A clinical hallmark of nicotine withdrawal is cognitive impairment; therefore, these animal and human studies suggest that modulation of central acetylcholine levels via dietary supplementation may be a valid adjunctive treatment during smoking cessation.
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Aug 9, 2018 ˇ Choline ameliorates adult learning deficits and reverses epigenetic modification of chromatin remodeling factors related to adolescent nicotine exposure.
Choline supplementation reversed the epigenetic modifications seen in chromatin remodeling genes, Smarca2 and Bahccl induced by nicotine (Gitik et al., 2018).
Dec 26, 2012 ˇ I've noticed that my desire to smoke is less when I'm drinking choline supplemented canned drinks which converts to Acetylcholine. I'm going to ...
Feb 10, 2010 ˇ Additional sequencing and characterization of ChAT may reveal functional variants that contribute to nicotine dependence and smoking cessation.
Mar 31, 2020 ˇ Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence.
Here, we summarize current efforts to develop smoking cessation therapeutics and highlight opportunities for future efforts.
Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence. Riju Ray, Nandita ...
May 6, 2015 ˇ There were no serious adverse events associated with CDP-choline and no adverse events led to discontinuation by any of the participants.
Dec 2, 2015 ˇ Behaviorally, removing acetylcholine from the habenula caused the mice to become insensitive to the rewarding properties of nicotine, and they ...