WO2003082908A3 - Use of the p17 protein of hiv in isolated form for the preparation of a medicament for administration to hiv seropositive patients, as well as pharmaceutical compositions comprising said protein - Google Patents
Use of the p17 protein of hiv in isolated form for the preparation of a medicament for administration to hiv seropositive patients, as well as pharmaceutical compositions comprising said protein Download PDFInfo
- Publication number
- WO2003082908A3 WO2003082908A3 PCT/EP2003/003177 EP0303177W WO03082908A3 WO 2003082908 A3 WO2003082908 A3 WO 2003082908A3 EP 0303177 W EP0303177 W EP 0303177W WO 03082908 A3 WO03082908 A3 WO 03082908A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hiv
- protein
- medicament
- administration
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003219101A AU2003219101A1 (en) | 2002-03-29 | 2003-03-27 | Use of the p17 protein of hiv in isolated form for the preparation of a medicament for administration to hiv seropositive patients, as well as pharmaceutical compositions comprising said protein |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002TO000286A ITTO20020286A1 (en) | 2002-03-29 | 2002-03-29 | USE OF THE PROTEIN P17 ISOLATED FOR THE PREPARATION OF A MEDICATION SUITABLE TO INHIBIT THE IMMUNOSTIMULATING EFFECTS THAT THE PROTEIN PRODUCED D |
ITTO2002A000286 | 2002-03-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003082908A2 WO2003082908A2 (en) | 2003-10-09 |
WO2003082908A3 true WO2003082908A3 (en) | 2004-03-25 |
Family
ID=27638968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/003177 WO2003082908A2 (en) | 2002-03-29 | 2003-03-27 | Use of the p17 protein of hiv in isolated form for the preparation of a medicament for administration to hiv seropositive patients, as well as pharmaceutical compositions comprising said protein |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2003219101A1 (en) |
IT (1) | ITTO20020286A1 (en) |
WO (1) | WO2003082908A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITTO20080027A1 (en) | 2008-01-15 | 2009-07-16 | Medestea Res & Production S P A | SHAPED FORM OF HIV PROTEIN P17. |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0293792A2 (en) * | 1987-06-01 | 1988-12-07 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus GAG-encoded proteins |
EP0322394A2 (en) * | 1987-11-24 | 1989-06-28 | Smithkline Biologicals S.A. | Expression of HIV proteins in E. coli and S. cerevisiae |
WO1998037089A2 (en) * | 1997-02-24 | 1998-08-27 | Oxford Biomedica (Uk) Limited | Matrix derived anti-hiv peptides and transdominant proteins |
WO2003016337A1 (en) * | 2001-08-07 | 2003-02-27 | Medestea Internazionale S.R.L. | Isolated polypeptides based on the neutralizing epitope of the p17 protein of hiv useful as vaccines, and neutralizing anti-p17 antibodies which specifically recognize said neutralizing epitope |
-
2002
- 2002-03-29 IT IT2002TO000286A patent/ITTO20020286A1/en unknown
-
2003
- 2003-03-27 WO PCT/EP2003/003177 patent/WO2003082908A2/en not_active Application Discontinuation
- 2003-03-27 AU AU2003219101A patent/AU2003219101A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0293792A2 (en) * | 1987-06-01 | 1988-12-07 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus GAG-encoded proteins |
EP0322394A2 (en) * | 1987-11-24 | 1989-06-28 | Smithkline Biologicals S.A. | Expression of HIV proteins in E. coli and S. cerevisiae |
WO1998037089A2 (en) * | 1997-02-24 | 1998-08-27 | Oxford Biomedica (Uk) Limited | Matrix derived anti-hiv peptides and transdominant proteins |
WO2003016337A1 (en) * | 2001-08-07 | 2003-02-27 | Medestea Internazionale S.R.L. | Isolated polypeptides based on the neutralizing epitope of the p17 protein of hiv useful as vaccines, and neutralizing anti-p17 antibodies which specifically recognize said neutralizing epitope |
Non-Patent Citations (5)
Title |
---|
CARUSO ARNALDO ET AL: "HIV-1 matrix protein p17 increases the production of proinflammatory cytokines and counteracts IL-4 activity by binding to a cellular receptor", FASEB JOURNAL, vol. 16, no. 4, 20 March 2002 (2002-03-20), Annual Meeting of the Professional Research Scientists on Experimental Biology;New Orleans, Louisiana, USA; April 20-24, 2002, pages A294, XP009019455, ISSN: 0892-6638 * |
FERNANDES J C ET AL: "THE ROLE CYTOKINES IN OSTEOARTHRITIS PATHOPHYSIOLOGY", BIORHEOLOGY, ELSEVIER SCIENCE LTD., OXFORD, GB, vol. 39, no. 1/2, April 2001 (2001-04-01), pages 237 - 246, XP008009498, ISSN: 0006-355X * |
FRANCESCO DE M A ET AL: "HIV-1 matrix protein p17 increases the production of proinflammatory cytokines and counteracts IL-4 activity by binding to a cellular receptor", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 99, no. 15, 23 July 2002 (2002-07-23), pages 9972 - 9977, XP002234153, ISSN: 0027-8424 * |
KIM J J ET AL: "CYTOKINE MOLECULAR ADJUVANTS MODULATE IMMUNE RESPONSES INDUCED BY DNA VACCINE CONSTRUCTS FOR HIV-1 AND SIV", JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, MARY ANN LIEBERT, NEW YORK, NY, US, vol. 19, no. 1, January 1999 (1999-01-01), pages 77 - 84, XP000971666, ISSN: 1079-9907 * |
ORLIKOWSKY THORSTEN W ET AL: "Dexamethasone inhibits CD4 T cell deletion mediated by macrophages from human immunodeficiency virus-infected persons", JOURNAL OF INFECTIOUS DISEASES, vol. 184, no. 10, 15 November 2001 (2001-11-15), pages 1328 - 1330, XP002258403, ISSN: 0022-1899 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003219101A8 (en) | 2003-10-13 |
ITTO20020286A1 (en) | 2003-09-29 |
AU2003219101A1 (en) | 2003-10-13 |
WO2003082908A2 (en) | 2003-10-09 |
ITTO20020286A0 (en) | 2002-03-29 |
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