In the town of Fairview there's a street called Wisteria Lane; a peaceful cul-de-sac with manicured lawns and beautiful houses. It's a place where you know all your neighbors and your neighbors know all about you. It's the perfect suburban fantasy. But, behind every picket fence there are secrets. And, in every seemingly happy home, you'll find jealousy, lust, passion, and sometimes…murder. It's always hot on Wisteria Lane. These women have it all: friendship, fun, love, sex, excitement, danger, and the men…well, the men don't stand a chance.