A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces
a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (…

The neural pathways for touch-induced movement in Caenorhabditis elegans contain six
touch receptors, five pairs of interneurons, and 69 motor neurons. The synaptic relationships …

Several bioluminescent coelenterates use a secondary fluorescent protein, the green
fluorescent protein (GFP), in an energy transfer reaction to produce green light. The most studied …

Three dominant mutations of mec-4, a gene needed for mechanosensation, cause the touch-receptor
neurons of Caenorhabditis elegans to degenerate. With deg-1, another C. elegans …

A little over 50 years ago, Sydney Brenner had the foresight to develop the nematode (round
worm) Caenorhabditis elegans as a genetic model for understanding questions of …

… Martin Chalfie … & Chalfie, M. Gene interactions affecting mechanosensory transduction
in Caenorhabditis elegans. Nature 367, 467–469 (1994). … Martin Chalfie …

Since the discovery of the gene for green fluorescent protein (GFP), derived from jellyfish,
this protein that emits a green glow has initiated a revolution in molecular biosciences. With …

The mec. 3 gene is essential for proper differentiation of the set of six touch receptor neurons
in C. elegans. In mutants lacking mec. 3 activity, the touch receptors express none of their …

Cells in the nematode Caenorhabditis elegans arise from invariant cell lineages. Mutations
in two genes, one-86 and/h-4, alter multiple and mutually exclusive sets of these lineages. In …

Touch sensitivity in the nematode Caenorhabditis elegans is mediated by a set of six sensory
neurons, the microtubule cells, of well-characterized anatomy and connectivity. The normal …