When Meredith's mother, Ellis, is brought to the hospital Ellis' illness is no longer a secret. George is chosen to take care of famous Ellis Grey, who thinks he is her husband Thatcher. Alex and Izzie become friends, very much to the objection of the other doctors. Derek is still mad at his wife, who tries to use her charm to make him forgive her. Christina passes out during an operation revealing her pregnancy to Dr. Burke. Dr. Webber is back as the head of the hospital.
—SSS