° C, and the heating time is 4 to 8 hours.
• the hydrophilic foam foaming raw material liquid is mainly used for bonding, and its composition and proportion are similar to those of the drainage protective layer used in the product.
• the hydrophilic foam foaming raw material liquid in the third step further comprises an additive of 0.5% to 5% of the total mass of the raw material liquid, including but not limited to an antibacterial agent, a bacteriostatic agent, an enhancer and the like.
• the porous foam outer surface layer 3a is added to the upper portion of the multi-layered foam dressing by placing the negative pressure conductive layer 1 of the double-layer foam dressing in the square mold box downward, repeating the third method and the third method. In step, a three-layer foam dressing is obtained.
• the second method for producing the porous foam outer surface layer 3a on the upper portion of the multi-layered foam dressing is to apply the upper layer of the multi-layered foam dressing to the outer surface layer 3b of the sealant film to the upper surface to obtain a three-layer foam dressing.
• the longitudinal fracture is located at the position where the negative pressure drainage pipe is installed, and the end of the installation of the negative pressure drainage pipe on the multi-layer foam dressing is inserted through the hole of the negative pressure drainage pipe. To the middle of the multi-layer foam dressing.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of lcm, and the drainage protective layer 2 has a thickness of 0.5 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• the dressing has a three-layer structure with the negative pressure conducting layer 1 centered.
• the negative pressure conductive layer 1 is made of a hydrophobic foam material
• the drainage protective layer 2 is made of a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of lcm, and the drainage protective layer 2 has a thickness of 0.5 cm.
• the negative pressure conducting layer 1 has a pore diameter of 2.5 mm, and the bow I flow protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface layer 3a of the porous foam was added to have a diameter of 0.5 cm and a pore diameter of 0.5 mm.
• the dressing is a two-layer structure, which is formed by bonding a layer of negative pressure conductive layer 1 and a layer of drainage protective layer 2. Negative pressure conduction
• the layer 1 is made of a hydrophobic foam material
• the drainage protective layer 2 is made of a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of lcm, and the drainage protective layer 2 has a thickness of 0.5 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the bonding method is multi-point dispensing.
• the outer surface of the porous foam layer on the outer layer away from the side of the wound surface is fixedly connected with a layer of sealing film outer surface layer 3b.
• the dressing has a two-layer structure and is formed by bonding a layer of negative pressure conductive layer 1 and a layer of drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of lcm, and the drainage protective layer 2 has a thickness of 0.5 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the bonding method is surface bonding, and a through hole is formed in the adhesive layer, and the hole diameter is 2 mm.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 3 cm, and the drainage protective layer 2 has a thickness of 1 cm.
• the negative pressure conductive layer 1 has a pore diameter of 1.5 mm, and the drainage protective layer 2 has a pore diameter of 1 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 6 cm, and the drain protective layer 2 has a thickness of 0.75 cm.
• the negative pressure conducting layer 1 has a pore diameter of lmm, and the bow I flow protective layer 2 has a pore diameter of lmm.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 8 cm, and the drain protective layer 2 has a thickness of 1 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 10 cm, and the drain protective layer 2 has a thickness of 3.5 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• the dressing is a two-layer structure composed of a layer of a negative pressure conducting layer 1 and a layer of a drainage protective layer 2.
• the negative pressure conductive layer 1 is a hydrophobic foam material
• the drainage protective layer 2 is a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 6 cm, and the drain protective layer 2 has a thickness of 2.5 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm, and the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• the dressing is a two-layer structure, which is composed of a layer of negative pressure conductive layer 1 and a layer of drainage protection layer 2.
• the negative pressure conductive layer 1 is made of a hydrophobic foam material
• the drainage protective layer 2 is made of a hydrophilic foam material.
• the negative pressure conductive layer 1 has a thickness of 6 cm
• the drainage protective layer 2 has a thickness of 2 cm.
• the negative pressure conductive layer 1 has a pore diameter of 2.5 mm
• the drainage protective layer 2 has a pore diameter of 0.5 mm.
• the outer surface of the porous foam layer of the outer layer away from the wound surface is fixedly attached with a layer of sealing film outer surface layer 3b.
• Heating temperature and time are directly related to the mechanical strength and hardness of the product. The higher the temperature, the longer the heating time, the greater the mechanical strength and hardness; the lower the temperature, the shorter the heating time, the lower the mechanical strength and hardness of the product.
• the double-layer composite PVA was compared with the existing PVA dressings and PU dressings.
• the specific results are as follows:
• the first-stage treatment outcome time refers to the repair time of the wound bed after the treatment of the wound surface and the wound cavity by the negative pressure closed drainage technique can be used for the second-stage direct suture or skin graft or tissue flap transfer.
• Epithelialization rate The epithelialization process, including the three stages of migration, proliferation and differentiation of keratinocytes, is an important marker of tissue repair process; epithelialization rate is a significant indicator of the process of epithelialization.
• the amount of blood perfusion in the wound and wound cavity refers to the amount of blood per ml of wound or the wall of the wound cavity per ml of blood per minute.
• the wound volume of the wound and the wound cavity is larger. The more active the capillary is produced per unit area, the faster the growth rate of granulation tissue.
• PU m 00g-l.min-l
• the filling rate of granulation tissue refers to the proportion of filling of granulation tissue in wound and wound cavity; the larger the filling rate of granulation tissue, the more the wound and wound cavity are filled with new granulation, the wound healing
• Bacterial count refers to the number of viable bacteria per unit volume; the larger the bacterial count, the greater the possibility of infection.
• *K Comprehensive expenses, including material costs during hospitalization, drug costs such as antibiotics, surgery fees, treatment fees, bed fees, nutrition fees, etc.
• the product of the present invention is superior to the existing products in many aspects such as therapeutic effect and comprehensive treatment cost.
• the core of the present invention is a multi-layer composite foam dressing with a drainage protective layer on the outside, which subtly solves the poor safety performance of the existing negative pressure closed drainage foam dressing hydrophobic dressing material, and the hydrophilic dressing negative pressure. Poor conduction performance.
• a double or multi-layer structure can be used as needed, which is extremely flexible. Therefore, any changes or modifications made without departing from the principles of the invention are intended to be included within the scope of the invention.

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